Results 111 to 120 of about 919,177 (398)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Bandwidth-Tunable Optical Amplifier with Narrowband Filtering Function Enabled by Parity-Time Symmetry at Exceptional Points

open access: yesPhotonics
Integrated optical amplifiers are the building blocks of on-chip photonic systems, and they are often accompanied by a narrowband filter to limit noise.
Kunpeng Zhu   +4 more
doaj   +1 more source

A 24-GHz, +14.5-dBm fully integrated power amplifier in 0.18-μm CMOS [PDF]

open access: yes, 2005
A 24-GHz +14.5-dBm fully integrated power amplifier with on-chip 50-[ohm] input and output matching is demonstrated in 0.18-μm CMOS. The use of substrate-shielded coplanar waveguide structures for matching networks results in low passive loss and small ...
Hajimiri, Ali   +2 more
core  

A SQUID-based microwave cavity search for dark-matter axions

open access: yes, 2009
Axions in the micro eV mass range are a plausible cold dark matter candidate and may be detected by their conversion into microwave photons in a resonant cavity immersed in a static magnetic field.
Asztalos, S. J.   +14 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Automatic quadrature control and measuring system [PDF]

open access: yes, 1973
Quadrature is separated from amplified signal by use of phase detector, with phase shifter providing appropriate reference. Output of phase detector is further amplified and filtered by dc amplifier.
Hamlet, J. F.
core   +2 more sources

Integrated Optical Amplifier–Photodetector on a Wearable Nanocellulose Substrate [PDF]

open access: bronze, 2018
Isaac Suárez   +8 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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