Preventing or attenuating amphotericin B nephrotoxicity with dopamine receptor agonists: a literature review [PDF]
Trends in Pharmaceutical Sciences, 2015 Nephrotoxicity is generally considered as the most clinically significant and dose-limiting adverse reaction of amphotericin B. Currently, only the clinical effectiveness of salt loading and administering lipid formulations of amphotericin B have been ...
Iman Karimzadeh +2 more
doaj +2 more sources
Frontiers in Neurology, 2022 Liposomal amphotericin B (L-AMB) is an anti-fungus medicine that has fewer side effects than traditional amphotericin B (AMB). Neurotoxicity of L-AMB has rarely been observed, and only one case of leukoencephalopathy during intravenous L-AMB has been ...
Si Luo +4 more
doaj +1 more source
Comparative Chemotherapeutic Activity of Amphotericin B and Amphotericin B Methyl Ester [PDF]
Antimicrobial Agents and Chemotherapy, 1975 The comparative efficacy of amphotericin B and amphotericin B methyl ester (AME) against experimental histoplasmosis, blastomycosis, cryptococcosis, and candidosis in mice was assessed by determining the effect of daily intraperitoneal therapy on 21-day survival and persistence of organisms in internal organs. AME, like amphotericin B, was
Carl P. Schaffner +4 more
openaire +3 more sources
Changing pattern of visceral leishmaniasis, United Kingdom, 1985-2004. [PDF]
, 2006 A 20-year (1985-2004) retrospective review of 39 patients with imported visceral leishmaniasis found that tourism to Mediterranean countries and HIV infection were associated with visceral leishmaniasis. Diagnosis was often delayed.
Bruceson, Anthony DM +3 more
core +3 more sources
Amphotericin B in the management of COVID-19 associated mucormycosis [PDF]
, 2023 Background: Amphotericin B is considered the drug of choice for primary treatment of mucormycosis. During second wave of COVID-19 pandemic there was severe scarcity of liposomal amphotericin B. This study aims to determine role of various formulations of
Chandrashekar, Ravishankar +4 more
core +2 more sources
In-vitro and in-vivo antileishmanial activity of inexpensive Amphotericin B formulations: Heated Amphotericin B and Amphotericin B-loaded microemulsion [PDF]
Experimental Parasitology, 2018 Amphotericin B (AmB) is effective against visceral leishmaniasis (VL), but the renal toxicity of the conventional form, mixed micelles with deoxycholate (M-AmB), is often dose-limiting, while the less toxic lipid-based formulations such as AmBisome® are very expensive.
Rochelle, Andreza +11 more
openaire +4 more sources
Effects of Several Common Antifungal Drugs (Clotrimazole, Miconazole, Fluconazole) alone and in Combination with Amphotericin B on Candida Species Isolated from Chronic Candidal Vulvovaginitis [PDF]
Journal of Advanced Biomedical Sciences, 2014 Background; Objective: Candidal vulvovaginitis occurs in female genital by the over growth of candida especially candida albicans. This infection may be resistant to therapy and occasionally becomes chronic.
Efate alsadat shojaei +9 more
doaj +2 more sources
Efficacy of Systemic Treatment for Leishmania tropica Cutaneous Leishmaniasis
Acta Dermato-Venereologica, 2022 The effectiveness of systemic treatment for Leishmania tropica cutaneous leishmaniasis remains unclear. The purpose of the study is to evaluate the efficacy and safety of systemic treatments for L. tropica cutaneous leishmaniasis.
Michal Solomon +7 more
doaj +1 more source
Antifungal activity of amphotericin B conjugated to nanosized magnetite in the treatment of paracoccidioidomycosis [PDF]
, 2016 This study reports on in vitro and in vivo tests that sought to assess the antifungal activity of a newly developed magnetic carrier system comprising amphotericin B loaded onto the surface of pre-coated (with a double-layer of lauric acid) magnetite ...
A. Beduneau +60 more
core +2 more sources
Design of amphotericin B oral formulation for antifungal therapy
Drug Delivery, 2017 Amphotericin B (AmB) remains the “gold standard” for systemic antifungal therapy, even though new drugs are emerging as the attractive antifungal agents.
Min Liu, Meiwan Chen, Zhiwen Yang
semanticscholar +1 more source