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Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction.

Science, 2000
To elucidate mechanisms that control and execute activity-dependent synaptic plasticity, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors (AMPA-Rs) with an electrophysiological tag were expressed in rat hippocampal neurons.
Y. Hayashi   +5 more
semanticscholar   +1 more source

AMPA Receptor Antagonists

Current Medicinal Chemistry, 2001
AMPA Receptor antagonists have received considerable attention in recent years. Within the class of excitatory amino acid receptor antagonists AMPA receptor antagonists have shown excellent neuroprotection in several models of cerebral ischemia and neuronal injury.
Sham Shridhar Nikam   +1 more
openaire   +2 more sources

AMPA receptor antagonists

Expert Opinion on Therapeutic Patents, 1999
It is now generally recognised that glutamate is the major excitatory neurotransmitter in vertebrate central nervous system (CNS). It acts at ionotropic and metabotropic receptors which appear to play important roles in all aspects of CNS functions. The ionotropic receptors, which are involved in fast synaptic transmission, belong to three subtypes ...
CHIMIRRI, Alba   +2 more
openaire   +3 more sources

Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation.

Science, 1999
To monitor changes in alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor distribution in living neurons, the AMPA receptor subunit GluR1 was tagged with green fluorescent protein (GFP).
Song-Hai Shi   +6 more
semanticscholar   +1 more source

Competitive AMPA Receptor Antagonists

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
CATARZI, DANIELA   +2 more
openaire   +4 more sources

AMPA receptors

Neurology, 2016
In this and forthcoming reviews, a representative clinical case will serve as an introduction to the topic to be discussed. This will provide the basis to address some recent insights from basic neuroscience research on the normal function of the primary target of the disease process involved in the case presented, as well as putative pathophysiologic ...
E. Benarroch
semanticscholar   +4 more sources

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