Results 41 to 50 of about 232,371 (305)

Eradication, Strain Preservation, Strain Change — Outcomes of Helicobacter pylori Therapy

Антибиотики и Химиотерапия, 2021
Relevance. If we reduce the treatment exclusively to the eradication of Helicobacter pylori (Hp), the question of monitoring the results of anti-Hp therapy is controversial, given the widely known data on the detection of Hp, including virulent strains ...
E. V. Golubkina, V. M. Sorokin, B. N. Levitan, A. R. Umerova, N. V. Kamneva   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The molecular phenomena of the blaZ genes forming betalactamase enzymes structure in Staphylococcus aureus resistant to beta-lactam antibiotics (ampicillin)

Dental Journal, 2010
Background: Nowadays, infectious disease still an important problem. One of the bacteria causing infectious diseases is Staphylococcus aureus (S. aureus). In the effort to deal with infections caused by S.
Mieke Satari
doaj   +1 more source

Influence of Selected Factors on Biofilm Formation by Salmonella enterica Strains

Microorganisms, 2020
Biofilm formed by S. enterica on the surface of gallstones or biomaterials promotes the development and spread of chronic infection. The aim of the study was to assess biofilm formation on the surface of polystyrene depending on nutritional conditions ...
Agata Białucha, Eugenia Gospodarek-Komkowska, Joanna Kwiecińska-Piróg, Krzysztof Skowron   +3 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Celecoxib Enhances the Efficacy of Low-Dose Antibiotic Treatment against Polymicrobial Sepsis in Mice and Clinical Isolates of ESKAPE Pathogens

Frontiers in Microbiology, 2017
Treatment of multidrug resistant bacterial infections has been a great challenge globally. Previous studies including our study have highlighted the use of celecoxib, a non-steroidal anti-inflammatory drug in combination with antibiotic has decreased the
Madhavi Annamanedi, Gajapati Y. N. Varma, K. Anuradha, Arunasree M. Kalle   +3 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Iodometric determination of ampicillin in proprietary capsules

, 2010
The concentration of ampicillin in ampicillin capsule preparations purchased in Owerri main market, Imo State of Nigeria, was determined using the  iodometric titration method.
C Anunuso, A Ejele, N Anyanwu, Anunuso, C, Ejele, A, Anyanwu, N   +5 more
core   +1 more source

MD simulation of BLEG-1–ampicillin complex.

, 2023
(A) Root mean square deviation (RMSD) (left) and root mean square fluctuation (RMSF) (right) analyses of BLEG-1 (free form) (blue line) and BLEG-1–ampicillin complex (red line). Active site loops are labelled with asterisk (*) in the RMSF plot.
Hiroyoshi Matsumura (681222), Azyyati Mohd Padzil (16942988), Yahaya M. Normi (1375230), Shaw Xian Au (16942985), Noor Dina Muhd Noor (16942991), Raja Noor Zaliha Raja Abdul Rahman (16942994)   +5 more
core   +1 more source

Synergistic bactericidal activity of a naturally isolated phage and ampicillin against urinary tract infecting Escherichia coli O157 [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Bacteriophages are infectious replicating entities that are under consideration as antimicrobial bioagents to control bacterial infections.
Zahra Moradpour, Nesa Yousefi, Dorna Sadeghi, Abdollah Ghasemian   +3 more
doaj   +1 more source