Results 61 to 70 of about 371,406 (280)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Piggybacking Codes for Network Coding: The High/Low SNR Regime

open access: yes, 2017
We propose a piggybacking scheme for network coding where strong source inputs piggyback the weaker ones, a scheme necessary and sufficient to achieve the cut-set upper bound at high/low-snr regime, a new asymptotically optimal operational regime for the
Ghanem, Samah A. M.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Enhanced Amplify-and-Forward Relaying in Non-Gaussian PLC Networks

open access: yesIEEE Access, 2017
Relaying over power line communication (PLC) channels has the potential to improve the reliability and robustness of many PLC-based applications. In particular, this paper proposes to enhance the energy efficiency (EE) of a dual-hop relaying PLC system ...
Khaled M. Rabie, Bamidele Adebisi
doaj   +1 more source

Ergodic capacity of the exponentially correlated slotted amplify and forward relay channel [PDF]

open access: yes, 2012
In this paper we analyze the performance degradation of slotted amplify-and-forward protocol in wireless environments with high node density where the number of relays grows asymptotically large.
Jayalath, Dhammika   +2 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Exploiting Sparsity in Amplify-and-Forward Broadband Multiple Relay Selection

open access: yesIEEE Access, 2019
Cooperative communication has attracted significant attention in the last decade due to its ability to increase the spatial diversity order with only single-antenna nodes.
Ala Gouissem   +3 more
doaj   +1 more source

Hardware Impairments Aware Transceiver Design for Full-Duplex Amplify-and-Forward MIMO Relaying

open access: yes, 2017
In this work we study the behavior of a full-duplex (FD) and amplify-and-forward (AF) relay with multiple antennas, where hardware impairments of the FD relay transceiver is taken into account.
Cirik, Ali Cagatay   +2 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Outage Capacity of Bursty Amplify-and-Forward with Incremental Relaying

open access: yes, 2010
We derive the outage capacity of a bursty version of the amplify-and-forward (BAF) protocol for small signal-to-noise ratios when incremental relaying is used.
Goldsmith, Andrea   +4 more
core   +1 more source

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