Results 11 to 20 of about 27,203 (239)

Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways

open access: yesRespiratory Research, 2023
Introduction The standard therapy for bronchial asthma consists of combinations of acute (short-acting ß2-sympathomimetics) and, depending on the severity of disease, additional long-term treatment (including inhaled glucocorticoids, long-acting ß2 ...
Paulina Hempel   +11 more
doaj   +1 more source

Amitriptyline prescribing in public sector healthcare facilities in the Western Cape, South Africa.

open access: yesPLoS ONE, 2020
BackgroundInappropriate medication use is a major patient safety concern, especially for the elderly population. Amitriptyline is widely used in primary care in South Africa and a cross-sectional study found that amitriptyline was prescribed potentially ...
Renier Coetzee   +3 more
doaj   +1 more source

Acetylcholine Esterase Gene Expression in Salivary Glands of Albino Rats after Treatment with amitriptyline or/and Ashwagandha

open access: yesJournal of Applied Veterinary Sciences, 2023
Acetylcholinesterase is required as an enzyme to counteract the effects of acetylcholine. The aim of the study is to assess how amitriptyline and Ashwagandha affect the acetylcholinesterase gene in rat salivary glands.
Ismail R. Idrees   +2 more
doaj   +1 more source

Biochemical and immunocytochemical studies of the testicular alteration caused by Amitriptyline in adult male rat [PDF]

open access: yesJournal of Bioscience and Applied Research, 2018
Amitriptyline is one of the first reference tricyclic antidepressants (TCAs) with sedative and analgesic properties. This study aimed to investigate the testicular indices that influenced by amitriptyline treatment and examined it by biochemical ...
Ehab Tousson   +3 more
doaj   +1 more source

The Effectiveness and Adverse Events of Amitriptyline and Aripiprazole in Very Elderly Patients With BMS

open access: yesFrontiers in Pain Research, 2022
Burning mouth syndrome (BMS) is defined by chronic oral burning sensations without any corresponding abnormalities. Besides amitriptyline, aripiprazole has been reported as a possible medication to manage BMS.
Motoko Watanabe   +12 more
doaj   +1 more source

Key Role of the Membrane Trafficking of Nav1.5 Channel Protein in Antidepressant-Induced Brugada Syndrome

open access: yesFrontiers in Physiology, 2018
Anti-depressant treatment has been found to be associated with the development of Brugada syndrome (BrS) through poorly defined mechanisms. Herein, this study aimed to explore the molecular basis for amitriptyline-induced BrS.
Xi Chen   +10 more
doaj   +1 more source

Correlation between Amitriptyline-Induced Cardiotoxic Effects and Cardiac S100b Protein in Isolated Rat Hearts

open access: yesBalkan Medical Journal, 2016
Background: Amitriptyline is an important cause of mortality due to its cardiovascular toxicity. Aims: To investigate the changes in levels of cardiac S100b protein on amitriptyline-induced cardiotoxicity and also to examine the correlation between ...
Nil Hocaoğlu   +5 more
doaj   +1 more source

Effects of Adding Dexmedetomidine to Amitriptyline on Sciatic Nerve Blockadge in Rats

open access: yesMedicine Science, 2013
Neurotoxic effects of amitriptyline which is a tricyclic antidepressant limit its use as a local anesthetic. In this study, comparing the effect of combination of different amitrptyline doses with dexmedetomidine on block initiation and termination time ...
Mahmut Durmus   +5 more
doaj   +1 more source

Percutaneous electrical nerve field stimulation compared to standard medical therapy in adolescents with functional abdominal pain disorders

open access: yesFrontiers in Pain Research, 2023
IntroductionStandard medical therapy (SMT) in children with functional abdominal pain disorders (FAPD) includes cyproheptadine and amitriptyline. While percutaneous electrical nerve field stimulation (PENFS) has shown benefit, no study has compared ...
Neha R. Santucci   +11 more
doaj   +1 more source

The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats

open access: yesClinics, 2010
OBJECTIVE: The present study was designed to further investigate the effect of amitriptyline, a classical tricyclic antidepressant, on carrageenan-induced paw edema in rats. METHODS: First, amitriptyline was administered intraperitoneally (i.p.) at doses
Valiollah Hajhashemi   +4 more
doaj   +1 more source

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