Results 61 to 70 of about 219,440 (288)
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
Static vector solitons in a topological mechanical lattice
Communications PhysicsTopological solitons, renowned for their stability and particle-like collision behaviors, have sparked interest in developing macroscopic-scale information processing devices. However, the exploration of interactions between multiple topological solitons
Yuan Zhou +4 more
doaj +1 more source
Two-dimensional modeling of the self-limiting oxidation in silicon and tungsten nanowires
Theoretical and Applied Mechanics Letters, 2016 Self-limiting oxidation of nanowires has been previously described as a reaction- or diffusion-controlled process. In this letter, the concept of finite reactive region is introduced into a diffusion-controlled model, based upon which a two-dimensional ...
Mingchao Liu +5 more
doaj +1 more source
Nature Communications, 2023 Transmission electron microscopy is a pivotal instrument in materials and biological sciences due to its ability to provide local structural and spectroscopic information on a wide range of materials.
Jonathan J. P. Peters +6 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.Previous studies on additive manufacturing primarily focus on the mechanical properties of as‐printed components. In the present work, researchers explore the potential of employing novel thermomechanical postprocessing techniques to improve the microstructure after printing.
Radim Kocich +3 more
wiley +1 more source
p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia [PDF]
, 2011 Suppression of apoptosis by TP53 mutation contributes to resistance of acute myeloid leukemia (AML) to conventional cytotoxic treatment. Using differentiation to induce irreversible cell cycle exit in AML cells could be a p53-independent treatment ...
Anjali Advani +15 more
core +2 more sources
Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Gene rearrangements in bone marrow cells of patients with acute myelogenous leukemia [PDF]
, 2000 At diagnosis, clonal gene rearrangement probes {[}retinoic acid receptor (RAR)-alpha, major breakpoint cluster region (M-bcr), immunoglobulin (Ig)-JH, T cell receptor (TcR)-beta, myeloid lymphoid leukemia (MLL) or cytokine genes (GM-CSF, G-CSF, IL-3 ...
Braun, S. +5 more
core +1 more source
Arginine addiction in AML [PDF]
Blood, 2015 In this issue of Blood, Miraki-Moud et al demonstrate that the majority of acute myeloid leukemias (AMLs) have low expression of argininosuccinate synthetase-1 (ASS1), rendering AML cell lines and primary AML blasts dependent on exogenous arginine and sensitized to arginine deprivation.
openaire +3 more sources
Advanced Functional Materials, EarlyView.A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao +8 more
wiley +1 more source