Results 31 to 40 of about 11,264 (186)

Adenosine monophosphate degradation and inosinic acid accumulation in the shrimp Penaeus japonicus

International Aquatic Research, 2017
Shrimp muscle contains taste component compounds, such as glutamic acid and inosinic acid (IMP). When both are present, taste intensity increases by fourfold to eightfold compared to that when only glutamic acid is present. Inosinic acid is generated via
Hiroko Seki, Kaori Nakazato, Naoko Hamada-Sato   +2 more
doaj   +1 more source

Role of AMPD2 in impaired glucose tolerance induced by high fructose diet

Molecular Genetics and Metabolism Reports, 2017
A high intake of products containing fructose is known to mediate insulin resistance. In the liver, AMPD2, an isoform of AMPD, has important glucose metabolic homeostasis functions including maintenance of AMP-activated protein kinase (AMPK).
Athanasius Wrin Hudoyo, Tetsuaki Hirase, Andreas Tandelillin, Masahiko Honda, Manabu Shirai, Jidong Cheng, Hiroko Morisaki, Takayuki Morisaki   +7 more
doaj   +1 more source

Kinetic Analysis of the Thermal Inactivation Behavior of AMP Deaminase and IMPase in Each Muscle Type of Yellowtail Seriola quinqueradiata

Fishes
In this study, a kinetic analysis was conducted to clarify the thermal inactivation behavior of AMP deaminase and IMPase, enzymes involved in the generation and degradation of inosine 5′-monophosphate (IMP) in the dorsal ordinary muscle (OM) and dark ...
Ayumi Furuta, Renri Okura, Chinatsu Kobayashi, Shota Tanimoto   +3 more
doaj   +1 more source

Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP

Frontiers in Pharmacology, 2019
Germline mutations in cellular-energy associated genes have been shown to lead to various monogenic disorders. Notably, mitochondrial disorders often impact skeletal muscle, brain, liver, heart, and kidneys, which are the body’s top energy-consuming ...
Todd A. Johnson, H. A. Jinnah, Naoyuki Kamatani   +2 more
doaj   +1 more source

Dietary intake of fructose increases purine de novo synthesis: A crucial mechanism for hyperuricemia

Frontiers in Nutrition, 2022
BackgroundFructose consumption is a potential risk factor for hyperuricemia because uric acid (UA) is a byproduct of fructose metabolism caused by the rapid consumption of adenosine triphosphate and accumulation of adenosine monophosphate (AMP) and other
Pengfei Zhang, Pengfei Zhang, Huimin Sun, Xinyu Cheng, Yajing Li, Yanli Zhao, Wuxuan Mei, Xing Wei, Hairong Zhou, Yunbo Du, Changchun Zeng   +10 more
doaj   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

Adenine nucleotide content and activity of AMP catabolism enzymes in the kidney of rats fed on diets with different protein and sucrose content

Біологічні студії
Background. Excessive consumption of sucrose or protein deficiency in the diet can induce metabolic disorders in the kidney, whose functioning requires significant ATP energy expenditure.
Halyna Kopylchuk, Oksana Voloshchuk
doaj   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Engineering Strategies for Fungal Cell Disruption in Biotechnological Applications

Engineering in Life Sciences, Volume 25, Issue 12, December 2025.
ABSTRACT Fungal cell disruption plays a critical role in unlocking a wide range of high‐value intracellular products such as lipids, proteins, pigments, and bioactive compounds. However, lysing fungal cells is far more challenging than breaking bacterial or algal cells due to their robust and highly structured cell walls.
Bhagyeshri Ulhas Mantri, Maliheh Vahidinasab, Sonja Berensmeier   +2 more
wiley   +1 more source