Results 11 to 20 of about 42,887 (227)

From Redox Imbalance to Tissue Injury: Insights Into Antidepressant Drug Amitriptyline Effects on Salivary Glands. [PDF]

Cell Biochem Funct
ABSTRACT This study aimed to investigate the effects of amitriptyline administration on the salivary glands and saliva of rats. Twenty‐eight male Wistar rats (60 days old) were divided into two groups (n = 14 per group): control and amitriptyline‐treated (10 mg/kg/day for 30 days).
Pereira CDS, Souza-Monteiro D, Né YGS, Cruz JND, Santos VRND, Varela ELP, Percário S, Bittencourt LO, Chaves-Neto AH, Lima RR.   +9 more
europepmc   +2 more sources

Amitriptyline Induced Life-Threatening Steven-Johnson Syndrome: Case Report. [PDF]

Clin Case Rep
ABSTRACT Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and carbamazepine are commonly implicated.
Dereje WM, Yalew L, Tafesse N, Getachew TG.   +3 more
europepmc   +2 more sources

The Effectiveness and Adverse Events of Amitriptyline and Aripiprazole in Very Elderly Patients With BMS

Frontiers in Pain Research, 2022
Burning mouth syndrome (BMS) is defined by chronic oral burning sensations without any corresponding abnormalities. Besides amitriptyline, aripiprazole has been reported as a possible medication to manage BMS.
Motoko Watanabe, Chihiro Takao, Zhenyan Liu, Gayatri Nayanar, Takayuki Suga, Chaoli Hong, Trang Thi Huyen Tu, Trang Thi Huyen Tu, Tatsuya Yoshikawa, Miho Takenoshita, Haruhiko Motomura, Takahiko Nagamine, Akira Toyofuku   +12 more
doaj   +1 more source

Biochemical and immunocytochemical studies of the testicular alteration caused by Amitriptyline in adult male rat [PDF]

Journal of Bioscience and Applied Research, 2018
Amitriptyline is one of the first reference tricyclic antidepressants (TCAs) with sedative and analgesic properties. This study aimed to investigate the testicular indices that influenced by amitriptyline treatment and examined it by biochemical ...
Ehab Tousson, Somia Zaki, Ezar Hafez, Amani Gad   +3 more
doaj   +1 more source

Acetylcholine Esterase Gene Expression in Salivary Glands of Albino Rats after Treatment with amitriptyline or/and Ashwagandha

Journal of Applied Veterinary Sciences, 2023
Acetylcholinesterase is required as an enzyme to counteract the effects of acetylcholine. The aim of the study is to assess how amitriptyline and Ashwagandha affect the acetylcholinesterase gene in rat salivary glands.
Ismail R. Idrees , Ghada A. Taqa , Saba Kh. A. Ibrahim   +2 more
doaj   +1 more source

Key Role of the Membrane Trafficking of Nav1.5 Channel Protein in Antidepressant-Induced Brugada Syndrome

Frontiers in Physiology, 2018
Anti-depressant treatment has been found to be associated with the development of Brugada syndrome (BrS) through poorly defined mechanisms. Herein, this study aimed to explore the molecular basis for amitriptyline-induced BrS.
Xi Chen, Xi Chen, Chao Zhu, Hao Zhou, Yu Zhang, Zhongqi Cai, Honglin Wu, Xiaomeng Ren, Lei Gao, Jiancheng Zhang, Yang Li   +10 more
doaj   +1 more source

Correlation between Amitriptyline-Induced Cardiotoxic Effects and Cardiac S100b Protein in Isolated Rat Hearts

Balkan Medical Journal, 2016
Background: Amitriptyline is an important cause of mortality due to its cardiovascular toxicity. Aims: To investigate the changes in levels of cardiac S100b protein on amitriptyline-induced cardiotoxicity and also to examine the correlation between ...
Nil Hocaoğlu, Nergis Murat, Serap Cilaker Mıcılı, Burç Aydın, Bekir Uğur Ergür, Şule Kalkan   +5 more
doaj   +1 more source

Effects of Adding Dexmedetomidine to Amitriptyline on Sciatic Nerve Blockadge in Rats

Medicine Science, 2013
Neurotoxic effects of amitriptyline which is a tricyclic antidepressant limit its use as a local anesthetic. In this study, comparing the effect of combination of different amitrptyline doses with dexmedetomidine on block initiation and termination time ...
Mahmut Durmus, Mukadder Sanli, Erdogan Ozturk, Aytac Yucel, Nurcin Gulhas, M. Ozcan Ersoy   +5 more
doaj   +1 more source

Percutaneous electrical nerve field stimulation compared to standard medical therapy in adolescents with functional abdominal pain disorders

Frontiers in Pain Research, 2023
IntroductionStandard medical therapy (SMT) in children with functional abdominal pain disorders (FAPD) includes cyproheptadine and amitriptyline. While percutaneous electrical nerve field stimulation (PENFS) has shown benefit, no study has compared ...
Neha R. Santucci, Neha R. Santucci, Rashmi Sahay, Khalil I. El-Chammas, Khalil I. El-Chammas, Kahleb Graham, Kahleb Graham, Mikaela Wheatley, Mikaela Wheatley, Madeleine Vandenbrink, Jennifer Hardy, Lin Fei   +11 more
doaj   +1 more source

The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats

Clinics, 2010
OBJECTIVE: The present study was designed to further investigate the effect of amitriptyline, a classical tricyclic antidepressant, on carrageenan-induced paw edema in rats. METHODS: First, amitriptyline was administered intraperitoneally (i.p.) at doses
Valiollah Hajhashemi, Hossein Sadeghi, Mohsen Minaiyan, Ahmad Movahedian, Ardeshir Talebi   +4 more
doaj   +1 more source