Results 11 to 20 of about 26,582 (250)

Amitriptyline prescribing in public sector healthcare facilities in the Western Cape, South Africa.

PLoS ONE, 2020
BackgroundInappropriate medication use is a major patient safety concern, especially for the elderly population. Amitriptyline is widely used in primary care in South Africa and a cross-sectional study found that amitriptyline was prescribed potentially ...
Renier Coetzee, Yasmina Johnson, Johan van Niekerk, Mosedi Namane   +3 more
doaj   +1 more source

The Effectiveness and Adverse Events of Amitriptyline and Aripiprazole in Very Elderly Patients With BMS

Frontiers in Pain Research, 2022
Burning mouth syndrome (BMS) is defined by chronic oral burning sensations without any corresponding abnormalities. Besides amitriptyline, aripiprazole has been reported as a possible medication to manage BMS.
Motoko Watanabe, Chihiro Takao, Zhenyan Liu, Gayatri Nayanar, Takayuki Suga, Chaoli Hong, Trang Thi Huyen Tu, Trang Thi Huyen Tu, Tatsuya Yoshikawa, Miho Takenoshita, Haruhiko Motomura, Takahiko Nagamine, Akira Toyofuku   +12 more
doaj   +1 more source

Key Role of the Membrane Trafficking of Nav1.5 Channel Protein in Antidepressant-Induced Brugada Syndrome

Frontiers in Physiology, 2018
Anti-depressant treatment has been found to be associated with the development of Brugada syndrome (BrS) through poorly defined mechanisms. Herein, this study aimed to explore the molecular basis for amitriptyline-induced BrS.
Xi Chen, Xi Chen, Chao Zhu, Hao Zhou, Yu Zhang, Zhongqi Cai, Honglin Wu, Xiaomeng Ren, Lei Gao, Jiancheng Zhang, Yang Li   +10 more
doaj   +1 more source

Correlation between Amitriptyline-Induced Cardiotoxic Effects and Cardiac S100b Protein in Isolated Rat Hearts

Balkan Medical Journal, 2016
Background: Amitriptyline is an important cause of mortality due to its cardiovascular toxicity. Aims: To investigate the changes in levels of cardiac S100b protein on amitriptyline-induced cardiotoxicity and also to examine the correlation between ...
Nil Hocaoğlu, Nergis Murat, Serap Cilaker Mıcılı, Burç Aydın, Bekir Uğur Ergür, Şule Kalkan   +5 more
doaj   +1 more source

Effects of Adding Dexmedetomidine to Amitriptyline on Sciatic Nerve Blockadge in Rats

Medicine Science, 2013
Neurotoxic effects of amitriptyline which is a tricyclic antidepressant limit its use as a local anesthetic. In this study, comparing the effect of combination of different amitrptyline doses with dexmedetomidine on block initiation and termination time ...
Mahmut Durmus, Mukadder Sanli, Erdogan Ozturk, Aytac Yucel, Nurcin Gulhas, M. Ozcan Ersoy   +5 more
doaj   +1 more source

Percutaneous electrical nerve field stimulation compared to standard medical therapy in adolescents with functional abdominal pain disorders

Frontiers in Pain Research, 2023
IntroductionStandard medical therapy (SMT) in children with functional abdominal pain disorders (FAPD) includes cyproheptadine and amitriptyline. While percutaneous electrical nerve field stimulation (PENFS) has shown benefit, no study has compared ...
Neha R. Santucci, Neha R. Santucci, Rashmi Sahay, Khalil I. El-Chammas, Khalil I. El-Chammas, Kahleb Graham, Kahleb Graham, Mikaela Wheatley, Mikaela Wheatley, Madeleine Vandenbrink, Jennifer Hardy, Lin Fei   +11 more
doaj   +1 more source

The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats

Clinics, 2010
OBJECTIVE: The present study was designed to further investigate the effect of amitriptyline, a classical tricyclic antidepressant, on carrageenan-induced paw edema in rats. METHODS: First, amitriptyline was administered intraperitoneally (i.p.) at doses
Valiollah Hajhashemi, Hossein Sadeghi, Mohsen Minaiyan, Ahmad Movahedian, Ardeshir Talebi   +4 more
doaj   +1 more source

A Comparative Analysis of Amytripiline, Flunnarazine and Topiramate in the treatment of Primary Headache

Nepal Journal of Neuroscience, 2021
Introduction Primary headache disorder, characterized by recurrent headache is the most prevalent disease leading to widespread ill health and impaired quality of life.
Babu Ram Pokharel, Gopal Raman Sharma, Prabhaw Upadhyaya, Samip Jung Budhathoki, Santosh Thapa, Jyoti Koirala   +5 more
doaj   +1 more source

Repeated Administration of Amitriptyline Reduces Oxaliplatin-Induced Mechanical Allodynia in Rats

Journal of Pharmacological Sciences, 2012
Oxaliplatin is a key drug in the treatment of colorectal cancer, but it causes acute and chronic neuropathies in patients. Amitriptyline has widely been used in patients with painful neuropathy.
Hikaru Sada, Nobuaki Egashira, Soichiro Ushio, Takehiro Kawashiri, Masafumi Shirahama, Ryozo Oishi   +5 more
doaj   +1 more source

Effect of herb-drug interactions of Bacopa monnieri Linn. (Brahmi) formulation on the pharmacokinetics of amitriptyline in rats

Brazilian Journal of Pharmaceutical Sciences, 2018
Interactions between herbs and drugs may increase or decrease the pharmacological or toxicological effects of either component. Experimental data on the pharmacokinetic interactions between herbal products and drugs are limited.
Fowad Khurshid, Jeyabalan Govindasamy, Habibullah Khalilullah, Mohammed Shivli Nomani, Mudassar Shahid, Md Ruhal Ain, Mohammad Sultan Alsultan   +6 more
doaj   +1 more source