Results 61 to 70 of about 29,828 (259)

Examination and characterisation of the effect of amitriptyline therapy for chronic neuropathic pain on neuropeptide and proteomic constituents of human cerebrospinal fluid

Brain, Behavior, & Immunity - Health, 2021
Introduction: Amitriptyline is prescribed to reduce the intensity of chronic neuropathic pain. There is a paucity of validated in vivo evidence in humans regarding amitriptyline’s mechanism of action.
Jonathan Royds, Hilary Cassidy, Melissa J. Conroy, Margaret R. Dunne, Joanne Lysaght, Connail McCrory   +5 more
doaj   +1 more source

Efficacy of Ultrasound‐Guided Intercostal Nerve Block With Liposomal Bupivacaine for Treating Postherpetic Neuralgia in Adult Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to investigate the efficacy of ultrasound‐guided intercostal nerve block (ICNB) with liposomal bupivacaine (LB) comparing ropivacaine‐dexamethasone (RD) for treating postherpetic neuralgia (PHN) in adult patients. A total of 108 patients were randomized 1:1 to receive ICNB with LB or ICNB with RD.
Jin Li, Xiang‐Yu Fang
wiley   +1 more source

Removal of amitriptyline from aqueous media using activated carbons

, 2012
This paper reports the removal of amitriptyline, a widely used tricyclic anti-depressant, from aqueous solutions by six activated carbons produced from cork, coffee endocarp and eucalyptus pulp. The results of this study showed that samples from cork and
Ledesma, Beatriz, Laginhas, Carlos, Valente Nabais, Joao, C. Laginhas, B. Ledesma, J.M. Valente Nabais   +5 more
core   +1 more source

Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes

The Laryngoscope, EarlyView.
A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar, Eric Allen, Yun‐Lun Liu, Alexandra D. D'Oto, Rishi Suresh, Adrianna Shembel, Ted Mau   +6 more
wiley   +1 more source

Amitriptyline inhibits bronchoconstriction independent of direct receptor binding and reduces number of caveolae

Scientific Reports
Bronchial asthma is a chronic inflammatory disease with rising prevalence worldwide. Apart from the immunological role of the tricyclic antidepressant amitriptyline in bronchial asthma, there is emerging evidence that inhaled amitriptyline directly ...
Virag Klein, Anna Michely, Paulina Hempel, Istvan Katona, Klaus Tenbrock, Christian Martin, Eva Verjans   +6 more
doaj   +1 more source

Supraglottic Botulinum Toxin Injection Improves Symptoms of Laryngeal Sensory Dysfunction

The Laryngoscope, EarlyView.
In this retrospective cohort of 80 patients with refractory laryngeal sensory symptoms, supraglottic botulinum toxin type A significantly improved Laryngeal Hypersensitivity Questionnaire, Reflux Symptom Index, and Cough Severity Index scores at a mean of 5.2 weeks, while Voice Handicap Index‐10 scores remained unchanged.
Daniel Novakovic, Katrina Sandham, Thomas Emslie Stewart, James Jordan Johnston   +3 more
wiley   +1 more source

Cognitive, Motor and Oculomotor Contributions to the Trail Making Test in Progressive Supranuclear Palsy

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by motor, oculomotor and cognitive impairments. Yet disentangling cognitive deficits from motor and oculomotor dysfunction remains a diagnostic and methodological challenge.
Indira Garcia‐Cordero, Mohsen Hadian, Juan Camilo Vargas‐Gonzalez, Marta Monteiro, David Gold, Abeer Khoja, Alonso Morales‐Rivero, Blas Couto, David Tang‐Wai, Susan Fox, Gabor G. Kovacs, Anthony E. Lang, Maria Carmela Tartaglia   +12 more
wiley   +1 more source

Orthostatic Myoclonus—Clinical and Electrophysiological Features in a Large Retrospective Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Orthostatic myoclonus is characterized by irregular, lower limb myoclonic bursts during stance and is a major cause of postural instability and falls. However, studies are limited, and little is known about its pathophysiology. Objectives We sought to define the clinical and electrophysiological features of orthostatic myoclonus in ...
Sai A. Nagaratnam, Niroshan Jeyakumar, Gobishan Jeyakumar, Florence Chang, Duncan Wilson, Paloma Becker, Hugo Morales‐Briceno, Neil Mahant, Victor S.C. Fung   +8 more
wiley   +1 more source

When Tics and Autism Meet: Phenomenology, Severity, and Treatment Patterns

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Tic disorders frequently co‐occur with neurodevelopmental conditions, including autism spectrum disorder (ASD). However, the impact of ASD on tic phenomenology, severity, and treatment patterns remains incompletely understood. Objectives To compare clinical characteristics, tic phenomenology, severity, and treatment patterns in ...
Fatimah Aldurayhim, Davide Martino, Justyna R. Sarna, Tamara Pringsheim   +3 more
wiley   +1 more source

Responding With Evidence and Access for Childhood Headaches (REACH) study: A comparative effectiveness trial of cognitive behavioral therapy monotherapy versus combined cognitive behavioral therapy-pharmacotherapy with amitriptyline for the prevention of childhood migraine-The study protocol. [PDF]

Headache
Abstract Migraine is one of the most common chronic health problems in children and adolescents, resulting in high levels of functional disability. Symptoms frequently persist into and impact the course of adulthood for affected individuals. Current practice recommendations include a combined therapy approach of preventive medication and cognitive ...
Feldman ECH, Ernst MM, Marzouk MA, Gibler RC, Reidy BL, Chamberlin LA, Kirschman M, Peugh J, Kabbouche M, LeCates SL, Kacperski J, Saunders JA, Hershey AD, Yonker ME, Szperka CL, Gelfand AA, Powers SW, REACH Study Investigators.   +17 more
europepmc   +2 more sources