Cannabidiol stimulates AML-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner [PDF]
, 2015 Glioma stem-like cells (GSCs) correspond to a tumor cell subpopulation, involved in glioblastoma multiforme (GBM) tumor ini- tiation and acquired chemoresistance.
Amantini, Consuelo +7 more
core +2 more sources
Estimation Method of Relative Slip in Fretting Fatigue Contact by Digital Image Correlation
Metals, 2022 An experimental method that can quantify relative slip was developed using digital image correlation (DIC) in order to evaluate the sliding portion. The bridge-type test setup was designed to establish the fretting contact condition.
Yue Su +7 more
doaj +1 more source
Illusory rotations in the haptic perception of moving spheres and planes [PDF]
, 2014 Recently, we have shown that a translating bar on which blindfolded participants position their hand is perceived as also rotating. Here, we investigated whether such an illusory rotation would also be found if a sphere or a plane (i.e.
AL Kaas +11 more
core +1 more source
Nondestructive Surface Crack Detection of Laser-Repaired Components by Laser Scanning Thermography
Applied Sciences, 2022 As a revolutionary new technique, laser-engineered net shaping (LENS) is a layer additive manufacturing process that enables accurate, rapid and automatic repair of industrial component damage.
Chuanqing Geng +4 more
doaj +1 more source
NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival [PDF]
, 2014 Transcription factor NRF2 is an important regulator of oxidative stress. It is involved in cancer progression, and has abnormal constitutive expression in acute myeloid leukaemia (AML).
A Ooi +46 more
core +1 more source
MUC1-C drives myeloid leukaemogenesis and resistance to treatment by a survivin-mediated mechanism [PDF]
, 2018 Acute myeloid leukaemia (AML) is an aggressive haematological malignancy with an unmet need for improved therapies. Responses to standard cytotoxic therapy in AML are often transient because of the emergence of chemotherapy-resistant disease.
Anastasiadou, Eleni +20 more
core +1 more source
Programmable and robust static topological solitons in mechanical metamaterials
Nature Communications, 2019 Mechanical solitons are notoriously difficult to control. Here, the authors report a theoretical framework for programming static periodic topological solitons into a metamaterial, and demonstrate its implementation in real metamaterials computationally ...
Yafei Zhang +4 more
doaj +1 more source
A soft, bioinspired artificial lymphatic system for interactive ascites transfer
Bioengineering & Translational Medicine, 2023 Low‐flow removal of refractory ascites is critical to treating cirrhosis and digestive system tumor, and thus, commercial ascites pump emerged lately.
Peng Wang +7 more
doaj +1 more source
Numerical Simulation of the Cold-Start Process of Polymer Electrolyte Fuel Cell
Energies, 2023 In this study, the cold-start process of a polymer electrolyte fuel cell has been numerically investigated under various ambient temperatures and operating currents, ranging from subzero to 283 K.
Yazhou Chen +4 more
doaj +1 more source
The role of the proteasome in AML
Blood Cancer Journal, 2016 AbstractAcute myeloid leukemia (AML) is deadly hematologic malignancy. Despite a well-characterized genetic and molecular landscape, targeted therapies for AML have failed to significantly improve clinical outcomes. Over the past decade, proteasome inhibition has been demonstrated to be an effective therapeutic strategy in several hematologic ...
Zohar Sachs +2 more
openaire +3 more sources