Results 131 to 140 of about 3,572 (239)

Comparative Analysis of Dietary Patterns in Children With Phenylketonuria Phenotypes and Controls: Implications for Nutritional Status

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Individuals with phenylketonuria (PKU), caused by different variants of the phenylalanine hydroxylase gene, need to restrict their intake of phenylalanine. This study evaluated dietary patterns and physical activity levels in children with different PKU phenotypes compared to healthy controls. Eighty‐two children were recruited (22 classic PKU
Dolores Garcia‐Arenas   +9 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Pegvaliase in Japanese Adults With Phenylketonuria: Final Results of a Phase III Trial

open access: yesJIMD Reports, Volume 67, Issue 3, May 2026.
ABSTRACT Phenylketonuria (PKU) is an inborn error of metabolism leading to phenylalanine (Phe) accumulation and consequent neurological, neurocognitive, and psychiatric symptoms. Pegvaliase, a pegylated recombinant phenylalanine ammonia lyase that metabolizes Phe, effectively reduced blood Phe in phase III studies in the United States. This multicenter,
Yoko Nakajima   +6 more
wiley   +1 more source

Polyamine treatments: an effective strategy to improve crop yield and fruit colour and to preserve quality of ‘Mollar de Elche’ pomegranate fruit during storage at chilling temperatures

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 7, Page 4101-4112, May 2026.
Abstract BACKGROUND Climate change in Spain is altering the optimal conditions for producing high‐quality ‘Mollar de Elche’ pomegranate fruit, due to reduced colour development in husk and arils. In addition, the pomegranate requires storage above 7–10 °C, depending on cultivar, to preserve its quality because it is susceptible to chilling injury (CI ...
Jenifer Puente‐Moreno   +6 more
wiley   +1 more source

Engineering and biocatalytic applications of methylaspartate ammonia lyase:asymmetric synthesis of aspartic acid derivatives [PDF]

open access: yes, 2013
Nieuwe milieuvriendelijke syntheseroute voor niet-natuurlijke aminozuren Het onderzoek van Hans Raj heeft een nieuwe, schone en milieuvriendelijke syntheseroute opgeleverd voor verschillende niet-natuurlijke aminozuren die met de traditionele chemische ...
Raj, Hans
core  

Orthogonal Tri‐Modular Coiled‐Coil Assembly for Programmable Multi‐Cargo Display on Escherichia coli Nissle 1917

open access: yesSmall, Volume 22, Issue 28, 18 May 2026.
A tri‐specific scaffold cell (TriSC) platform is engineered to enable programmable, reversible, and multiplex surface assembly through orthogonal and spontaneous coiled‐coil interactions. Independent targeting and therapeutic nanobodies are modularly recruited onto bacterial surfaces, allowing tunable combinatorial functionality.
Yong Joon Cho   +3 more
wiley   +1 more source

The production of L- and D-phenylalanines using engineered phenylalanine ammonia lyases from Petroselinum crispum. [PDF]

open access: yesSci Rep, 2019
Tork SD   +7 more
europepmc   +1 more source

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers   +16 more
wiley   +1 more source

Perspectives for Advancing Biotechnological Succinic Acid Production

open access: yesMicrobial Biotechnology, Volume 19, Issue 5, May 2026.
Succinic acid is an important molecule for sustainable chemical manufacturing, but its industrial production faces high costs and sustainability challenges, which are linked to feedstocks and excessive acid/base consumption. This opinion explores production routes based on next‐generation feedstocks and low‐pH fermentations to inspire novel cost ...
Christoph Gunkel, Bastian Blombach
wiley   +1 more source

The Dual Role of Methyl Caffeate: Growth Inhibition of Pseudomonas syringae and Induction of Resistance to Bacterial Speck Disease in Tomato

open access: yesMolecular Plant Pathology, Volume 27, Issue 5, May 2026.
Methyl caffeate exhibits dual functionality against Pseudomonas syringae pv. tomato. It directly disrupts bacterial membrane integrity, induces reactive oxygen species accumulation, and inhibits flagellar motility and the type III secretion system. Concurrently, it primes plant defence by activating defence‐related gene expression and enzyme activities,
Yarui Yang   +11 more
wiley   +1 more source

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