Results 51 to 60 of about 4,707 (142)

Amitriptyline for migraine prophylaxis in adolescents

, 2011
headaches in children and adolescents. Amitriptyline efficacy as a prophylactic treatment for migraine in adults has been widely studied, but there is limited data on its use in children and adolescents.Objective To determine the efficacy of ...
Pranoto Trilaksono, Yazid Dimyati, Johannes H. Saing, Bistok Saing, Astri Nurhayati Zulkifli   +4 more
core   +1 more source

Effect of amitriptyline antidotes on repetitive extrasystole threshold [PDF]

, 1980
The effect of amitriptyline that leads to ventricular tachycardia was evaluated by the repetitive extrasystole threshold (RET) technique in 18 dogs.
Tobis, Jonathan M, Jonathan M Tobis, Aronow, Wilbert S, Wilbert S Aronow   +3 more
core   +1 more source

Amitriptyline inhibits bronchoconstriction independent of direct receptor binding and reduces number of caveolae

Scientific Reports
Bronchial asthma is a chronic inflammatory disease with rising prevalence worldwide. Apart from the immunological role of the tricyclic antidepressant amitriptyline in bronchial asthma, there is emerging evidence that inhaled amitriptyline directly ...
Virag Klein, Anna Michely, Paulina Hempel, Istvan Katona, Klaus Tenbrock, Christian Martin, Eva Verjans   +6 more
doaj   +1 more source

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT

Health Technology Assessment, 2022
Background: The mainstay of treatment for diabetic peripheral neuropathic pain is pharmacotherapy, but the current National Institute for Health and Care Excellence guideline is not based on robust evidence, as the treatments and their combinations have ...
Solomon Tesfaye, Gordon Sloan, Jennifer Petrie, David White, Mike Bradburn, Tracey Young, Satyan Rajbhandari, Sanjeev Sharma, Gerry Rayman, Ravikanth Gouni, Uazman Alam, Steven A Julious, Cindy Cooper, Amanda Loban, Katie Sutherland, Rachel Glover, Simon Waterhouse, Emily Turton, Michelle Horspool, Rajiv Gandhi, Deirdre Maguire, Edward Jude, Syed Haris Ahmed, Prashanth Vas, Christian Hariman, Claire McDougall, Marion Devers, Vasileios Tsatlidis, Martin Johnson, Didier Bouhassira, David L Bennett, Dinesh Selvarajah   +31 more
doaj   +1 more source

Topical amitriptyline in healthy volunteers [PDF]

, 2003
Background and Objectives: The antidepressant amitriptyline is used as an adjuvant in the treatment of a variety of chronic pain conditions. This drug interacts with many receptors and ion channels, such as Na ϩ channels. In a randomized, double-blinded,
B A, M.D Venkatesh Srinivasa, M.D Sanjeet Narang, Grace Kao, Ph.D Ging Kuo Wang, M.D Peter Gerner   +5 more
core  

Effects of BQ-788 on amitriptyline-induced cardiovascular toxicity.

, 2013
Objective: We investigated both the effects of the endothelin type B (ETB) receptor antagonist, BQ-788, on amitriptyline-induced cardiotoxicity and the role of ETB receptors on amitriptyline-induced cardiovascular depression.
Arıcı, MUALLA AYLİN, Tunçok, Yeşim, Kalkan, Şule, Büyükdeligöz, Müjgan   +3 more
core   +1 more source

Modulation of nociception by amitriptyline hydrochloride in the Speke’s hinge‐back tortoise (Kiniskys spekii)

Veterinary Medicine and Science, 2021
Background There are limited studies on the utilization of analgesics in testudines. Management of pain in reptiles is by use of analgesics generally used in other vertebrate species.
Christopher M. Makau, Philemon K. Towett, Klas S.P. Abelson, Titus I. Kanui   +3 more
doaj   +1 more source

Amitriptyline versus placebo for major depressive disorder.

, 2012
Amitriptyline is a tricyclic antidepressant that was synthesised in 1960 and introduced as early as 1961 in the USA, but is still regularly used.
Leucht, C;Huhn, M;Leucht, S
core   +1 more source

Further Studies in Adenosinergic and Monoaminergic Mechanisms of Analgesia by Amitriptyline

, 2012
In this thesis, rodent models of chronic pain were used to explore analgesic mechanisms that may potentially be engaged in spinal and peripheral compartments by systemically-administered amitriptyline, a tricyclic antidepressant.
Liu, Jean
core  

Changes in electrical activity of heart during ischemic–reperfusion injury modified by the administration of antidepressants

European Pharmaceutical Journal, 2016
The aim of our work was to investigate the effect of amitriptyline, citalopram and venlafaxine on the heart during ischemic- reperfusion (l-R) injury.
Vicen M., Gulač P., Stankovičová T.
doaj   +1 more source