Results 91 to 100 of about 13,097,347 (378)

Polymorphic α‐Glucans as Structural Scaffolds in Cryptococcus Cell Walls for Chitin, Capsule, and Melanin: Insights From 13C and 1H Solid‐State NMR

Angewandte Chemie, EarlyView.
Cryptococcus neoformans cell wall α‐1,3‐glucans as dual anchors for melanin and capsule: Solid‐state NMR of intact C. neoformans cells reveals five forms of α‐1,3‐glucans that structurally bridge melanin and capsule layers. These polysaccharides interact with chitin, chitosan, and β‐glucans to create a molecular scaffold that underlies virulence and ...
Ankur Ankur, Jayasubba Reddy Yarava, Isha Gautam, Faith J. Scott, Frederic Mentink‐Vigier, Christine Chrissian, Li Xie, Dibakar Roy, Ruth E. Stark, Tamara L. Doering, Ping Wang, Tuo Wang   +11 more
wiley   +2 more sources

Growth Factor‐Loaded Mesoporous Silica Particles, Incorporated in Electrospun PCL Fibres, Provide Topographical and Chemical Cues for Tendon Tissue Engineering

Advanced Materials Technologies, EarlyView.
Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro, Marta Clerici, Matthew T. Shephard, Tina P. Dale, Aldo R. Boccaccini, Nicholas R. Forsyth   +5 more
wiley   +1 more source

First report of amphotericin B resistant Candida haemulonii isolated from the ICU of a referral hospital in Indonesia

Iranian Journal of Microbiology
Background and Objectives: Amphotericin B is a broad-spectrum antifungal agent commonly used to treat Candida haemulonii infection. C. haemulonii was isolated from patients reported to be intrinsically resistant to amphotericin B, encoded by the ERG2 ...
Rifdah Hanifah, Mardiastuti Wahid, Andi Yasmon   +2 more
doaj   +1 more source

Amphotericin B deoxycholate for relapse visceral leishmaniasis in Bangladesh: a cross-sectional study

BMC Research Notes, 2018
Objective Based on studies in India (as there was no studies from outside India) amphotericin B deoxycholate has been considered as a backup drug for treatment of visceral leishmaniasis.
Md Golam Hasnain, Proggananda Nath, Shomik Maruf, Shah Golam Nabi, A. F. M. Akhtar Hossain, Be-Nazir Ahmed, Dinesh Mondal, Ariful Basher   +7 more
doaj   +1 more source

In vitro activities of amphotericin B, terbinafine, and azole drugs against clinical and environmental isolates of apergillus terreus Sensu Stricto [PDF]

, 2015
The antifungal susceptibilities of 40 clinical and environmental isolates of A. terreus sensu stricto to amphotericin B, terbinafine, itraconazole, and voriconazole were determined in accordance with CLSI document M38-A2.
Cattana, Maria Emilia, Fernández, Mariana Soledad, Giusiano, Gustavo Emilio, Iovannitti, Cristina A., Lass Flörl, Cornelia, Rojas, Florencia Dinorah, Sosa, Maria de Los Angeles   +6 more
core   +1 more source

Efficacy and Safety of Liposomal Amphotericin B for the Treatment of Mucosal Leishmaniasis from the New World: A Retrospective Study.

American Journal of Tropical Medicine and Hygiene, 2015
The standard treatment of mucosal leishmaniasis (ML) is pentavalent antimonials, agents with serious adverse effects. Alternative agents include amphotericin B deoxycholate and liposomal amphotericin B.
M. Cunha, A. C. Leão, Rita de Cássia Soler, J. Lindoso   +3 more
semanticscholar   +1 more source

Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity

Advanced Science, EarlyView.
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi, Claudia Corbo, Julia Enterria‐Rosales, John Otto Martinez, Silvia Minardi, Laura Pandolfi, Xing Wang, Ennio Tasciotti, Kavindra V. Singh, Cesar A. Arias, Bruna Corradetti   +10 more
wiley   +1 more source

In vitro activities of antifungals alone and in combination with tigecycline against Candida albicans biofilms [PDF]

PeerJ, 2018
Background Candida may form biofilms, which are thought to underlie the most recalcitrant infections. Methods In this study, activities of antifungal agents alone and in combination with tigecycline against planktonic cells and mature and developing ...
Mayram Hacioglu, Ayse Seher Birteksoz Tan, Sibel Dosler, Nese Inan, Gulten Otuk   +4 more
doaj   +2 more sources

Anfotericina B forma liposómica: un perfil farmacocinético exclusivo. Una historia inacabada. [PDF]

, 2012
Amphotericin B in its lipid formulation continues to be the reference drug in the treatment of systemic fungal infections despite the time elapse since the development of this compound.
Azanza, J.R. (José Ramón), Barberan, J. (Jose)   +1 more
core  

Resolving Artifacts in Voltage‐Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings

Advanced Science, EarlyView.
Patch‐clamp experiments are fundamental to the measurement and understanding of ion currents that underlie physiological functions from neural activity to muscle contraction. Via a mathematical model of the experimental apparatus, this article highlights how artifact effects can be as large as some reported mutation and drug effects, and enables ...
Chon Lok Lei, Alexander P. Clark, Michael Clerx, Siyu Wei, Meye Bloothooft, Teun P. de Boer, David J. Christini, Trine Krogh‐Madsen, Gary R. Mirams   +8 more
wiley   +1 more source