Results 1 to 10 of about 374,595 (258)
Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B [PDF]
Journal of Orthopaedic Surgery and ResearchBackground Amphotericin is admixed to Polymethylmethacrylic (PMMA) spacers for fungal periprosthetic joint infections (PJI) during two-stage exchanges. We aimed to analyse the mechanical properties of PMMA cement with admixed Amphotericin B.
Florian A. Frank +6 more
doaj +2 more sources
Real-World Effectiveness and Safety of Isavuconazole Versus Amphotericin B for Patients with Invasive Mucormycosis [PDF]
MicroorganismsBackground: Invasive mucormycosis (IM) poses a substantial morbidity and mortality burden among immunocompromised patients. Objectives: We aim to compare the real-world effectiveness and safety of isavuconazole with those of amphotericin B in patients ...
Jiayuan Qin +6 more
doaj +2 more sources
Patterns of Amphotericin B Use and Factors Related to Mortality in a Low-Middle Income Country: An Observational and Longitudinal Study [PDF]
AntibioticsBackground/Objectives: Amphotericin B is indicated in deep systemic fungal infections. The aim was to determine the sociodemographic, clinical and pharmacological variables of a group of Colombian patients treated with amphotericin B and factors ...
Luis Fernando Valladales-Restrepo +6 more
doaj +2 more sources
MAMC Journal of Medical Sciences, 2021 Amphotericin B, one of the first systemic antifungal agents, has been in use since the past six decades. In light of the recent outbreak of mucormycosis (black fungus) cases during the second coronavirus disease 2019 wave in India, the relevance of ...
Sahil Kumar, Vandana Roy
doaj +1 more source
Amphotericin B induced pancytopenia
Journal of Family Medicine and Primary Care, 2022 Amphotericin B (AMB) has been the irreplaceable drug of choice for countless fungal and protozoal infections. One of the lesser-known adverse effects of AMB is Pancytopenia - very rare with very few cases reported - most commonly observed following ...
Esha Vaish +3 more
doaj +1 more source
Encochleated Amphotericin B: Is the Oral Availability of Amphotericin B Finally Reached?
Journal of Fungi, 2020 As the oldest and for many decades the only available agent for the treatment of life-threatening invasive fungal diseases, amphotericin B (AmB) is known for its broad-spectrum fungicidal activity against a wide range of yeasts and molds.
Maria Aigner, Cornelia Lass-Flörl
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An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety. [PDF]
PLoS ONE, 2016 Amphotericin B is the most potent antimycotic known to date. However due to its large collateral toxicity, its use, although long standing, had been limited. Many attempts have been made to produce derivatives with reduced collateral damage.
Armando Antillón +21 more
doaj +1 more source
Frontiers in Genetics, 2023 Aspergillus fumigatus is one of the most common pathogenic fungi, which results in high morbidity and mortality in immunocompromised patients. Amphotericin B (AMB) is used as the core drug for the treatment of triazole-resistant A. fumigatus.
Meng-Meng Chen +7 more
doaj +1 more source
Inhibition of nucleotide biosynthesis potentiates the antifungal activity of amphotericin B. [PDF]
PLoS ONE, 2014 The polyene antifungal agent Amphotericin B exhibits potent and broad spectrum fungicidal activity. However, high nephrotoxicity can hinder its administration in resource poor settings.
Dithi Banerjee +2 more
doaj +1 more source
Antibiotics, 2022 Fungal infections represent a serious complication during the post-liver transplantation period. Abdominal infections can occur following pre-existing colonization, surgical procedures, and permanence of abdominal tubes.
Francesca Tortora +9 more
doaj +1 more source