Results 1 to 10 of about 88,713 (223)
MAMC Journal of Medical Sciences, 2021 Amphotericin B, one of the first systemic antifungal agents, has been in use since the past six decades. In light of the recent outbreak of mucormycosis (black fungus) cases during the second coronavirus disease 2019 wave in India, the relevance of ...
Sahil Kumar, Vandana Roy
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Amphotericin B induced pancytopenia
Journal of Family Medicine and Primary Care, 2022 Amphotericin B (AMB) has been the irreplaceable drug of choice for countless fungal and protozoal infections. One of the lesser-known adverse effects of AMB is Pancytopenia - very rare with very few cases reported - most commonly observed following ...
Esha Vaish +3 more
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Encochleated Amphotericin B: Is the Oral Availability of Amphotericin B Finally Reached?
Journal of Fungi, 2020 As the oldest and for many decades the only available agent for the treatment of life-threatening invasive fungal diseases, amphotericin B (AmB) is known for its broad-spectrum fungicidal activity against a wide range of yeasts and molds.
Maria Aigner, Cornelia Lass-Flörl
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An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety. [PDF]
PLoS ONE, 2016 Amphotericin B is the most potent antimycotic known to date. However due to its large collateral toxicity, its use, although long standing, had been limited. Many attempts have been made to produce derivatives with reduced collateral damage.
Armando Antillón +21 more
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Frontiers in Genetics, 2023 Aspergillus fumigatus is one of the most common pathogenic fungi, which results in high morbidity and mortality in immunocompromised patients. Amphotericin B (AMB) is used as the core drug for the treatment of triazole-resistant A. fumigatus.
Meng-Meng Chen +7 more
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Inhibition of nucleotide biosynthesis potentiates the antifungal activity of amphotericin B. [PDF]
PLoS ONE, 2014 The polyene antifungal agent Amphotericin B exhibits potent and broad spectrum fungicidal activity. However, high nephrotoxicity can hinder its administration in resource poor settings.
Dithi Banerjee +2 more
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Journal of Global Antimicrobial Resistance, 2020 Objective: G-ABCD is a biosimilar product of amphotericin B colloidal dispersion (ABCD). This study was designed to systematically examine the plasma pharmacokinetics (PK) and tissue distribution of G-ABCD in rats, using amphotericin B deoxycholate (DAmB)
Huanhuan Qi +6 more
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Lipase-Responsive Amphotericin B Loaded PCL Nanoparticles for Antifungal Therapies
Nanomaterials, 2022 Amphotericin B is an antifungal drug used for the treatment of invasive fungal infections. However, its clinical use is limited due to its serious side effects, such as renal and cardiovascular toxicity.
Evelyn Osehontue Uroro +3 more
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Antibiotics, 2022 Fungal infections represent a serious complication during the post-liver transplantation period. Abdominal infections can occur following pre-existing colonization, surgical procedures, and permanence of abdominal tubes.
Francesca Tortora +9 more
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