Evaluating the effectiveness and cost-effectiveness of integrating mass drug administration for helminth control with seasonal malaria chemoprevention in Ghanaian children: Protocol for a cluster randomised controlled trial. [PDF]
Trop Med Int HealthAbstract Objectives To evaluate the effectiveness and cost‐effectiveness of integrating seasonal malaria chemoprevention (SMC) with mass drug administration for helminth control among school‐aged children living in communities where the burden of malaria and helminths is high in Ghana, West Africa.
Afolabi MO +6 more
europepmc +2 more sources
In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. [PDF]
, 2004 To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 2003
Adjuik, M +16 more
core +3 more sources
Interactions between DNA purinic bases and amodiaquine: A theoretical approach
Orbital: The Electronic Journal of Chemistry, 2010 We study theoretically the amodiaquine-adenine and amodiaquine-guanine adducts formation using Density Functional Theory (B3LYP) and the 6-31G(d) basis set for the geometry optimizations and 6-31+G(d,p) for the analysis of the global indexes ...
Valdemar Lacerda Júnior +3 more
doaj +1 more source
Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids [PDF]
, 2020 This is the pre-peer reviewed version of the following article: Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids, which has been published in final form at https://doi.org/10.1002/slct.201903835.
Carda, Miguel +6 more
core +1 more source
Saleability of Anti-malarials in Private Drug Shops in Muheza, Tanzania: A Baseline study in an era of assumed Artemisinin Ccombination Therapy (ACT). [PDF]
, 2011 Artemether-lumefantrine (ALu) replaced sulphadoxine-pymimethamine (SP) as the official first-line anti-malarial in Tanzania in November 2006. So far, artemisinin combination therapy (ACT) is contra-indicated during pregnancy by the national malaria ...
AM Rønn +26 more
core +4 more sources
The Lancet, 1985 In eastern Thailand, 14 adults with moderately severe falciparum malaria were treated with intravenous amodiaquine dihydrochloride, loading dose 10 mg base/kg infused over 4 h followed by three further intravenous infusions of 5 mg base/kg at 24, 48, and 72 h.
Looareesuwan, S +6 more
openaire +4 more sources
Biomédica: revista del Instituto Nacional de Salud, 2003 La resistencia a los antimaláricos es una de las causas del aumento de casos de malaria en el mundo. Desde el año 2000, el tratamiento de malaria no complicada por Plasmodium falciparum en Colombia ha sido la combinación de amodiaquina (AQ) y sulfadoxina/
Iveth J. González +3 more
doaj +1 more source
Annals of Internal Medicine, 1986 Excerpt To the editor: Prophylaxis of malaria by amodiaquine is dangerous (1, 2). At least 20 cases of amodiaquine-associated agranulocytosis have been discovered so far in Switzerland, and 12 of t...
openaire +3 more sources
Amodiaquine and malaria prophylaxis
Parasitology Today, 1986 Abstract In 1985 the WHO and the United States Centers for Disease Control recommended that amodiaquine (400 mg weekly) could be used as a first-line malaria prophylactic in areas of the world with chloroquine resistance. Recently both the WHO and the CDC have withdrawn this recommendation.
Peto, T. E.A., Gilks, C. F.
openaire +3 more sources
Effects of immunization and checkpoint inhibition on amodiaquine-induced liver injury
Journal of Immunotoxicology, 2017 If idiosyncratic drug-induced liver injury (IDILI) is immune-mediated, it is possible that an individual’s prior exposure to antigens may affect their susceptibility to IDILI.
Alastair Mak +2 more
doaj +1 more source