Results 61 to 70 of about 11,264 (186)

Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy

Advanced Science, Volume 12, Issue 40, October 27, 2025.
Metabolic rewiring in cancer is mapped across glucose, amino acid, lipid, nucleotide, and mitochondrial pathways, with emphasis on immune regulation. The review integrates mechanisms linking these pathways to tumor progression and therapy resistance, and profiles nanomaterial platforms that both deliver therapeutics and actively reprogram ...
Xiaosu Zhou, Ruibing Deng, Zunde Liao, Xiaoyu Huang, Junting Huang, Hanlou Yang, Kam W. Leong, Yiling Zhong   +7 more
wiley   +1 more source

Current status and future perspectives of multi‐modal bacteria‐based cancer therapies

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Bacteria exhibit inherent tumour‐targeting capabilities, particularly thriving in hypoxic tumour microenvironments (TMEs) and activating potent anti‐tumour immune responses through pathogen‐associated molecular patterns (PAMPs) and immunomodulation.
Shuai Fan, Siyu Zhu, Wenyu Wang, Yuetong Liu, Yutong Zhou, Hao Li, Bofeng Liu, Qin Xia, Lili Huang, Lei Dong   +9 more
wiley   +1 more source

Control of ATP homeostasis during the respiro‐fermentative transition in yeast

Molecular Systems Biology, 2010
Respiring Saccharomyces cerevisiae cells respond to a sudden increase in glucose concentration by a pronounced drop of their adenine nucleotide content ([ATP]+[ADP]+[AMP]=[AXP]).
Thomas Walther, Maite Novo, Katrin Rössger, Fabien Létisse, Marie‐Odile Loret, Jean‐Charles Portais, Jean‐Marie François   +6 more
doaj   +1 more source

Purinergic Signaling in Pulmonary Inflammation

Frontiers in Immunology, 2019
Purine nucleotides and nucleosides are at the center of biologic reactions. In particular, adenosine triphosphate (ATP) is the fundamental energy currency of cellular activity and adenosine has been demonstrated to play essential roles in human ...
Thanh-Thuy T. Le, Nathaniel K. Berg, Matthew T. Harting, Xiangyun Li, Xiangyun Li, Holger K. Eltzschig, Xiaoyi Yuan   +6 more
doaj   +1 more source

Yeast to Study Human Purine Metabolism Diseases

Cells, 2019
Purine nucleotides are involved in a multitude of cellular processes, and the dysfunction of purine metabolism has drastic physiological and pathological consequences.
Bertrand Daignan-Fornier, Benoît Pinson
doaj   +1 more source

Gemcitabine-loaded liposomes: rationale, potentialities and future perspectives

International Journal of Nanomedicine, 2012
Cinzia Federico, Valeria M Morittu, Domenico Britti, Elena Trapasso, Donato CoscoDepartment of Health Sciences, Building of BioSciences, University “Magna Græcia” of Catanzaro, Campus Universitario “S Venuta& ...
Federico C, Morittu VM, Britti D, Trapasso E, Cosco D   +4 more
doaj  

The AMP deaminase of the mollusk Helix pomatia is an unexpected member of the adenosine deaminase-related growth factor (ADGF) family. [PDF]

PLoS One, 2023
Tzertzinis G, Ganatra MB, Ruse C, Taron CH, Causey B, Wang L, Schildkraut I.   +6 more
europepmc   +1 more source

Modulation of mammalian cardiac AMP deaminase by protein kinase C-mediated phosphorylation [PDF]

, 1993
Jay K. Thakkar, David R. Janero, C Yarwood, H. Sharif   +3 more
openalex   +1 more source

Enhancer regulator MLL4 controls skeletal muscle metabolic efficiency by limiting AMPK-mediated fuel catabolism

Nature Communications
Skeletal muscle is a major organ for maintaining whole-body energy balance, yet how it adapts its transcriptional and metabolic programs to environmental cues remains unclear.
Likun Yang, Lin Liu, Wen Wang, Chenyun Ding, Aneesh K. Asokan, Tingze Feng, Danxia Zhou, Zhisheng Xu, Tingting Fu, Qiqi Guo, Zheng Zhou, Shaojun Pei, Gonghao Shen, Liwei Xiao, Yujing Yin, Zongchao Sun, Yan Mao, Wanping Sun, Jinjie Li, Jiacheng Xue, Min-Sheng Zhu, Kai Ge, K. Sreekumaran Nair, Hai-Long Piao, Zhenji Gan   +24 more
doaj   +1 more source

Fructose: A Key Factor in the Development of Metabolic Syndrome and Hypertension

Journal of Nutrition and Metabolism, 2013
Diabetes mellitus and the metabolic syndrome are becoming leading causes of death in the world. Identifying the etiology of diabetes is key to prevention. Despite the similarity in their structures, fructose and glucose are metabolized in different ways.
Zeid Khitan, Dong Hyun Kim
doaj   +1 more source