Results 31 to 40 of about 36,705 (184)

SODAS: Surveillance of Drugs of Abuse Study [PDF]

, 2017
Objective: Novel Psychoactive Substance (NPS) as a form of recreational drug use has become increasingly popular. There is a paucity of information with regards the prevalence and clinical sequalae of these drugs.
Bloeck, Felix, Ireland, Alastair, Lowe, David J., Stevenson, Richard, Torrance, Hazel   +4 more
core   +1 more source

Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study.

Gastroenterology, 2015
BACKGROUND & AIMS Antidepressants are frequently prescribed to treat functional dyspepsia (FD), a common disorder characterized by upper abdominal symptoms, including discomfort or postprandial fullness.
N. Talley, N. Talley, G. Locke, Yuri A Saito, Ann E. Almazar, E. Bouras, C. Howden, B. Lacy, J. DiBaise, C. Prather, B. Abraham, H. El‐Serag, P. Moayyedi, L. Herrick, L. Szarka, M. Camilleri, F. Hamilton, C. Schleck, Katherine E. Tilkes, A. Zinsmeister   +19 more
semanticscholar   +1 more source

Some t-tests for N-of-1 trials with serial correlation

, 2019
N-of-1 trials allow inference between two treatments given to a single individual. Most often, clinical investigators analyze an individual's N-of-1 trial data with usual t-tests or simple nonparametric methods.
Landes, Reid D., Tang, Jillian
core   +1 more source

Environmentally friendly analysis of emerging contaminants by pressurized hot water extraction-stir bar sorptive extraction-derivatization and gas chromatography-mass spectrometry [PDF]

, 2013
This work describes the development, optimiza- tion, and validation of a new method for the simultaneous determination of a wide range of pharmaceuticals (beta- blockers, lipid regulators ...
A Azzouz, A Cottell, A Göbel, A Peck, A Saleh, A Shrivastava, ARM Silva, E Baltussen, E Concha-Graña, E Pérez-Carrera, Eduardo González-Mazo, F Pomati, FJ Camino-Sánchez, J Xu, JB Quintana, JC Durán-Alvarez, KJ Bisceglia, M Kawaguchi, M Kuster, M Petrovic, M Winkler, Marina G. Pintado-Herrera, MG Cantwell, MJ Gomez, N Jonkers, N Ramírez, PA Lara-Martín, PA Lara-Martín, Pablo A. Lara-Martín, R Rodil, SB Hawthorne, SL Rice, T Kupper, VM León, WM Liu, Y Valcarcel   +35 more
core   +2 more sources

Amitriptyline inhibits the MAPK/ERK and CREB pathways and proinflammatory cytokines through A3AR activation in rat neuropathic pain models

Korean Journal of Anesthesiology, 2018
Background The pain-relief properties of tricyclic antidepressants can be attributed to several actions. Recent observations suggest that adenosine is involved in the antinociceptive effect of amitriptyline.
Y. Kim, So-Young Kwon, H. S. Jung, Yoojung Park, Yong Shin Kim, J. In, J. Choi, Jin A. Kim, J. Joo   +8 more
semanticscholar   +1 more source

Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants [PDF]

, 1996
Background: This study investigated differences in cognitive performance between middle-aged adults with and without a lifetime history of mood disorder features, adjusting for a range of potential confounders.
Cullen, B., Deary, I..J., Evans, J.J., Gallacher, J., Mackay, D.F., Martin, D., McIntosh, A., Nicholl, B.I., Pell, J.P., Smith, D.J., Ul-Haq, Z.   +10 more
core   +2 more sources

Initiation of Psychotropic Medication after Partner Bereavement: A Matched Cohort Study [PDF]

, 2013
Background Recent changes to diagnostic criteria for depression in DSM-5 remove the bereavement exclusion, allowing earlier diagnosis following bereavement.
A Bourke, AL Forte, Christina R. Victor, Derek G. Cook, DM Fick, DS Davydow, E Bui, EL Fosbøl, G Brown, Iain M. Carey, J Glass, J Möller, J Warner, James Coyne, JC Wakefield, JD Lewis, JM Cook, M Stroebe, ME Charlson, R Mojtabai, S Zisook, S Zisook, SM Shah, SM Shah, SM Shah, Stephen DeWilde, Sunil M. Shah, Tess Harris   +27 more
core   +3 more sources

Update on medication-overuse headache and its treatment [PDF]

, 2015
OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA, MARTELLETTI, Paolo, Mitsikostas DD   +2 more
core   +1 more source

Experimental pharmacological research regarding some new quinazolin-4-ones derivatives [PDF]

, 2019
A series of new compounds with quinazolin-4-one structure, synthesized by the Pharmaceutical Chemistry Department of the Faculty of Pharmacy of the University of Medicine and Pharmacy “Carol Davila” Bucharest, was studied.
Bratu, Mihaela, Chiriță, Cornel, Chiriță, Ileana C, Limban, Carmen, Marineci, Cristina D, Negreș, Simona, Nuță, Diana C, Zbârcea, Cristina E, Ștefănescu, Emil   +8 more
core   +1 more source

Tricyclic antidepressant amitriptyline inhibits autophagic flux and prevents tube formation in vascular endothelial cells

Basic & Clinical Pharmacology & Toxicology, 2018
Amitriptyline is a tricyclic antidepressant and an inhibitor of lysosomal acid sphingomyelinase (ASM). Amitriptyline is well known for its cardiovascular side effects and toxicity in psychiatric patients.
Ying-Chao Guan, Xiang Li, M. Umetani, K. Boini, Pin-Lan Li, Yang Zhang   +5 more
semanticscholar   +1 more source