Results 31 to 40 of about 276 (135)
Synthesis of the C(43)−C(67) Fragment of Amphidinol 3
, 2016 A synthesis of the C(43)−C(67) fragment of amphidinol 3 (AM3) has been accomplished by a route that features the use of a double allylboration reaction for synthesis of 1,5-diol 4b, which serves as a precursor to dihydropyran ...
Jacqueline D. Hicks (2335909) +2 more
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Structure of Membrane-Bound Amphidinol 3 in Isotropic Small Bicelles
, 2016 Amphidinol 3 (AM3) exhibits a potent membrane permeabilizing activity by forming pores in biological membranes. We examined the conformation and location of AM3 using isotropic bicelles, a more natural membrane model than micelles.
Nobuaki Matsumori (1450381) +2 more
core +1 more source
, 2016 An efficient synthesis of the C1−C14 fragment of amphidinol 3 is described.
Samir BouzBouz (2476753) +1 more
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The Synthesis of Natural Product Amphidinol 7 Models
, 2008 The amphidinols (AMs) are a series of polyhydroxylated polyene compounds isolated from the dinoflagellate genus Amphidinium. The first serial amphidinol 1 (AMl) was isolated and characterized by 13C NMR and 2D NMRin 1991.
Liu, Lin
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Synthesis and Structure Revision of the C43–C67 Part of Amphidinol 3
, 2016 Stereoselective synthesis of the C43–C67 part of amphidinol 3 (AM3) and its C51-epimer was achieved starting from a common intermediate corresponding to the tetrahydropyran moiety of AM3, via asymmetric oxidations and Julia–Kocienski olefination.
Yoshiyuki Manabe (1951255) +7 more
core +1 more source
Towards the synthesis of C43 to C51 unit of Amphidinol-3 [PDF]
, 2020 369-375Towards the synthesis of C43 to C51 unit of Amphidinol-3 has been achieved following our recently developed protocol for the highly stereoselective synthesis of trans-2,6-disubstituted dihydropyran through tandem isomerization followed by C–O and ...
Yadav, Jhillu Singh, Bhaskar, K
core
, 2016 Combinatorial synthesis of a 1,5-polyol system corresponding to the C1−C14 unit of amphidinol 3 (AM3) and its diastereomers was achieved via chemoselective cross metathesis as the key step.
Nobuaki Matsumori (1450381) +4 more
core +2 more sources
Confirmation of the Absolute Configuration at C45 of Amphidinol 3
, 2016 Amphidinol 3 (AM3), a membrane-active agent isolated from the dinoflagellate Amphidinium klebsii, consists of a long carbon chain containing 25 stereogenic centers.
Yoshiyuki Manabe (1951255) +4 more
core +1 more source
, 2008 Model compounds (11 and 12) for the C1–C10 tetrahydropyran fragment of amphidinol 2 were prepared from (2S)-benzyloxypropanal in 9 steps. The synthetic route relied on diastereoselective diene-aldehyde cycloaddition, stereoselective C-allylation, and ...
Kommana, Praveen +2 more
core
Stereoselective Synthesis of the C1–C29 Part of Amphidinol 3
, 2016 Stereoselective synthesis of the C1–C29 part of amphidinol 3 (AM3) was achieved. The C1–C20 part was assembled from three building blocks via regioselective cross metathesis to form the C4–C5 double bond and addition of an alkenyllithium and a lithium ...
Tohru Oishi (1581409) +3 more
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