Results 41 to 50 of about 27,203 (239)

A Retrospective Analysis Into the Effect of Punch Grafts in Patients With Chronic Ulcers of the Lower Leg

JEADV Clinical Practice, EarlyView.
Punch grafting was retrospectively evaluated in patients with chronic lower leg ulcers treated at Erasmus MC between 2018 and 2023. Median pain scores significantly decreased after 6 weeks. Opioid use declined and 30% of patients no longer required analgesics. Complete wound closure was achieved in 7% of cases.
M. van Zanten, J. E. Geskes, M. M. E. Thung, P. Velthuis, C. van Montfrans   +4 more
wiley   +1 more source

Amitriptyline induced cervical dystonia

Journal of the Scientific Society, 2016
Tricyclic antidepressants (TCAs), such as amitriptyline, have many side effects. But extrapyramidal tract symptom is an uncommon side effect of these drugs. Here, we report a case of a 28-year-old male who is suffering from amitriptyline induced cervical
Shivanand B Hiremath, Mahesh Desai
doaj   +1 more source

Comparing the efficacy and safety of duloxetine and amitriptyline in the treatment of fibromyalgia: overview of systematic reviews

Advances in Rheumatology, 2020
Background Duloxetine and amitriptyline are antidepressants used in the treatment of fibromyalgia. In published systematic reviews, there is no agreement about which drug is more effective and safer.
Áurea Dias de Farias, Luciana Eberle, Tânia Alves Amador, Tatiane da Silva Dal Pizzol   +3 more
doaj   +1 more source

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT

Health Technology Assessment, 2022
Background: The mainstay of treatment for diabetic peripheral neuropathic pain is pharmacotherapy, but the current National Institute for Health and Care Excellence guideline is not based on robust evidence, as the treatments and their combinations have ...
Solomon Tesfaye, Gordon Sloan, Jennifer Petrie, David White, Mike Bradburn, Tracey Young, Satyan Rajbhandari, Sanjeev Sharma, Gerry Rayman, Ravikanth Gouni, Uazman Alam, Steven A Julious, Cindy Cooper, Amanda Loban, Katie Sutherland, Rachel Glover, Simon Waterhouse, Emily Turton, Michelle Horspool, Rajiv Gandhi, Deirdre Maguire, Edward Jude, Syed Haris Ahmed, Prashanth Vas, Christian Hariman, Claire McDougall, Marion Devers, Vasileios Tsatlidis, Martin Johnson, Didier Bouhassira, David L Bennett, Dinesh Selvarajah   +31 more
doaj   +1 more source

Considerations and Tips for Promoting Skin Barrier Maintenance and Quality of Life in Patients With Diabetes Mellitus: An Expert Consensus

JEADV Clinical Practice, EarlyView.
ABSTRACT Skin changes such as xerosis and pruritus are common complications among diabetes patients and may lead to serious adverse events such as diabetic foot syndrome and amputations. Evidence suggests that daily application of optimal skincare, including gentle cleansers and moisturizers, may help improve skin barrier function, preventing ...
Robert S. Kirsner, Anneke Andriessen, Brian Berman, Natasha Mesinkovska, Heather Woolery‐Lloyd, Lawrence Schachner   +5 more
wiley   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke, Lahiru Wedasingha, Magnus Rydberg   +2 more
wiley   +1 more source

Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study

Arquivos de Neuro-Psiquiatria, 2014
To compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine. Method Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were ...
Michelle Dias Santos Santiago, Deusvenir de Souza Carvalho, Alberto Alain Gabbai, Mariana Machado Pereira Pinto, Andrea Regina Correa Moutran, Thais Rodrigues Villa   +5 more
doaj   +1 more source

Examination and characterisation of the effect of amitriptyline therapy for chronic neuropathic pain on neuropeptide and proteomic constituents of human cerebrospinal fluid

Brain, Behavior, & Immunity - Health, 2021
Introduction: Amitriptyline is prescribed to reduce the intensity of chronic neuropathic pain. There is a paucity of validated in vivo evidence in humans regarding amitriptyline’s mechanism of action.
Jonathan Royds, Hilary Cassidy, Melissa J. Conroy, Margaret R. Dunne, Joanne Lysaght, Connail McCrory   +5 more
doaj   +1 more source

Anticholinergic Burden and Botulinum Toxin Needs after Deep Brain Stimulation in Adult and Pediatric Patients with Dystonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Anticholinergic medications and botulinum neurotoxin injections are established treatments for dystonia, yet they carry potential side effects and practical challenges. Deep brain stimulation (DBS) is offered in case of poor response to these approaches.
Marcela A. Montiel, Alessandro Magliozzi, Wei Kang Lim, Carolina Gorodetsky, George M. Ibrahim, Alfonso Fasano   +5 more
wiley   +1 more source

A Review of NIDDK‐Funded Studies of Urological Chronic Pain Conditions

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction This review highlights NIDDK‐funded clinical research studies focused on interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods Since 1987, the NIDDK has funded numerous cohort studies, epidemiologic studies, and clinical trials for these conditions.
J. Quentin Clemens
wiley   +1 more source