Results 41 to 50 of about 4,707 (142)

Analysis of the effects of a tricyclic antidepressant on secondary sleep disturbance induced by chronic pain in a preclinical model.

open access: yesPLoS ONE, 2020
Chronic pain and sleep have a bidirectional relationship that promotes a vicious circle making chronic pain more difficult to treat. Therefore, pain and sleep should be treated simultaneously.
Hisakatsu Ito   +5 more
doaj   +1 more source

Pregabalin and amitriptyline as monotherapy or as low-dose combination in patients of neuropathic pain: A randomized, controlled trial to evaluate efficacy and safety in an Eastern India teaching hospital

open access: yesAnnals of Indian Academy of Neurology, 2019
Objectives: The main objective is to compare efficacy and safety of pregabalin and amitriptyline monotherapy with their low-dose combination in patients of neuropathic pain (NeuP).
Sourav Chakrabarty   +5 more
doaj   +1 more source

Dermal delivery of amitriptyline for topical analgesia [PDF]

open access: yes
Amitriptyline, administered orally, is currently one of the treatment options for the management of neuropathic pain and migraine. Because of the physicochemical properties of the molecule, amitriptyline is also a promising candidate for delivery as a ...
Sil dos Santos, Bruno   +6 more
core   +1 more source

Pharmacokinetics of Amitriptyline Demethylation;A Crossover Study with Single Doses of Amitriptyline and Nortriptyline [PDF]

open access: yes, 1990
A single dose crossover pharmacokinetic study of amitriptyline and nortriptyline was done to find out the extent of first-pass metabolism to nortriptyline after amitripyline administration, and the contribution of nortriptyline during amitriptyline ...
Jang, In-Jin   +6 more
core  

Amitriptyline Blood Levels and Relapse

open access: yes, 1977
Nine previously depressed patients who had responded either to amitriptyline, nortriptyline, or ECT, according to defined criteria, were followed for six months on either 150 mg. or 75 mg. amitriptyline daily, double blind.
F.W. Furlong, B.M. Kapur, E.M. Sellers
core   +1 more source

Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study

open access: yesArquivos de Neuro-Psiquiatria, 2014
To compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine. Method Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were ...
Michelle Dias Santos Santiago   +5 more
doaj   +1 more source

Efficacy of amitriptyline in the treatment of subjective tinnitus

open access: yes, 2001
We investigated the effect of amitriptyline, a tricyclic antidepressant, on patients with subjective tinnitus. The study group consisted of 37 adult patients admitted to the Ear, Nose, and Throat and Audiology Department of Hacettepe University.
Bayar, N.   +3 more
core   +2 more sources

Protocol of a systematic review : Efficacy of Amitriptyline for fibromyalgia

open access: yes, 2022
Domain being studied : Fibromyalgia - amitriptyline Search strategy : all article with key-word « amitriptyline » in PubMed, ClinicalTrial.gouv and The Cochrane Central Registration with restiction of randomised controlled trials Population : Adults over
BARO, Houdna LAIB, GUICHARDANT Valérie
core   +1 more source

Comparing the efficacy and safety of duloxetine and amitriptyline in the treatment of fibromyalgia: overview of systematic reviews

open access: yesAdvances in Rheumatology, 2020
Background Duloxetine and amitriptyline are antidepressants used in the treatment of fibromyalgia. In published systematic reviews, there is no agreement about which drug is more effective and safer.
Áurea Dias de Farias   +3 more
doaj   +1 more source

Cytotoxic effects of amitriptyline in human fibroblasts

open access: yes, 2007
8 páginas, 6 figuras.Amitriptyline is a tricyclic antidepressant widely used in the treatment of chronic pain. The objective of the present study was to investigate the potential cytotoxic effects of amitriptyline in human fibroblasts primary culture ...
Moreno-Fernández, Ana M.   +5 more
core   +1 more source

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