Results 241 to 250 of about 53,245 (286)
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Functional modulation of AMPA receptors by transmembrane AMPA receptor regulatory proteins
Neuroscience, 2009The AMPA receptors are ligand-gated ion channels belonging to the family of ionotropic glutamate receptors. They play an essential role in fast excitatory synaptic transmission in the CNS of vertebrates. Their activity-dependent directed transport and fast turnover at the plasma membrane contribute to synaptic plasticity and require numerous ...
C, Sager +3 more
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Expert Opinion on Therapeutic Patents, 1999
It is now generally recognised that glutamate is the major excitatory neurotransmitter in vertebrate central nervous system (CNS). It acts at ionotropic and metabotropic receptors which appear to play important roles in all aspects of CNS functions. The ionotropic receptors, which are involved in fast synaptic transmission, belong to three subtypes ...
CHIMIRRI, Alba +2 more
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It is now generally recognised that glutamate is the major excitatory neurotransmitter in vertebrate central nervous system (CNS). It acts at ionotropic and metabotropic receptors which appear to play important roles in all aspects of CNS functions. The ionotropic receptors, which are involved in fast synaptic transmission, belong to three subtypes ...
CHIMIRRI, Alba +2 more
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Current Pharmaceutical Design, 1996
AMPA and kainate receptors belong to a common family of ionotropic glutamate receptors. Molecular biology has revealed some of the molecular features that are responsible for selective ion permeability of the receptor comp.lex. The diversity of subunits and their combination into hetero-oligomeric recep or complexes have provided evidence that ...
Christopher F. Bigge +2 more
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AMPA and kainate receptors belong to a common family of ionotropic glutamate receptors. Molecular biology has revealed some of the molecular features that are responsible for selective ion permeability of the receptor comp.lex. The diversity of subunits and their combination into hetero-oligomeric recep or complexes have provided evidence that ...
Christopher F. Bigge +2 more
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Science, 2009
A distinctive family of proteins involved in the assembly of the most common excitatory brain receptor has been discovered.
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A distinctive family of proteins involved in the assembly of the most common excitatory brain receptor has been discovered.
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Neurology, 2016
In this and forthcoming reviews, a representative clinical case will serve as an introduction to the topic to be discussed. This will provide the basis to address some recent insights from basic neuroscience research on the normal function of the primary target of the disease process involved in the case presented, as well as putative pathophysiologic ...
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In this and forthcoming reviews, a representative clinical case will serve as an introduction to the topic to be discussed. This will provide the basis to address some recent insights from basic neuroscience research on the normal function of the primary target of the disease process involved in the case presented, as well as putative pathophysiologic ...
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Stargazin modulates AMPA receptor antagonism
Neuropharmacology, 2008AMPA receptors mediate the majority of fast synaptic transmission and underlie several forms of synaptic plasticity. AMPARs also have an important role in several neuronal pathologies. Therefore, studying the structure and function of these receptors is important for understanding general mechanisms of synaptic transmission as well as for the ...
Cokic, B., Stein, V.
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Science, 2010
A protein expressed in brain controls the plasticity of synaptic transmission by regulating the properties of a neurotransmitter receptor.
Mark Farrant, Stuart G. Cull-Candy
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A protein expressed in brain controls the plasticity of synaptic transmission by regulating the properties of a neurotransmitter receptor.
Mark Farrant, Stuart G. Cull-Candy
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AMPA Receptor Trafficking and GluR1
Science, 2005In their Research Article “Postsynaptic receptor trafficking underlying a form of associative learning” (1 Apr., p. 83), S. Rumpel et al. draw the important conclusions that “encoding of memories in the lateral amygdala is mediated by AMPA receptor trafficking” and that “synaptic incorporation of AMPARs is necessary for learning.” The key experiment ...
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Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition
Nature, 2021Prashant Rao, Jaba Mitra
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