Results 171 to 180 of about 72,335 (302)

P‐Wave Parameter Changes After Pulsed‐Field Ablation, Cryoballoon Ablation and Radiofrequency Ablation for Paroxysmal Atrial Fibrillation: An Observational Cohort Study

open access: yesJournal of Arrhythmia, Volume 41, Issue 6, December 2025.
Pulsed‐field ablation, radiofrequency, and cryoballoon ablation produced similar acute changes in P‐wave indices on surface ECG. Increased post‐procedural P‐wave duration was the only robust predictor of atrial fibrillation recurrence, highlighting its prognostic value across modalities despite the limited sensitivity of body surface ECG for modality ...
Ibrahim Antoun   +6 more
wiley   +1 more source

Reduced Kidney Function and Left Atrial Dilatation as Predictors of Incident Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy

open access: yesJournal of Arrhythmia, Volume 41, Issue 6, December 2025.
New‐onset atrial fibrillation (AF) occurred in 22% of patients with hypertrophic cardiomyopathy, corresponding to an incidence rate of 2.8 per 100 person‐years. Reduced kidney function and left atrial dilatation were independently associated with AF onset, indicating the need for closer monitoring and regular renal assessments in this population ...
Yuriko Tsumaya   +21 more
wiley   +1 more source

Efficacy of Sacubitril/Valsartan Among Heart Failure Individuals With Implanted Cardiac Defibrillators: A Systematic Review and Meta‐Analysis

open access: yesJournal of Arrhythmia, Volume 41, Issue 6, December 2025.
This meta‐analysis suggested that sacubitril/valsartan could significantly reduce the incidence of ICD shocks, NSVT duration andBiv pacing < 90% among patients with heart failure and ICD. Evidence for ventricular arrhythmia reduction, PVC/h, and improvement in LVEF remains unclear due to short follow‐up and a limited number of studies.
Hila Asham   +5 more
wiley   +1 more source

Toward a Quantitative Understanding of Aficamten Clinical Pharmacology: Population Pharmacokinetic Modeling

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 12, Page 1982-1992, December 2025.
ABSTRACT Aficamten is a next‐in‐class, cardiac myosin inhibitor in development as a potential chronic oral treatment for patients with hypertrophic cardiomyopathy (HCM). A population pharmacokinetic (PK) model was developed using data from nine clinical studies to characterize aficamten PK and identify covariates that may alter aficamten exposure ...
Donghong Xu   +6 more
wiley   +1 more source

The Story of Amiodarone [PDF]

open access: yesEuropean Heart Journal, 2019
Hamed, Tavolinejad   +4 more
openaire   +2 more sources

A Dose‐Aware Model for Revealing Dose‐Risk Relationship of Drug–Drug Interaction

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 12, Page 2086-2094, December 2025.
ABSTRACT Drug–drug interaction (DDI) is a common cause of adverse drug events (ADEs). Despite real‐world data‐based studies have developed knowledge on DDI, the precise relationships between doses of two‐drug combinations exposure and the risks of ADEs remain largely unknown.
Yi Shi   +8 more
wiley   +1 more source

Prospective randomized study comparing amiodarone vs. amiodarone plus losartan vs. amiodarone plus perindopril for the prevention of atrial fibrillation recurrence in patients with lone paroxysmal atrial fibrillation [PDF]

open access: bronze, 2006
Yuehui Yin   +12 more
openalex   +1 more source

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