Results 121 to 130 of about 3,572 (239)
ChemBioChem, Volume 27, Issue 9, 14 May 2026.This review highlights advances in engineering Saccharomyces cerevisiae for the sustainable biocatalytic production of pharmaceutically relevant amines, amino alcohols, amino acids, and complex alkaloids. It focuses on strategies to increase productivity, including enhanced enzyme expression, cofactor regeneration, precursor channeling, pathway ...
Natalia Kwiatos +2 more
wiley +1 more source
Advanced Science, Volume 13, Issue 28, 18 May 2026.The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen +11 more
wiley +1 more source
Exploring the therapeutic potential of modern and ancestral phenylalanine/tyrosine ammonia-lyases as supplementary treatment of hereditary tyrosinemia. [PDF]
Sci Rep, 2020 Hendrikse NM +5 more
europepmc +1 more source
European Journal of Lipid Science and Technology, Volume 128, Issue 5, May 2026.Flax varieties differ in growth, oil quality, and beneficial compounds, but these differences are not always clear‐cut. In this study, 10 flax types were grown under the same conditions and compared for plant traits, natural compounds, and oil content. Some showed high omega‐3 and lignan levels, making them valuable for healthier foods and future crop ...
Mehmet Zeki Koçak, Sara Zare
wiley +1 more source
Detection of p-coumaric acid from cell supernatant using surface enhanced Raman scattering [PDF]
, 2017 Boisen, Anja +6 more
core +1 more source
Food Frontiers, Volume 7, Issue 3, May 2026.This study investigated the effects of salicylic acid (SA) application on the softening of grapes (Vitis vinifera L. ‘Red Globe’) during cold storage. The results demonstrated that SA treatment effectively delayed softening by regulating cell wall, cuticular wax, and phenylpropanoid metabolism.
Guihua Zeng +6 more
wiley +1 more source
Self‐Reported Health‐Related Quality of Life (HRQoL) in Adults With Urea Cycle Disorders
Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.ABSTRACT Multiple studies have assessed Health‐Related Quality of Life (HRQoL) in children with urea cycle disorders (UCDs); investigations in adults with the same disorders are rarer. Understanding the variables that modify self‐reported HRQoL has become increasingly important as novel treatments are developed, with clinically meaningful endpoints ...
Curtis R. Coughlin II +25 more
wiley +1 more source
Engineering enzymes for noncanonical amino acid synthesis [PDF]
, 2018 The standard proteinogenic amino acids grant access to a myriad of chemistries that harmonize to create life. Outside of these twenty canonical protein building blocks are countless noncanonical amino acids (ncAAs), either found in nature or created by ...
Almhjell, Patrick J. +2 more
core
Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.ABSTRACT Phenylketonuria (PKU) is a rare metabolic disorder causing elevated phenylalanine (PHE) levels requiring lifelong dietary or pharmacological management and regular monitoring. Current PHE monitoring methods, such as tandem mass spectrometry (FIA‐MS/MS), are laboratory and sample transport‐dependent, leading to delays in obtaining results. This
Corentin Gondrand +14 more
wiley +1 more source