Results 211 to 220 of about 117,713 (263)

Amino acid insufficiency orchestrates AMPK and mTOR signaling. [PDF]

Fundam Res
Li T, Zhao L, Jia D.
europepmc   +1 more source

The myokine irisin ameliorates the secretory dysfunction of pancreatic β cells in experimental and human type 2 diabetes. [PDF]

Sci Adv
Marrano N, Borrelli A, Biondi G, Rella M, D'Oria R, Genchi VA, Caccioppoli C, Galasso V, Galluzzi G, Roberto L, Signorile A, Vincenti L, Aquilino F, Nano R, Baruzzi F, Moretti A, Lupo LG, Marchetti P, Piemonti L, Cignarelli A, Perrini S, Laviola L, Giorgino F, Natalicchio A.   +23 more
europepmc   +1 more source

AMPK-mediated autophagy induction by bisdemethoxycurcumin attenuates senescence and amyloid pathology in 3xTg-AD mice. [PDF]

Autophagy Rep
Khajuria P, Kour D, Sharma K, Singh L, Banoo R, Manhas D, Ramajayan P, Nandi U, B Bharate S, Ahmed Z, Kumar A.   +10 more
europepmc   +1 more source

Nobiletin Protects Endothelial Function in High-Fat Diet-Induced Obese Mice Through Activation of 5' Adenosine Monophosphate-Activated Protein Kinase. [PDF]

Nutrients
Deng Q, Wang Y, Yang Y, Miao L, Zhong C, Fu M, Cheang WS.   +6 more
europepmc   +1 more source

VCPIP1 drives diabetic cardiomyopathy by deubiquitinating AMPKγ1 and preventing AMPKα-γ subunit assembly in cardiomyocytes. [PDF]

Signal Transduct Target Ther
Han X, Huang Z, Liu G, Liu Y, Li W, Zheng J, Tong J, He M, Wu Y, Li Z, Luo W, Shi Q, Ying H, Liang G.   +13 more
europepmc   +1 more source

Inhibition of TWEAK/Fn14 Ameliorates Sarcopenic Obesity by Restoring Mitochondrial Biogenesis via the AMPK/SIRT1/PGC-1α Axis. [PDF]

Diabetes Metab Syndr Obes
Xuekelati S, Maimaitiwusiman Z, Guo Y, Guo S, Xu Q, Ke J, Xu L, Yang Y, Wang H.   +8 more
europepmc   +1 more source

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AMPK and vasculoprotection

Pharmacology & Therapeutics, 2011
AMP-activated protein kinase (AMPK) is proposed to be a key regulator of cellular and organismal metabolism and has reported vasculoprotective effects. In addition, many therapeutic agents used in the treatment of diabetes and atherosclerosis such as metformin, thiazolidinediones and statins may exert their vasculoprotective effects through activation ...
Marie-Ann, Ewart, Simon, Kennedy
openaire   +2 more sources

AMPK and the Adaptation to Exercise

Annual Review of Physiology, 2022
Noncommunicable diseases are chronic diseases that contribute to death worldwide, but these diseases can be prevented and mitigated with regular exercise. Exercise activates signaling molecules and the transcriptional network to promote physiological adaptations, such as fiber type transformation, angiogenesis, and mitochondrial biogenesis.
Hannah R, Spaulding, Zhen, Yan
openaire   +2 more sources