Results 21 to 30 of about 15,403 (210)

4‑Aminosalicylic Acid Adducts

open access: yes, 2016
4-Aminosalicylic acid (p-aminosalicylic acid, PAS), an antituberculosis drug, is a model active pharmaceutical ingredient to study salt and cocrystal formation in a multiple hydrogen-bonding functionality molecule with carboxylic acid, amine, and phenol ...
Geetha Bolla (1744141)   +3 more
core   +7 more sources

Perimyocarditis in a Patient with Ulcerative Colitis Treated with 5-Aminosalicylic Acid [PDF]

open access: yesThe Korean Journal of Gastroenterology
5-Aminosalicylic acid (5-ASA) is recommended for managing ulcerative colitis. Common adverse effects associated with 5-ASA include gastrointestinal disorders, headaches, and skin rashes.
Hye Young Lee, Dong Hoon Baek
doaj   +2 more sources

5-Aminosalicylic Acid Distribution into the Intestinal Membrane Along the Gastrointestinal Tract After Oral Administration in Rats [PDF]

open access: yesPharmaceutics
Background: 5-Aminosalicylic acid (5-ASA), the first-line therapy for ulcerative colitis, is a poorly soluble zwitterionic drug. Unformulated 5-ASA is thought to be extensively absorbed in the small intestine.
Yorinobu Maeda   +7 more
doaj   +2 more sources

Preclinical Pharmacokinetics and Acute Toxicity in Rats of 5-{[(2E)-3-Bromo-3-carboxyprop-2-enoyl]amino}-2-hydroxybenzoic Acid: A Novel 5-Aminosalicylic Acid Derivative with Potent Anti-Inflammatory Activity

open access: yesMolecules, 2021
Compound 5-{[(2E)-3-bromo-3-carboxyprop-2-enoyl]amino}-2-hydroxybenzoic acid (C1), a new 5-aminosalicylic acid (5-ASA) derivative, has proven to be an antioxidant in vitro and an anti-inflammatory agent in mice.
Mara Gutiérrez-Sánchez   +5 more
doaj   +1 more source

Reaction of 5-aminosalicylic acid with peroxyl radicals: Protection and recovery by ascorbic acid and amino acids [PDF]

open access: yes, 2005
Purpose. The aims of the study are to analyze the interaction between 5-aminosalicylic acid (5-ASA) and peroxyl radicals and to evaluate the effect of some endogenous compounds such as ascorbic acid and amino acids on the oxidation of 5-ASA induced by 2 ...
Rocco, Claudia   +19 more
core   +1 more source

Pancreatitis: common but forgotten causes

open access: yesМедицинский вестник Юга России, 2021
Objective: to study the causes of pancreatitis. Materials and methods: a clinical case of acute pancreatitis during the treatment of ulcerative colitis with 5-aminosalicylic acid-containing drugs.
E. R. Donсova   +2 more
doaj   +1 more source

Preparation and in-vitro characterization of 5-aminosalicylic acid loaded hydrogels for colon specific delivery

open access: yesJournal of Materials Research and Technology, 2022
The aim of the current investigation was to prepare and characterize the novel pH-sensitive hydrogels of pluronic F127 and sodium polystyrene sulfonate for the controlled delivery of 5-aminosalicylic acid to colon.
Muhammad Suhail   +4 more
doaj   +1 more source

Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review

open access: yesAvicenna Journal of Medicine, 2012
Inflammatory bowel disease and its various treatments may affect the kidney in several ways. Recently, case reports have been published documenting the development of nephrotic syndrome after the treatment for inflammatory bowel disease with 5 ...
Belal M Firwana   +6 more
doaj   +1 more source

Crystal structure of methyl 2-hydroxy-5-[(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)amino]benzoate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
The title compound, C11H10N2O4S, crystallized with two independent molecules (A and B) in the asymmetric unit. They differ primarily in the rotational orientation of the five-membered heterocyclic ring.
Shaaban K. Mohamed   +4 more
doaj   +1 more source

Use of new, once-daily 5-aminosalicylic acid preparations in the treatment of ulcerative colitis. Is there anything new under the sun?

open access: yes, 2009
5-aminosalicylate (5-ASA) agents remain the mainstay treatment in ulcerative colitis (UC). A number of oral 5-ASA agents are commercially available, including azobond pro-drugs, as well as delayed- and controlled-release forms of mesalazine.
Lakatos, Péter László
core   +1 more source

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