Results 51 to 60 of about 11,264 (186)

Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics

Microbial Biotechnology, Volume 18, Issue 12, December 2025.
This study explores the metabolic potential of Lentilactobacillus hilgardii for malolactic fermentation in winemaking. Genomic and in silico analyses, combined with experimental validation, reveal its resilience at low temperatures and unique enzymatic traits. Comparative insights with Oenococcus oeni highlight L.
Giacomo Mantegazza, Nicola Mangieri, Elnaz Vojoudi Yazdi, Pasquale Russo, Diego Mora, Giorgio Gargari   +5 more
wiley   +1 more source

Inhibition of adenosine 3′:5′-monophosphate accumulation in white fat cells by short chain fatty acids, lactate, and β-hydroxybutyrate

Journal of Lipid Research, 1976
The large increase in cyclic AMP accumulation by rat white fat cells seen in the presence of lipolytic agents plus methylxanthines and adenosine deaminase was markedly inhibited by lactate. However, lipolysis was unaffected by lactate.
J N Fain, R E Shephard
doaj   +1 more source

RNA-seq analysis uncovers effects of ammonia on metabolism, oxidant-antioxidant equilibrium and apoptosis in the red swamp crayfish (Procambarus clarkii)

Aquaculture Reports, 2020
Ammonia, as one of the major environmental pollutants in aquaculture, can lead to negative impacts on health and production of farmed animals. However, the underlying molecular mechanism of ammonia in crayfish remains unclear.
Long Wang, Hui Wang, Wenjing Shi, Yi Zhang, Guoliang Chang, Nan Wu, Chaopeng Xue, Jiale Li   +7 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Product activation of human erythrocyte AMP deaminase

FEBS Letters, 1998
IMP was found to activate AMP deaminase in crude glucose‐depleted human erythrocyte lysates. Activation of the enzyme by IMP is due to prevention of the inhibitory effect of inorganic phosphate. At 1 mM AMP and 2–3 mM phosphate the addition of 2–5 mM IMP accelerates the AMP deamination two to three times.
Mosharov, E.V, Vitvitsky, V.M, Ataullakhanov, F.I   +2 more
openaire   +2 more sources

Target of rapamycin signaling in pea embryos is dependent on glutamine but detached from seed storage protein biosynthesis

New Phytologist, Volume 248, Issue 6, Page 2833-2849, December 2025.
Summary Target of rapamycin (TOR) kinase is the hub of a eukaryotic master signaling network that integrates nutritional and hormonal signals into cellular activities. Most studies on TOR in plants have focused on seedlings, where TOR is most responsive to light and sucrose.
Brendan M. O'Leary, Suvi Honkanen, Vinti Kumari, Christoph Rampitsch, Eiji Nambara, A. Harvey Millar   +5 more
wiley   +1 more source

The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia

Asian Pacific Journal of Tropical Biomedicine, 2015
Objective: To verify possible associations between adenosine aminohydrolase (ADA) and AMP-aminohydrolase (AMPDA) to E3 SUMO-protein ligase NSE2 (NSMCE2) in patients with renal stones.
Faridah Yusof, Atheer Awad Mehde, Wesen Adel Mehdi, Hamid Ghazali, Azlina Abd Rahman   +4 more
doaj   +1 more source

JA Regulates Caffeine Biosynthesis in Tea Leaf for Resistance Against Fungal Infection and Antagonises With GA to Balance the Defence–Growth Trade‐Off via CsDELLA‐JAZ‐MYC2‐MYB184‐TCS1 Module

Plant Biotechnology Journal, Volume 23, Issue 12, Page 5865-5890, December 2025.
ABSTRACT Caffeine is a defensive alkaloid primarily accumulated in tea leaves to defend against pathogens. But the regulatory mechanism for caffeine biosynthesis in response to fungal infection and the trade‐off between specialised metabolite and plant growth remain elusive.
Zhili Ye, Ziqing Zheng, Jinsong Wang, Qinyu Zhong, Xiaoyu Mu, Zhoufang Yuan, Yin Huang, Zainab Ghazala, Hao Zuo, Yaling Li, Xiaoyu Liang, Yujia Qi, Xiongyuan Si, Yanrui Zhang, Enhua Xia, Jian Zhao, Penghui Li   +16 more
wiley   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You   +3 more
wiley   +1 more source

Hepatic ENTPD5 Is Critical for Maintaining Metabolic Homeostasis and Promoting Brown Adipose Tissue Thermogenesis

Advanced Science, Volume 12, Issue 40, October 27, 2025.
ENTPD5‐mediated conversion of extracellular adenosine triphosphate to ADP of hepatocytes is critical for maintaining hepatic glucose/lipid metabolism and promoting brown adipose tissue thermogenesis via the inhibition of adrenomedullin expression and secretion.
Rufeng Ma, Song Hou, Rui Xiang, Wenjun Liu, Xin Li, Yujing Chi, Ming Xu, Haochen Yao, Jing Li, Jichun Yang   +9 more
wiley   +1 more source