Results 41 to 50 of about 13,097,347 (378)
Amphotericin B-Induced Encephalopathy
Pediatric Neurology Briefs, 1995 Three children with refractory leukemia treated by bone marrow transplantation at the Children’s National Medical Center, Washington, DC, developed encephalopathy, leukoencephalopathy, and parkinsonism after receiving high-dose amphotericin B for ...
J Gordon Millichap
doaj +1 more source
Pharmaceutics, 2019 Parenteral amphotericin B has been considered as first-line therapy in the treatment of systemic fungal and parasitic infections, however its use has been associated with a number of limitations including affordability, accessibility, and an array of ...
Grace Cuddihy +3 more
semanticscholar +1 more source
In vitro antifungal activities of amphotericin B and liposome-encapsulated amphotericin B [PDF]
Antimicrobial Agents and Chemotherapy, 1984 The in vitro activities of liposome-encapsulated amphotericin B and free amphotericin B against Candida albicans 336 were comparable. Amphotericin B concentrations 12-fold and greater than 50-fold higher were required to kill the same organism when cholesterol and ergosterol were incorporated into the liposomes. The addition of cholesterol to liposomes
K. Mills +5 more
openaire +3 more sources
Eradication of Candida albicans persister cell biofilm by the membranotropic peptide gH625 [PDF]
, 2020 Biofilm formation poses an important clinical trouble due to resistance to antimicrobial agents; therefore, there is an urgent demand for new antibiofilm strategies that focus on the use of alternative compounds also in combination with conventional ...
D'Alterio, A. +8 more
core +1 more source
Efficacy of Oral Encochleated Amphotericin B in a Mouse Model of Cryptococcal Meningoencephalitis
mBio, 2019 Cryptococcus neoformans is a significant global fungal pathogen that kills an estimated quarter of a million HIV-infected individuals yearly and has poor outcomes despite therapy. The most effective therapy, amphotericin B, is highly effective in killing
R. Lu +13 more
semanticscholar +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2022 Objective: To characterize the antifungal activity of methanolic leaf extract of Calotropis gigantea alone or in combination with amphotericin B against invasive pulmonary aspergillosis in mice. Methods: GC/MS was used for analysis of active constituents
Enas M Ali +2 more
doaj +1 more source
Voriconazole Compared with Liposomal Amphotericin B for Empirical Antifungal Therapy in Patients with Neutropenia and Persistent Fever [PDF]
, 2002 Background Patients with neutropenia and persistent fever are often treated empirically with amphotericin B or liposomal amphotericin B to prevent invasive fungal infections.
Donowitz, Gerald +10 more
core +2 more sources
Designing Fast-Dissolving Orodispersible Films of Amphotericin B for Oropharyngeal Candidiasis
Pharmaceutics, 2019 Amphotericin B possesses high activity against Candida spp. with low risk of resistance. However, Amphotericin B’s high molecular weight compared to other antifungal drugs, such as miconazole and clotrimazole, and poor water solubility hampers its ...
D. Serrano +4 more
semanticscholar +1 more source
Efficacy of combination therapy of amphotericin and posaconazole in treatment of mucormycosis
Journal of Applied Pharmaceutical Research, 2023 Background: Mucormycosis is an opportunistic systemic fungal infection which is debilitating caused by order Mucorales. The standard management of mucormycosis consists of aggressive debridement of the infected tissue and parenteral anti-fungal therapy ...
Sridhara S +4 more
doaj +1 more source
Modes of the antibiotic activity of amphotericin B against Candida albicans
Scientific Reports, 2019 Amphotericin B is an antibiotic used as the “gold standard” in the treatment of life-threatening fungal infections. Several molecular mechanisms have been proposed to explain exceptionally high effectiveness of amphotericin B in combating fungi.
Ewa Grela +7 more
semanticscholar +1 more source