Results 41 to 50 of about 44,071 (294)
Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]
Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Born, Christoph+4 more
core +1 more source
Calcium channel blocker-induced depression: a case report from South India
Flunarizine is a cerebro-selective calcium channel blocker, commonly prescribed for migraine prophylaxis and is considered as non-inferior to propranolol to reduce the frequency of migraine attacks.
Sumana Gundam, Keya Das
doaj +1 more source
Chronic pain and sleep have a bidirectional relationship that promotes a vicious circle making chronic pain more difficult to treat. Therefore, pain and sleep should be treated simultaneously.
Hisakatsu Ito+5 more
doaj +1 more source
Pharmaceuticals such as antidepressants are designed to be bioactive at low concentrations. According to their mode of action, they can also influence non-target organisms due to the phylogenetic conservation of molecular targets.
Hannah Schmieg+7 more
doaj +1 more source
Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants [PDF]
Background: This study investigated differences in cognitive performance between middle-aged adults with and without a lifetime history of mood disorder features, adjusting for a range of potential confounders.
Cullen, B.+10 more
core +2 more sources
Objectives: The main objective is to compare efficacy and safety of pregabalin and amitriptyline monotherapy with their low-dose combination in patients of neuropathic pain (NeuP).
Sourav Chakrabarty+5 more
doaj +1 more source
The Effect of Amitriptyline on Biomarkers Associated with Brain Health and Drug Metabolism [PDF]
The Effect of Amitriptyline on Biomarkers Associated with Brain Health and Drug Metabolism Ashana Jackson, Dept. of Psychology, Bukola Odeniyi, and Omar Hassan, with Dr. Elvin T.
Hassan, Omar+2 more
core +1 more source
Pharmacology and relevant drug interactions of metamizole
Metamizole is a frequently prescribed analgesic because of its favourable benefit/risk ratio compared with classic NSAIDs. However, increasing research shows that metamizole displays several drug interactions that are relevant to clinical practice. We reviewed the literature to summarize the pharmacology and most clinically relevant drug interactions ...
David J. Brinkman+3 more
wiley +1 more source
Some t-tests for N-of-1 trials with serial correlation
N-of-1 trials allow inference between two treatments given to a single individual. Most often, clinical investigators analyze an individual's N-of-1 trial data with usual t-tests or simple nonparametric methods.
Landes, Reid D., Tang, Jillian
core +1 more source
In pediatric oncology, pharmacogenetic guidelines are underutilized and the potential impact of pre‐emptive pharmacogenetic screening remains largely unexplored despite this field's need for individualized approaches. While comprehensive pharmacogenetic guidelines are not yet available for all anticancer drugs, evidence‐based recommendations exist for ...
Emma C. Bernsen+12 more
wiley +1 more source