Results 1 to 10 of about 123,256 (238)

Amphetamine and pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats [PDF]

BMC Neuroscience, 2008
Background Pseudoephedrine is a drug commonly prescribed as a nasal decongestant and bronchodilator and is also freely available in cold remedies and medications.
Casalotti Stefano O, Tongjaroenbuangam Walaiporn, Ruksee Nootchanart, Govitrapong Piyarat   +3 more
doaj   +5 more sources

D-amphetamine alters the dynamic ECoG activity distribution patterns in the rat neocortex [PDF]

Scientific Reports
Amphetamine has widespread effects on multiple neurotransmitter systems, potentially altering the physiological connectivity and network dynamics across various regions of the brain.
Astrid Mellbin, Henrik Jörntell, Fredrik Bengtsson   +2 more
doaj   +2 more sources

Analysis of fatalities involving amphetamine in Jazan, Saudi Arabia

Forensic Science International: Reports, 2021
Amphetamine use is associated with high tendence of homicidal or suicidal deaths and fatalities making amphetamine a persistent area of concern. This study analyzed fatalities associated with amphetamine use in Jazan city, Saudi Aarabia from 2018 to 2020
Ibraheem M. Attafi, Murad M. Tumayhi, David Banji, Mohammed Y. Albeishy, Ibrahim A. Khardali, Hesham M. Korashy   +5 more
doaj   +1 more source

Amphetamine-Decreased Progesterone and Estradiol Release in Rat Granulosa Cells: The Regulatory Role of cAMP- and Ca²⁺-Mediated Signaling Pathways

Biomedicines, 2021
The purpose of this study is to evaluate the amphetamine effects on progesterone and estradiol production in rat granulosa cells and the underlying cellular regulatory mechanisms.
Chung-Yu Chen, Chien-Rung Chen, Chiao-Nan Chen, Paulus S. Wang, Toby Mündel, Yi-Hung Liao, Shiow-Chwen Tsai   +6 more
doaj   +1 more source

Enantioselective Quantification of Amphetamine and Metabolites in Serum Samples: Forensic Evaluation and Estimation of Consumption Time

Metabolites, 2021
In forensic toxicology, amphetamine intoxications represent one of the most common case groups and present difficult questions for toxicologists. Estimating the time of consumption and the current influence of the stimulant is particularly difficult when
Moritz Losacker, Michael Kraemer, Alexandra Philipsen, Kristina Duecker, Nadine Dreimueller, Jan Engelmann, Joerg Roehrich, Cornelius Hess   +7 more
doaj   +1 more source

Effects of Lisdexamfetamine, a Prodrug of D-Amphetamine, on Locomotion, Spatial Cognitive Processing and Neurochemical Profiles in Rats: A Comparison With Immediate-Release Amphetamine

Frontiers in Psychiatry, 2022
D-amphetamine has been used to enhance cognitive performance over the last few decades. Due to the rapid absorption after administration, d-amphetamine shows narrow effective window and severe abuse potential. Lisdexamfetamine, a prodrug of d-amphetamine,
Chen Jian-min, Wang Zhi-yuan, Wu Shi-xuan, Song Rui, Wu Ning, Li Jin   +5 more
doaj   +1 more source

Elevated body fat increases amphetamine accumulation in brain: evidence from genetic and diet-induced forms of adiposity

Translational Psychiatry, 2021
Despite the high prevalence of obesity, little is known about its potential impact on the pharmacokinetics of psychotropic drugs. In the course of investigating the role of the microRNA system on neuronal signaling, we found that mice lacking the ...
Xiuping Fu, Aparna P. Shah, Jacqueline Keighron, Ta-Chung M. Mou, Bruce Ladenheim, Jesse Alt, Daisuke Fukudome, Minae Niwa, Kellie L. Tamashiro, Gianluigi Tanda, Akira Sawa, Jean-Lud Cadet, Rana Rais, Jay M. Baraban   +13 more
doaj   +1 more source

D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats

Frontiers in Pharmacology, 2021
D-amphetamine induces emergence from sevoflurane and propofol anesthesia in rats. Dexmedetomidine is an α2-adrenoreceptor agonist that is commonly used for procedural sedation, whereas ketamine is an anesthetic that acts primarily by inhibiting NMDA-type
Risako Kato, Risako Kato, Edlyn R. Zhang, Olivia G. Mallari, Olivia A. Moody, Olivia A. Moody, Kathleen F. Vincent, Kathleen F. Vincent, Eric D. Melonakos, Eric D. Melonakos, Morgan J. Siegmann, Christa J. Nehs, Christa J. Nehs, Timothy T. Houle, Timothy T. Houle, Oluwaseun Akeju, Oluwaseun Akeju, Ken Solt, Ken Solt   +18 more
doaj   +1 more source

Negative Impact of Amphetamine-Type Stimulant Use on Opioid Agonist Treatment Retention in Ontario, Canada

Frontiers in Psychiatry, 2021
Objective: The objective of this study was to evaluate epidemiological trends of co-use patterns of amphetamine-type stimulants and opioids and the impact of co-use patterns on Opioid Agonist Treatment (OAT) retention in Ontario, Canada.
Kristen A. Morin, Kristen A. Morin, Kristen A. Morin, Frank Vojtesek, Shreedhar Acharya, David C. Marsh, David C. Marsh, David C. Marsh, David C. Marsh   +8 more
doaj   +1 more source

Does illicit amphetamine seizures quantity associated with amphetamine use disorder related admissions in Saudi Arabia?

BMC Psychiatry, 2023
Background Illicit amphetamine-type stimulants (ATS) trafficking activities have increased substantially in Saudi Arabia over the last 10 years. In the period 2013–2017 Saudi Arabia seized the largest quantities of amphetamine at the global level.
Majed Ramadan, Enas Ghulam, Noara Alhusseini   +2 more
doaj   +1 more source