Results 11 to 20 of about 29,828 (259)

Repeated Administration of Amitriptyline Reduces Oxaliplatin-Induced Mechanical Allodynia in Rats

open access: yesJournal of Pharmacological Sciences, 2012
Oxaliplatin is a key drug in the treatment of colorectal cancer, but it causes acute and chronic neuropathies in patients. Amitriptyline has widely been used in patients with painful neuropathy.
Hikaru Sada   +5 more
doaj   +2 more sources

Amitriptyline induced cervical dystonia

open access: yesJournal of the Scientific Society, 2016
Tricyclic antidepressants (TCAs), such as amitriptyline, have many side effects. But extrapyramidal tract symptom is an uncommon side effect of these drugs. Here, we report a case of a 28-year-old male who is suffering from amitriptyline induced cervical
Shivanand B Hiremath, Mahesh Desai
doaj   +2 more sources

Correlation between Amitriptyline-Induced Cardiotoxic Effects and Cardiac S100b Protein in Isolated Rat Hearts

open access: yesBalkan Medical Journal, 2016
Background: Amitriptyline is an important cause of mortality due to its cardiovascular toxicity. Aims: To investigate the changes in levels of cardiac S100b protein on amitriptyline-induced cardiotoxicity and also to examine the correlation between ...
Nil Hocaoğlu   +5 more
doaj   +2 more sources

Mechanisms of the Cardiotoxic Action of Amitriptyline [PDF]

open access: yesОбщая реаниматология, 2011
Objective: to study the mechanisms of toxic action of amitriptyline on the myocardium. Material and methods. Investigations were conducted using the hearts from 30 outbred albino rats, which had been isolated and perfused according to the procedure ...
G. V. Chekmarev, V. T. Dolgikh
doaj   +2 more sources

Dermal delivery of amitriptyline for topical analgesia [PDF]

open access: yes, 2021
Amitriptyline, administered orally, is currently one of the treatment options for the management of neuropathic pain and migraine. Because of the physicochemical properties of the molecule, amitriptyline is also a promising candidate for delivery as a ...
Sil dos Santos, Bruno   +13 more
core   +1 more source

Dermal delivery of amitriptyline for topical analgesia [PDF]

open access: yes, 2022
Amitriptyline, administered orally, is currently one of the treatment options for the management of neuropathic pain and migraine. Because of the physicochemical properties of the molecule, amitriptyline is also a promising candidate for delivery as a ...
Lane, M   +6 more
core   +1 more source

Effects of Adding Dexmedetomidine to Amitriptyline on Sciatic Nerve Blockadge in Rats

open access: yesMedicine Science, 2013
Neurotoxic effects of amitriptyline which is a tricyclic antidepressant limit its use as a local anesthetic. In this study, comparing the effect of combination of different amitrptyline doses with dexmedetomidine on block initiation and termination time ...
Mahmut Durmus   +5 more
doaj   +1 more source

The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats

open access: yesClinics, 2010
OBJECTIVE: The present study was designed to further investigate the effect of amitriptyline, a classical tricyclic antidepressant, on carrageenan-induced paw edema in rats. METHODS: First, amitriptyline was administered intraperitoneally (i.p.) at doses
Valiollah Hajhashemi   +4 more
doaj   +1 more source

Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]

open access: yes, 2002
Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Marcuse, Alain   +4 more
core   +1 more source

Percutaneous electrical nerve field stimulation compared to standard medical therapy in adolescents with functional abdominal pain disorders

open access: yesFrontiers in Pain Research, 2023
IntroductionStandard medical therapy (SMT) in children with functional abdominal pain disorders (FAPD) includes cyproheptadine and amitriptyline. While percutaneous electrical nerve field stimulation (PENFS) has shown benefit, no study has compared ...
Neha R. Santucci   +11 more
doaj   +1 more source

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