Results 1 to 10 of about 43,004 (300)

Evaluation of the testicular protection conferred by damiana (Turnera diffusa Willd.) against amitriptyline-induced testicular toxicity, DNA damage and apoptosis in rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
Psychiatric drugs, such as antidepressants, are used to treat depression based on their ability to modify chemical imbalances of the key neurotransmitters in the brain, including dopamine, serotonin, and norepinephrine.
Ehab Tousson, Ezar H. Hafez, Somia Zaki, Amani Gad, R. M. Elgharabawy   +4 more
semanticscholar   +1 more source

Amitriptyline interferes with autophagy-mediated clearance of protein aggregates via inhibiting autophagosome maturation in neuronal cells

Cell Death and Disease, 2020
Amitriptyline is a tricyclic antidepressant commonly prescribed for major depressive disorders, as well as depressive symptoms associated with various neurological disorders.
Y. Kwon, Yeojin Bang, Soung-Hee Moon, Aeri Kim, H. Choi   +4 more
semanticscholar   +1 more source

Pharmacological Evaluation of Antidepressant-Like Effect of Genistein and Its Combination with Amitriptyline: An Acute and Chronic Study

Advances in Pharmacological Sciences, 2015
The present study was designed to evaluate the acute and chronic antidepressant effect of genistein in combination with amitriptyline in mice. Animals were divided into six groups (n=6) for treatment with water, genistein, or amitriptyline, either alone ...
Gaurav Gupta, Tay Jia Jia, Lim Yee Woon, Dinesh Kumar Chellappan, Mayuren Candasamy, Kamal Dua   +5 more
doaj   +1 more source

Effect of herb-drug interactions of Bacopa monnieri Linn. (Brahmi) formulation on the pharmacokinetics of amitriptyline in rats

Brazilian Journal of Pharmaceutical Sciences, 2018
Interactions between herbs and drugs may increase or decrease the pharmacological or toxicological effects of either component. Experimental data on the pharmacokinetic interactions between herbal products and drugs are limited.
Fowad Khurshid, Jeyabalan Govindasamy, Habibullah Khalilullah, Mohammed Shivli Nomani, Mudassar Shahid, Md Ruhal Ain, Mohammad Sultan Alsultan   +6 more
doaj   +1 more source

Case Report: Auditory Hallucination Induced by Amitriptyline for the Treatment of Atypical Odontalgia

Frontiers in Psychiatry, 2022
Auditory hallucination is usually associated with psychiatric diseases and organic brain illness. It was rarely found as adverse events of antidepressants.
Motoko Watanabe, Tetsuo Nakabayashi, Gayatri Nayanar, Chihiro Takao, Chizuko Maeda, Trang Thi Huyen Tu, Trang Thi Huyen Tu, Haruhiko Motomura, Akira Toyofuku   +8 more
doaj   +1 more source

The adsorption of amitriptyline and nortriptyline on activated carbon, diosmectite and titanium dioxide

, 2020
The adsorption of the tricyclic antidepressants amitriptyline and nortryptyline was studied. Activated carbon, diosmectite and nano-sized titanium dioxide were selected as adsorbent materials.
R. Maršálek, Martin Švidrnoch
semanticscholar   +1 more source

Analgesic Effects of Topical Amitriptyline in Patients with Chemotherapy-Induced Peripheral Neuropathy: Mechanistic Insights from Studies in Mice.

Journal of Pain, 2020
Oral amitriptyline hydrochloride (amitriptyline) is ineffective against some forms of chronic pain and is often associated with dose-limiting adverse events.
Anne-Laure Genevois, Jérôme Ruel, Virginie Penalba, Séverine Hatton, Camille Petitfils, M. Ducrocq, P. Principe, G. Dietrich, C. Greco, P. Delmas   +9 more
semanticscholar   +1 more source

Pretreatment with intrathecal amitriptyline potentiates anti-hyperalgesic effects of post-injury intra-peritoneal amitriptyline following spinal nerve ligation

BMC Neurology, 2012
Background Amitriptyline, a tricyclic antidepressant and potent use-dependent blocker of sodium channels, has been shown to attenuate acute and chronic pain in several preclinical modes.
Cheng Kuang-I, Wang Hung-Chen, Chang Lin-Li, Wang Fu-Yen, Lai Chung-Sheng, Chou Chao-Wen, Tsai Hung-Pei, Kwan Aij-Lie   +7 more
doaj   +1 more source

Evaluation the effect of amitriptyline and/or ashwagandha on body weight in male rats

Al-SalamJournal for Medical Science, 2023
study aims to examine and compare the effects of amitriptyline and ashwagandha on body weight in male rats by measurement weight for 4 weeks after their exposure to these two compound.
Ghada A. Taqa, Ismail R. Idrees
doaj   +1 more source

Trial of Amitriptyline, Topiramate, and Placebo for Pediatric Migraine

New England Journal of Medicine, 2016
Background Which, medication, if any, to use to prevent the headache of pediatric migraine has not been established. Methods We conducted a randomized, double‐blind, placebo‐controlled trial of amitriptyline (1 mg per kilogram of body weight per day ...
S. Powers, C. Coffey, L. A. Chamberlin, Dixie Ecklund, Elizabeth A. Klingner, Jon W. Yankey, L. Korbee, L. Porter, A. Hershey   +8 more
semanticscholar   +1 more source