Results 1 to 10 of about 56,967 (294)
Amitriptyline and Imipramine [PDF]
John M. Hoenig
openaire +4 more sources
The half‐life of amitriptyline. [PDF]
PJ Morrison, Howard Rogers, ID Bradbrook
openaire +5 more sources
Objective The aim of this paper is to critically re-appraise the published trials assessing amitriptyline for migraine prophylaxis. Methods We report our methods and results following the Preferred Reporting Items for Systematic Reviews (PRISMA), by ...
C. Lampl+14 more
semanticscholar +1 more source
Background Half the US population uses drugs with anticholinergic properties. Their potential harms may outweigh their benefits. Amitriptyline is among the most frequently prescribed anticholinergic medicinal products, is used for multiple indications ...
Maria-Sophie Brueckle+9 more
semanticscholar +1 more source
Comparison of Amitriptyline and US Food and Drug Administration–Approved Treatments for Fibromyalgia
This systematic review and network meta-analysis compares amitriptyline with Food and Drug Administration–approved treatments for fibromyalgia related to sleep, fatigue, and health-related quality of life outcomes.
H. M. Farag+5 more
semanticscholar +1 more source
The Acid Sphingomyelinase Inhibitor Amitriptyline Ameliorates TNF-α-Induced Endothelial Dysfunction
Inflammation associated endothelial cell (EC) dysfunction is key to atherosclerotic disease. Recent studies have demonstrated a protective role of amitriptyline in cardiomyocytes induced by hypoxia/reoxygenation.
Yang Ji+12 more
semanticscholar +1 more source
Osteoarthritis, a major cause of disability in developed countries does not have effective treatment. Activation of TLR4 and innate immune response factors contribute to osteoarthritis progressive cartilage degradation.
E. Franco-Trepat+9 more
semanticscholar +1 more source
The tricyclic antidepressant amitriptyline is frequently prescribed but its use is limited by its narrow therapeutic range and large variation in pharmacokinetics.
J. Matthaei+9 more
semanticscholar +1 more source
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a cytokine with the potential to induce cancer cell-specific apoptosis with minimal toxicity to normal cells. Therefore, the resistance of certain cancer cells to TRAIL is a major concern
K. Zinnah, Sang-Youel Park
semanticscholar +1 more source
Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump
Efflux pumps of the resistance nodulation-cell division (RND) superfamily are major contributors to multidrug resistance for most of the Gram-negative ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii ...
E. Grimsey+10 more
semanticscholar +1 more source