Results 31 to 40 of about 29,828 (259)
, 1995 1 The block of K+ currents by amitriptyline and the related tricyclic compounds cyproheptadine and dizocilpine was studied in dissociated rat sympathetic neurones by whole-cell voltage-clamp recording.
Mathie, A., Wooltorton, J.R.
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Toxics, 2022 Pharmaceuticals such as antidepressants are designed to be bioactive at low concentrations. According to their mode of action, they can also influence non-target organisms due to the phylogenetic conservation of molecular targets.
Hannah Schmieg +7 more
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Efficacy of amitriptyline in the treatment of subjective tinnitus
, 2001 We investigated the effect of amitriptyline, a tricyclic antidepressant, on patients with subjective tinnitus. The study group consisted of 37 adult patients admitted to the Ear, Nose, and Throat and Audiology Department of Hacettepe University.
Bayar, N. +7 more
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PharmaceuticalsBackground: A large number of patients suffer from neuropathic pain, and systemic therapy often remains ineffective while inducing severe side effects. Topical therapy with the TRPV1-agonist capsaicin is an established alternative, and the identification
Sebastian Pantke +7 more
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Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity. [PDF]
PLoS ONE, 2011 Approximately 35 million people worldwide suffer from Alzheimer's disease (AD). Existing therapeutics, while moderately effective, are currently unable to stem the widespread rise in AD prevalence.
Wayne Chadwick +11 more
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Cytotoxic effects of amitriptyline in human fibroblasts
, 2007 8 páginas, 6 figuras.Amitriptyline is a tricyclic antidepressant widely used in the treatment of chronic pain. The objective of the present study was to investigate the potential cytotoxic effects of amitriptyline in human fibroblasts primary culture ...
Moreno-Fernández, Ana M. +5 more
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Protocol of a systematic review : Efficacy of Amitriptyline for fibromyalgia
, 2022 Domain being studied : Fibromyalgia - amitriptyline Search strategy : all article with key-word « amitriptyline » in PubMed, ClinicalTrial.gouv and The Cochrane Central Registration with restiction of randomised controlled trials Population : Adults over
BARO, Houdna LAIB, GUICHARDANT Valérie
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British Journal of Clinical Pharmacology, EarlyView.Aims Careful consideration of drug–drug interactions (DDIs) is critical as people with HIV age. We analysed queries submitted to the University of Liverpool HIV Drug Interactions Database to assess changes in prescribing patterns over 5 years. Methods Queries submitted between January 2020 and December 2024 were extracted and categorized by year ...
Cecile Gras +6 more
wiley +1 more source
A Brief Review of the Pharmacology of Amitriptyline and Clinical Outcomes in Treating Fibromyalgia
Biomedicines, 2017 Fibromyalgia is a complex chronic condition characterized by pain, physical fatigue, sleep disorder and cognitive impairment. Evidence-based guidelines recommend antidepressants as treatments of fibromyalgia where tricyclics are often considered to have ...
Kim Lawson
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PLoS ONE, 2020 Chronic pain and sleep have a bidirectional relationship that promotes a vicious circle making chronic pain more difficult to treat. Therefore, pain and sleep should be treated simultaneously.
Hisakatsu Ito +5 more
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