Results 111 to 120 of about 15,149 (207)

Effects of Drug Policy Changes on Evolution of Molecular Markers of Plasmodium falciparum Resistance to Chloroquine, Amodiaquine, and Sulphadoxine-Pyrimethamine in the South West Region of Cameroon [PDF]

, 2018
Marcel N. Moyeh, Dieudonné Lemuh Njimoh, M.S. Evehe, Innocent Mbulli Ali, Akindeh M. Nji, Dominique N. Nkafu, Palmer Masumbe, Barbara Atogho‐Tiedeu, Valentine Ndikum, Wilfred Fon Mbacham   +9 more
openalex   +1 more source

Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial

, 2022
Steve M. Taylor, Sarah Korwa, Angie Wu, Cynthia L. Green, Betsy Freedman, Sheila Clapp, Joseph Kipkoech Kirui, Wendy Prudhomme O’Meara, Festus Njuguna   +8 more
openalex   +1 more source

Voacanga africana-artesunate and Voacanga africana-amodiaquine combinations as effective anti-plasmodial agents in mice

Scientific African
Background: Malaria is a global health problem due to its high incidence of morbidity and mortality, especially in children and pregnant women. However, the Plasmodium parasite frequently develops resistance to chemotherapy, triggering continuous ...
Daniel Ampomah Frimpong, Aliu Moomin, Samuel Asare Nkansah, Aaron Opoku Antwi, Abubakar Ibn Sidik, Paa Kofi Tawiah Adu-Gyamfi, Kwesi Boadu Mensah   +6 more
doaj   +1 more source

Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains.

, 2007
Piperaquine is being developed as a long-acting component in artemisinin combination therapies. It was highly active in vitro and drug interaction studies showed that dihydroartemisinin combinations with piperaquine, chloroquine, and amodiaquine were ...
Adagu, Ipemida S, Fivelman, Quinton L, Warhurst, David C   +2 more
core   +2 more sources

PBPK‐led assessment of antimalarial drugs as candidates for Covid‐19: Simulating concentrations at the site of action to inform repurposing strategies

Clinical and Translational Science
The urgent need for safe, efficacious, and accessible drug treatments to treat coronavirus disease 2019 (COVID‐19) prompted a global effort to evaluate drug repurposing opportunities.
Nada Abla, Lisa M. Almond, Jennifer J. Bonner, Naomi Richardson, Timothy N. C. Wells, Jörg J. Möhrle   +5 more
doaj   +1 more source

Artesunat-amodiakuin dan Klorokuin untuk Pengobatan Malaria Vivaks di Puskesmas Kopeta, Maumere, Nusa Tenggara Timur, 2007 [PDF]

, 2014
Indonesia merupakan negara endemis malaria yang merekomendasi Artemisinin-based Combination Therapy (ACT) untuk malaria Plasmodium vivax. Konfirmasi resistensi P.vivax terhadap kloroquin dan efikasi ACT perlu diteliti untuk mendukung kebijakan ...
Hasugian, A. R. (Armedy), Tjitra, E. (Emiliana)   +1 more
core  

Dihydroartemisinin-Piperaquine versus Artesunate-Amodiaquine: Superior Efficacy and Posttreatment Prophylaxis against Multidrug-Resistant Plasmodium falciparum and Plasmodium vivax Malaria

, 2007
Armedy Ronny Hasugian, Hermawan Purba, Enny Kenangalem, R. M. Wuwung, E. P. Ebsworth, R. Maristela, Pasi Penttinen, Ferdinand Laihad, Nicholas M. Anstey, Emiliana Tjitra, Ric N. Price   +10 more
openalex   +1 more source

Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso [PDF]

, 2015
Issaka Zongo, Paul Milligan, Yves Daniel Compaoré, Anyirékun Fabrice Somé, Brian Greenwood, Joel Tärning, Philip J. Rosenthal, Colin J. Sutherland, François Nosten, Jean‐Bosco Ouédraogo   +9 more
openalex   +1 more source

Short report: molecular markers associated with Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in the Democratic Republic of Congo. [PDF]

, 2006
Sulfadoxine-pyrimethamine (SP) is the first line antimalarial treatment in the Democratic Republic of Congo. Using polymerase chain reaction, we assessed the prevalence of mutations in the dihydrofolate reductase (dhfr) (codons 108, 51, 59) and ...
Bonnet, M, Cohuet, S, D'Alessandro, U, Guthmann, J P, Van Herp, M, Van Overmeir, C   +5 more
core   +2 more sources

Artesunate + amodiaquine and artesunate + sulphadoxine–pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine‐resistant haplotypes [PDF]

, 2006
Todd D. Swarthout, Ingrid V. van den Broek, G. Kayembe, Jacqui Montgomery, Hirva Pota, Cally Roper   +5 more
openalex   +1 more source