Results 11 to 20 of about 5,991,558 (223)

Electroanalytical Overview: The Sensing of Mesalamine (5-Aminosalicylic Acid) [PDF]

ACS Measurement Science Au, 2023
Robert D. Crapnell, Prashanth S. Adarakatti, Craig E. Banks   +2 more
doaj   +2 more sources

5-Aminosalicylic Acid Ameliorates Colitis and Checks Dysbiotic Escherichia coli Expansion by Activating PPAR-γ Signaling in the Intestinal Epithelium

mBio, 2021
An expansion of Enterobacterales in the fecal microbiota is a microbial signature of dysbiosis that is linked to many noncommunicable diseases, including ulcerative colitis.
Stephanie A. Cevallos, Jee-Yon Lee, Eric M Velazquez, N. J. Foegeding, Catherine D. Shelton, Connor R. Tiffany, Beau H Parry, Annica R. Stull-Lane, Erin E. Olsan, Hannah P. Savage, Henry Nguyen, Star S Ghanaat, Austin J Byndloss, Ilechukwu Agu, R. Tsolis, M. Byndloss, A. Bäumler   +16 more
semanticscholar   +1 more source

The safety of paternal and maternal use of 5‐aminosalicylic acid during conception and pregnancy: a nationwide cohort study

Alimentary Pharmacology and Therapeutics, 2022
Data on the safety of paternal use of 5‐aminosalicylic acid (5‐ASA) prior to conception are lacking, and the safety of maternal use of 5‐ASA during pregnancy has not been examined in nationwide data.
B. Nørgård, S. Friedman, J. Kjeldsen, J. Nielsen   +3 more
semanticscholar   +1 more source

Enteric-coated gelatin nanoparticles mediated oral delivery of 5-aminosalicylic acid alleviates severity of DSS-induced ulcerative colitis.

Materials Science and Engineering C: Materials for Biological Applications, 2021
Ulcerative colitis (UC) is an inflammatory condition involving ulcers in colon and rectum. Conventional treatments for colitis confront serious limitations like off target systemic side effects, drug degradation and inactivation, restricted absorption ...
Anas Ahmad, Md Meraj Ansari, R. Mishra, Ajay Kumar, A. Vyawahare, R. Verma, Syed Shadab Raza, Rehan Khan   +7 more
semanticscholar   +1 more source

Cyanidin-3-glucoside suppresses cytokine-induced inflammatory response in human intestinal cells: comparison with 5-aminosalicylic acid. [PDF]

PLoS ONE, 2013
The potential use of polyphenols in the prevention and treatment of chronic inflammatory diseases has been extensively investigated although the mechanisms involved in cellular signaling need to be further elucidated.
Diana Serra, Joana Paixão, Carla Nunes, Teresa C P Dinis, Leonor M Almeida   +4 more
doaj   +1 more source

Spectrophotometric Determination of para aminosalicylic acid in Serum Blood and Urin By Oxidative Coupling With 4-Amino Antipyrine and Study The Inhibition of Aldose Reductase Enzyme

Tikrit Journal of Pure Science, 2023
This work includes a new spectrophotometric method for the determination para aminosalicylic acid in aqueous medium based on the oxidation by  NaIO4 and coupling with 4-Amino Antipyrine producing a red dye soluble in water  and of גmax of 516 nm.
Asma'a H. Shakir
doaj   +1 more source

Aminosalicylic Acid

Reactions Weekly, 2006
europepmc   +2 more sources

The Synergistic Effects of 5-Aminosalicylic Acid and Vorinostat in the Treatment of Ulcerative Colitis

Frontiers in Pharmacology, 2021
Background: The drug 5-aminosalicylic acid (5-ASA) is the first-line therapy for the treatment of patients with mild-to-moderate ulcerative colitis (UC). However, in some cases, 5-ASA cannot achieve the desired therapeutic effects.
Long He, Shuting Wen, Zhuotai Zhong, Senhui Weng, Qilong Jiang, Hong Mi, Fengbin Liu   +6 more
semanticscholar   +1 more source

Repurposing a Drug Targeting Inflammatory Bowel Disease for Lowering Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The gut and gut microbiota, which were previously neglected in blood pressure regulation, are becoming increasingly recognized as factors contributing to hypertension. Diseases affecting the gut such as inflammatory bowel disease (IBD) present
Xue Mei, Blair Mell, Ishan Manandhar, Sachin Aryal, Ramakumar Tummala, Jun Kyoung, Tao Yang, Bina Joe   +7 more
doaj   +1 more source

Synthesis of a novel PEGylated colon-specific azo-based 4- aminosalicylic acid prodrug [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): 4-aminosalicylic acid (4-ASA) is an isomer of mesalazine that has recently been shown to be effective against inflammatory bowel disease (IBD), and more specifically, ulcerative colitis. However, the majority of orally administered 4-ASA is
Fatemeh Sadeghi, Atie Eidizade, Farinaz Saremnejad, Farzin Hadizadeh, Elham Khodaverdi, Abbas Akhgari   +5 more
doaj   +1 more source