Results 1 to 10 of about 70,737 (298)
We report only the second published confirmed case of gynaecomastia caused by amlodipine (a dihydropyridine calcium channel blocker). Gynaecomastia developed in a 70-year-old male within 3 months of starting amlodipine, and symptoms resolved within 3 weeks of drug withdrawal suggesting a strong relationship between amlodipine and gynaecomastia in this ...
P G, Cornes, A C, Hole
openaire +3 more sources
Development and Evaluation of a Modified Fixed-Dose Combination Antihypertensive Tablet Containing S-Amlodipine Besylate: A Bioequivalence and Stability Study [PDF]
Background/Objectives: Fixed-dose combination (FDC) antihypertensive medications containing olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide are widely used for the treatment of essential hypertension.
Hyeon Woo Moon +2 more
doaj +2 more sources
Modern views on amlodipine and new S-amlodipine medications
The review presents the latest evidence on the calcium antagonist amlodipine, summarizing its mechanisms of action, its pleiotropic, endothelial function-related effects, and its anti-atherogenic activity.
M. V. Leonova
doaj +3 more sources
Risk of Acute Infections in New Users of Antihypertensive Drugs: An Observational Cohort Study [PDF]
Background Functional inhibitors of acid sphingomyelinase enhance human immune function in vitro. We compared the risk of acute infection in users of amlodipine, a functional inhibitor of acid sphingomyelinase, to users of other first‐line ...
Noah Aebi +4 more
doaj +2 more sources
L-type calcium channel blockers at therapeutic concentrations are not linked to CRAC channels and heart failure [PDF]
Amlodipine has been used as a front-line anti-hypertensive therapy for decades by virtue of blocking voltage-operated calcium channels with high affinity and specificity.
Gary S. Bird +6 more
doaj +2 more sources
We describe the case of a 24-year-old woman who intentionally ingested between 400 and 600 mg of amlodipine along with a large number of simvastatin and trazodone tablets.
Tapan, Patel +2 more
openaire +2 more sources
Amlodipine Overdose: Is High Dose Insulin Ready for Prime Time
Overdose of amlodipine, a dihydropyridine calcium channel blocker (CCB), is distinguished from other CCBs due to longer plasma half-life of 30 to 58 h.
Mary Jo S. Farmer +2 more
doaj +1 more source
In vitro and in silico studies and a systematic literature review of antiglycation properties of amlodipine. [PDF]
Dańkowska K +8 more
europepmc +3 more sources
Amlodipine reduces AngII-induced aortic aneurysms and atherosclerosis in hypercholesterolemic mice. [PDF]
The purpose of this study was to determine effects of amlodipine, a dihydropyridine calcium channel blocker, on development of angiotensin II (AngII)-induced vascular pathologies.Male LDL receptor -/- mice were infused with vehicle, amlodipine (5 mg/kg/d)
Xiaofeng Chen +8 more
doaj +1 more source
BackgroundPatients with chronic obstructive pulmonary disease (COPD) often have exercise intolerance. The prevalence of hypertension in COPD patients ranges from 39-51%, and β-blockers and amlodipine are commonly used drugs for these patients ...
Chou-Chin Lan +6 more
doaj +1 more source

