Results 21 to 30 of about 5,991,558 (223)

Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach. [PDF]

PLoS ONE, 2014
Many advances have been recently made focused on the valuable help of dietary polyphenols in chronic inflammatory diseases. On the other hand, current treatment options for intestinal bowel disease patients are unsatisfying and, for this reason, it is ...
Diana Serra, Ana T Rufino, Alexandrina F Mendes, Leonor M Almeida, Teresa C P Dinis   +4 more
doaj   +1 more source

Amino Acid Derivatives of Aminosalicylic Acids† [PDF]

Journal of the American Pharmaceutical Association (Scientific ed.), 1953
Abstract A series of amide derivatives of 3‐, 4‐, and 5‐aminosalicylic acids with α‐amino acids has been prepared by a method which involves amide formation between the carboxyl group of the aminosalicylic acid and the amino group of the amino acid. The stability as well as the ease of formation of the compounds was increased by utilization of the O ...
W O, FOYE, R L, HULL
openaire   +2 more sources

Mesalazine induced focal segmental glomerulosclerosis in a patient with ulcerative colitis

Saudi Journal of Kidney Diseases and Transplantation, 2020
Focal segmental glomerulosclerosis (FSGS) and other glomerulonephritis due to the use of 5-aminosalicylic acid derivatives have been reported in the literature. A 38-year-old male who had been using mesalazine for four years because of ulcerative colitis
Fatih Yilmaz, Bora Uslu, Bahar Akkaya, Ramazan Cetinkaya   +3 more
doaj   +1 more source

Synthesis, characterization and radical scavenging activity of aromatic amine conjugates of 5-aminosalicylic acid

Bulletin of the Chemical Society of Ethiopia, 2014
5-Aminosalicylic acid is an anti-inflammatory drug used in the treatment of inflammatory bowel diseases including ulcerative colitis and Crohn’s disease.
K. Harveer, , S. Jasmeen
doaj   +1 more source

Preclinical Pharmacokinetics and Acute Toxicity in Rats of 5-{[(2E)-3-Bromo-3-carboxyprop-2-enoyl]amino}-2-hydroxybenzoic Acid: A Novel 5-Aminosalicylic Acid Derivative with Potent Anti-Inflammatory Activity

Molecules, 2021
Compound 5-{[(2E)-3-bromo-3-carboxyprop-2-enoyl]amino}-2-hydroxybenzoic acid (C1), a new 5-aminosalicylic acid (5-ASA) derivative, has proven to be an antioxidant in vitro and an anti-inflammatory agent in mice.
Mara Gutiérrez-Sánchez, Aurelio Romero-Castro, José Correa-Basurto, Martha Cecilia Rosales-Hernández, Itzia Irene Padilla-Martínez, Jessica Elena Mendieta-Wejebe   +5 more
doaj   +1 more source

Sodium para-aminosalicylic acid inhibits manganese-induced NLRP3 inflammasome-dependent pyroptosis by inhibiting NF-κB pathway activation and oxidative stress

Journal of Neuroinflammation, 2020
The activation of NOD-like receptor protein 3 (NLRP3) inflammasome-dependent pyroptosis has been shown to play a vital role in the pathology of manganese (Mn)-induced neurotoxicity.
Dongjie Peng, Junyan Li, Yue Deng, Xiaojuan Zhu, Lin Zhao, Yu-Wen Zhang, Zhao-cong Li, Shi-yan Ou, Shaojun Li, Yue-ming Jiang   +9 more
semanticscholar   +1 more source

5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis

Intestinal Research, 2020
Background/Aims 5-Aminosalicylic acid (ASA) causes intolerance reactions in some patients. This study was performed to examine the prognosis of patients with ulcerative colitis (UC) and 5-ASA intolerance, and to evaluate the potential interaction between
S. Mizuno, K. Ono, Y. Mikami, M. Naganuma, T. Fukuda, K. Minami, T. Masaoka, S. Terada, Takeshi Yoshida, Keiichiro Saigusa, N. Hirahara, H. Miyata, W. Suda, M. Hattori, T. Kanai   +14 more
semanticscholar   +1 more source

Application of 5-Aminosalicylic Acid Preparations in the Treatment of Inflammatory Bowel Diseases

Gastroenterologìa, 2016
The article is devoted to the comparative characterization of different derivatives of 5-aminosalicylic acid. Researches of the past decades have changed the presentation of the potential use of aminosalicylates in the therapy of various inflammatory ...
Yu.M. Stepanov, M.V. Stoykevich, O.V. Sorochan   +2 more
doaj   +1 more source

Pancreatitis: common but forgotten causes

Медицинский вестник Юга России, 2021
Objective: to study the causes of pancreatitis. Materials and methods: a clinical case of acute pancreatitis during the treatment of ulcerative colitis with 5-aminosalicylic acid-containing drugs.
E. R. Donсova, O. V. Remizov, N. V. Novoselya   +2 more
doaj   +1 more source

Preparation and in-vitro characterization of 5-aminosalicylic acid loaded hydrogels for colon specific delivery

Journal of Materials Research and Technology, 2022
The aim of the current investigation was to prepare and characterize the novel pH-sensitive hydrogels of pluronic F127 and sodium polystyrene sulfonate for the controlled delivery of 5-aminosalicylic acid to colon.
Muhammad Suhail, Ming-Chia Hung, I-Hui Chiu, Quoc Lam Vu, Pao-Chu Wu   +4 more
doaj   +1 more source