Results 261 to 270 of about 2,373,510 (375)

Whole‐Genome Resequencing Provides Novel Insights Into the Genetic Diversity, Population Structure, and Patterns of Runs of Homozygosity in Mud Crab (Scylla paramamosain)

open access: yesEvolutionary Applications, Volume 18, Issue 9, September 2025.
ABSTRACT Mud crab (Scylla paramamosain) is an economically important aquaculture crustacean species in China and Southeast Asia countries. However, the catches of wild mud crabs declined sharply due to overfishing and environmental pollution. Therefore, it is necessary to understand the current genetic resources and population history of mud crab (S ...
Xiyi Zhou   +5 more
wiley   +1 more source

Decoding Pain: Next‐Generation In Vitro Systems for Mechanistic Insights and Drug Discovery

open access: yesThe FASEB Journal, Volume 39, Issue 16, 31 August 2025.
Developing an in vitro pain model that mimics essential features of the in vivo pain circuit requires careful consideration of multiple components and choices. These include selecting the cellular population for the model, choosing from the origin of nociceptors and other cells that are cultured, deciding between 3D or 2D dimensions, designing the ...
Dara Khosrowshahi   +2 more
wiley   +1 more source

Ketamine Reverses Chronic Stress‐Induced Behavioral Changes via the Expression of Ca2+‐Permeable AMPA Receptors in Mice

open access: yesThe FASEB Journal, Volume 39, Issue 16, 31 August 2025.
Low‐dose ketamine rapidly induces the expression of GluA1‐containing, GluA2‐lacking Ca2+‐Permeable AMPARs (CP‐AMPARs) in the hippocampus via NMDAR antagonism. When ketamine is administered, CP‐AMPAR‐mediated Ca2+ influx may replace NMDAR‐dependent Ca2+ signaling. This increases neural plasticity, which leads to antistress effects in animals. Therefore,
Joshua C. Flowers   +9 more
wiley   +1 more source

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