Systematic review of amodiaquine treatment in uncomplicated malaria
The Lancet, 1996 Opinion and policy over the use of amodiaquine for treating malaria vary. Amodiaquine is more palatable than chloroquine and may be more effective but serious adverse events have been reported in travellers taking it as prophylaxis. It is not recommended as first-line treatment.
Olliaro P. +6 more
openaire +4 more sources
Journal of Applied Sciences and Environmental Management, 2018 Cu (ll) and Co (II) complexes of amodiaquine hydrochloride and sulphamethazine (AMOSUF) have been prepared and characterized by elemental analysis, molar conductivity, FTIR and electronic spectroscopy.
E.A. Enemose, E.E. Akporhonor, B Kpomah
doaj +1 more source
Malaria Journal, 2008 Background Combination therapy has become a new paradigm in malaria treatment. Amodiaquine is a common partner drug in different malaria combination therapies used or investigated in sub-Saharan Africa, but data on its efficacy as a single drug are ...
Meissner Peter +4 more
doaj +1 more source
EFFECT OF AMODIAQUINE ON GASTRIC HISTAMINE METHYLTRANSFERASE AND ON HISTAMINE‐STIMULATED GASTRIC SECRETION [PDF]
, 1975 H. Barth, W. Lorenz, H. Troidl
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Knowledge, attitudes and practices of malaria control among communities from the health district of Forécariah in the Republic of Guinea, West Africa. [PDF]
, 2014 BACKGROUND & OBJECTIVES: Malaria is the leading cause of death in children under 5-yr of age in the Republic of Guinea. This study aimed at investigating the knowledge, attitudes and practices of malaria control in urban and rural communities in Guinea ...
Banek, Kristin +3 more
core +1 more source
The efficacy of halofantrine in the treatment of acute malaria in nonimmune travelers [PDF]
, 1992 A multicenter prospective trial was performed to investigate the efficacy and the tolerability of halofantrine in nonimmune patients with malaria imported from areas with drug-resistant falciparum parasites (mainly Africa).
Bock, H. L. +8 more
core +1 more source
Infection, Genetics and Evolution, 2007 Despite the pharmacodynamic advantages with artemisinin-based combination therapy (ACT) and some potentially opposite molecular mechanisms of tolerance to amodiaquine (AQ)/desethylamodiaquine (DEAQ) and artesunate (ART), there is a risk for rapid decay in efficacy if the two drugs are unable to ensure mutual prevention against a selection and spread of
Gabrielle Holmgren +6 more
openaire +3 more sources
Distribution of the cytochrome P450 CYP2C8*2 allele in Brazzaville, Republic of Congo
International Journal of Infectious Diseases, 2019 Background: Cytochrome P450 (CYP) enzymes are essential in the metabolism of most drugs used today. Single nucleotide polymorphism(s) occurring in CYP genes can adversely affect drug pharmacokinetics, efficacy, and safety. Individuals carrying the CYP2C8*
Simon Marie Peko +6 more
doaj +1 more source
Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component [PDF]
, 1996 Shaun R. Hawley +5 more
openalex +1 more source
Safety of a fixed-dose combination of artesunate and amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in real-life conditions of use in Côte d’Ivoire [PDF]
, 2017 Additional file 2.
Abouo Franklin Nguessan +9 more
core +3 more sources