Results 111 to 120 of about 549,161 (310)
Modelling of two-, threesection TWT of O-type of teraherts band frequencies
A analysis of physical processes in TWT on folded waveguide with a consecutive and parallel arrangement of sections concerning electronic beams is carried out. Features and advantages of different construction of amplifiers are noted.
A. V. Aksenchyk +2 more
doaj
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The main results of the researches in the scientific direction «Modeling and optimizing nonlinear electromagnetic processes» for 2013-2018 years are presented.
A. A. Kurayev, V. V. Matveyenka
doaj
Design and Realization of Ultra-Wideband Differential Amplifiers for M-Sequence Radar Applications
Amplification of wideband high-frequency and microwave signals is a fundamental element within every high-frequency circuit and device. Ultra-wideband (UWB) sensor applications use circuits designed for their specific application.
Miroslav Sokol +2 more
doaj +1 more source
Transient augmentation circuit for pulse amplifiers Patent [PDF]
Digital data handling circuits for pulse ...
Benedict, R. D.
core +1 more source
Passive alignment stability and auto-alignment of multipass amplifiers based on Fourier transforms
The stability properties of Fourier-based multipass amplifier to misalignments (tilts) of its optical components has been investigated. For this purpose, a method to quantify the sensitivity to tilts based on the amplifier small signal gain has been ...
Antognini, Aldo +10 more
core +3 more sources
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Temperature sensitive oscillator [PDF]
An oscillator circuit for sensing and indicating temperature by changing oscillator frequency with temperature comprises a programmable operational amplifier which is operated on the roll-off portion of its gain versus frequency curve and has its output ...
Kleinberg, L. L.
core +1 more source
We demonstrate a lumped-element Josephson parametric amplifier, using a single-ended design that includes an on-chip, high-bandwidth flux bias line. The amplifier can be pumped into its region of parametric gain through either the input port or through ...
Barends, Rami +20 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source

