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The Influence of Outer Membrane Protein on Ampicillin Resistance of Vibrio parahaemolyticus [PDF]

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2023
The antibiotic resistance of the food-borne pathogen Vibrio parahaemolyticus has attracted researchers’ attention in recent years, but its molecular mechanism remains poorly understood.
Xiangyu Meng   +6 more
doaj   +3 more sources

Beta-lactamase dependent and independent evolutionary paths to high-level ampicillin resistance [PDF]

open access: yesNature Communications
The incidence of beta-lactam resistance among clinical isolates is a major health concern. A key method to study the emergence of antibiotic resistance is adaptive laboratory evolution. However, in the case of the beta-lactam ampicillin, bacteria evolved
Rotem Gross   +4 more
doaj   +3 more sources

Resistance elicited by sub-lethal concentrations of ampicillin is partially mediated by quorum sensing in Pseudomonas aeruginosa

open access: yesEnvironment International, 2021
The rapid increase of antibiotic resistance is a serious challenge around the world. Antibiotics are present in various environments at sub-lethal concentrations, but how resistance emerges under sub-lethal conditions is not fully clear.
Yue Li   +6 more
doaj   +4 more sources

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model. [PDF]

open access: yesCell Rep, 2022
SUMMARY Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multidrug-resistance exceeding 80% and 40%, respectively.
Brazel EB   +18 more
europepmc   +2 more sources

The return of Pfeiffer's bacillus: Rising incidence of ampicillin resistance in Haemophilus influenzae. [PDF]

open access: yesMicrob Genom, 2018
Haemophilus influenzae, originally named Pfeiffer’s bacillus after its discoverer Richard Pfeiffer in 1892, was a major risk for global health at the beginning of the 20th century, causing childhood pneumonia and invasive disease as well as otitis media ...
Heinz E.
europepmc   +2 more sources

Basal level of ppGpp coordinates Escherichia coli cell heterogeneity and ampicillin resistance and persistence [PDF]

open access: yesMicrobial Cell, 2023
The universal stringent response alarmone ppGpp (guanosine penta and tetra phosphates) plays a crucial role in various aspects of fundamental cell physiology (e.g., cell growth rate, cell size) and thus bacterial tolerance to and survival of external ...
Paulina Katarzyna Grucela   +1 more
doaj   +2 more sources

Revisiting mutational resistance to ampicillin and cefotaxime in Haemophilus influenzae

open access: yesGenome Medicine
Background Haemophilus influenzae is an opportunistic bacterial pathogen that can cause severe respiratory tract and invasive infections. The emergence of β-lactamase-negative ampicillin-resistant (BLNAR) strains and unclear correlations between ...
Margo Diricks   +13 more
doaj   +2 more sources

Genome-wide identification of ampicillin resistance determinants in Enterococcus faecium. [PDF]

open access: yesPLoS Genetics, 2012
Enterococcus faecium has become a nosocomial pathogen of major importance, causing infections that are difficult to treat owing to its multi-drug resistance.
Xinglin Zhang   +6 more
doaj   +2 more sources

Fructose promotes ampicillin killing of antibiotic-resistant Streptococcus agalactiae

open access: yesVirulence, 2023
Streptococcus agalactiae (GBS) is an important pathogenic bacteria that infected both aquatic animals and human beings, causing huge economic loss. The increasing cases of antibiotic-resistant GBS impose challenges to treat such infection by antibiotics.
Xuan-Wei Chen   +4 more
doaj   +2 more sources

Ampicillin resistance in Haemophilus influenzae from COPD patients in the UK

open access: yesInternational Journal of COPD, 2017
Satyanarayana Maddi,1 Umme Kolsum,1 Sarah Jackson,1 Richard Barraclough,2 Barbara Maschera,3 Karen D Simpson,3 Thierry G Pascal,4 Serge Durviaux,4 Edith M Hessel,3 Dave Singh1 1Division of Infection, Immunity and Respiratory Medicine, Medicines ...
Maddi S   +9 more
doaj   +2 more sources

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