Results 131 to 140 of about 219,440 (288)

Isolation of Anammoxosomes From the Aggregate Culture of Ca. Brocadia Sapporoensis and Assembly of Ladderane Liposomes

open access: yesBiotechnology and Bioengineering, EarlyView.
Ladderane lipids in anammox bacteria can find use in artificial liposomes for drug delivery. This study developed the isolation of ladderane‐rich anammoxosome organelles from previously challenging aggregate mixed culture of Ca. Brocadia sapporoensis.
Tomáš Podzimek   +12 more
wiley   +1 more source

IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML

open access: yesOncoImmunology, 2018
Treatment for acute myeloid leukemia (AML) remains suboptimal and many patients remain refractory or relapse upon standard chemotherapy based on nucleoside analogs plus anthracyclines.
Belen Lopez-Millan   +19 more
doaj   +1 more source

A case of M-BCR-rearranged, Philadelphia-positive AML that relapsed as chronic phase CML [letter] [PDF]

open access: bronze, 1990
Gareth J. Morgan   +5 more
openalex   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

open access: yesCancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai   +6 more
wiley   +1 more source

Peptidomimetics Targeting the Amyloidogenicity of Nucleophosmin 1 Mutations in Acute Myeloid Leukemia

open access: yesChemBioChem, EarlyView.
Previous studies reveal an unexpected tendency for amyloid aggregation in specific regions of the C‐terminal domain (CTD) of nucleophosmin 1 (NPM1), a nucleolar chaperone involved in acute myeloid leukemia (AML). Herein, several peptide analogs of NPM1264‐277 (amyloid core) with conservative substitutions are designed and evaluated through biophysical ...
Daniele Florio   +7 more
wiley   +1 more source

Angular Momentum Loss Mechanisms in Cataclysmic Variables below the Period Gap

open access: yes, 2011
Mass transfer in cataclysmic variables (CVs) is usually considered to be caused by angular momentum loss (AML) driven by magnetic braking and gravitational radiation (GR) above the period gap, and solely by GR below the period gap.
Andronov   +26 more
core   +1 more source

Antibacterial and antiviral activity of a highly efficient electrospun r‐PET nanofiber

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Since the COVID‐19 pandemic, the emergence of clean air has increased interest in developing antimicrobial air filters, targeting sterilization and public health concerns. Nanofibers are a promising approach due to their high efficiency in air filtration, while nanoparticles adhered to the fibre surfaces can improve safety due to the biocidal ...
Karine Machry   +8 more
wiley   +1 more source

Ubiquitin-specific peptidase 3 induces TPA-mediated leukemia cell differentiation via regulating H2AK119ub

open access: yesAnimal Cells and Systems, 2019
Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Owing to the chemotherapy associated side effects and toxicity, it is necessary to find a new mechanism, which can identify new potential therapeutic targets at the molecular ...
Yun-Cheol Chae   +4 more
doaj   +1 more source

AML in Adults

open access: yes
AbstractAML is a malignancy of hematopoietic immature precursors (myeloblasts) that accumulate in the BM at the expense of their normal counterparts. AML is increasingly being recognized as a heterogenous malignancy based on distinct disease biology and underlying cytogenetic and molecular profiles.
Versluis, Jurjen   +4 more
openaire   +1 more source

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