Results 71 to 80 of about 328,660 (289)

Association Between Sodium-Glucose Cotransporter 2 Inhibitors and Lower Extremity Amputation Among Patients With Type 2 Diabetes

JAMA Internal Medicine, 2018
Importance Results of clinical trials suggest that canagliflozin, a sodium-glucose cotransporter 2 (SGLT-2) inhibitor for treating type 2 diabetes, may be associated with lower extremity amputation.
Hsien-Yen Chang, Sonal Singh, O. Mansour, S. Baksh, G. C. Alexander   +4 more
semanticscholar   +1 more source

Quantifying the incidence of lower limb amputation in people with and without diabetes in Wales between 2008–2018

Diabetes Epidemiology and Management, 2023
Background: There is variance in the incidence of lower extremity amputation across and within countries including within the UK. National data shows up to a fourfold variance in the amputation rate throughout the regions of England and differences in ...
J Hayes, JM Rafferty, WY Cheung, A Akbari, R Thomas, S Bain, C Topliss, JW Stephens   +7 more
doaj   +1 more source

Sensory Changes in Adults with Unilateral Transtibial Amputation [PDF]

, 1998
The purpose of this study was to describe the sensory changes in adults with unilateral transtibial amputation (TTA), as any loss of sensation may have significant impact on the successful use of a prosthesis.
Kosasih, Judith B., Silver-Thorn, Barbara   +1 more
core   +1 more source

From satisfaction to expectation: The patient's perspective in lower limb prosthetic care [PDF]

, 2007
Neck pain is a common musculoskeletal complaint and a relationship with reduced work-related functional capacity is assumed. A validated instrument to test functional capacity of patients with neck pain is unavailable.
Geertzen, J.H.B., Hofstad, C.J., Postema, K., van der Linde, H., van Limbeek, J.   +4 more
core   +2 more sources

Population-based secular trends in lower-extremity amputation for diabetes and peripheral artery disease

Canadian Medical Association Journal, 2019
BACKGROUND: The evolving clinical burden of limb loss secondary to diabetes and peripheral artery disease remains poorly characterized. We sought to examine secular trends in the rate of lower-extremity amputations related to diabetes, peripheral artery ...
M. Hussain, M. Al-Omran, K. Salata, A. Sivaswamy, T. Forbes, N. Sattar, B. Aljabri, Ahmed Kayssi, S. Verma, C. de Mestral   +9 more
semanticscholar   +1 more source

Comparing the mechanical energetics of walking among individuals with unilateral transfemoral limb loss using socket and osseointegrated prosthetic interfaces

Scientific Reports
Osseointegration (OI), or bone-anchoring, of a prosthesis is a transformative procedure for addressing issues of socket fit among individuals with lower limb loss. Mechanically, the removal of the socket interface substantially alters the transmission of
Pawel R. Golyski, Benjamin K. Potter, Jonathan A. Forsberg, Brad D. Hendershot   +3 more
doaj   +1 more source

BMP9 stimulates joint regeneration at digit amputation wounds in mice

Nature Communications, 2019
A major goal of regenerative medicine is to stimulate tissue regeneration after traumatic injury. We previously discovered that treating digit amputation wounds with BMP2 in neonatal mice stimulates endochondral ossification to regenerate the stump bone.
Ling Yu, Lindsay A Dawson, Mingquan Yan, Katherine Zimmel, Yu-Lieh Lin, Connor P. Dolan, Manjong Han, K. Muneoka   +7 more
semanticscholar   +1 more source

The Association Between Sleep Duration and Clinical Measures of Concussion at Baseline and Postinjury in the United States Service Academy Cadets and Midshipmen

Neurotrauma Reports
The purpose of this study was to examine the relationship between sleep duration and clinical concussion assessments across concussion management timepoints in service academy cadets and midshipmen.
Michael J. Aderman, Megan H. Roach, Steven R. Malvasi, Jeremy Ross, Steven J. Svoboda, Joel B. Robb, Gerald T. McGinty, Jonathan C. Jackson, Darren E. Campbell, Carlos A. Estevez, Rachel Brodeur, Kathryn Van Pelt, Adam Susmarski, Steven Broglio, Michael McCrea, Thomas W. McAllister, Paul F. Pasquina, Kenneth L. Cameron   +17 more
doaj   +1 more source

The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration. [PDF]

, 2015
The control of proliferation and differentiation by tumor suppressor genes suggests that evolution of divergent tumor suppressor repertoires could influence species regenerative capacity.
Ahituv, Nadav, Hesse, Robert, Kouklis, Gayle, Pomerantz, Jason   +3 more
core   +1 more source

Transmetatarsal Amputation Results in Higher Frequency of Revision Surgery and Higher Ambulation Rates Than Below-Knee Amputation

Foot & Ankle Orthopaedics, 2022
Background: Selecting the level of amputation for patients with severe foot pathology can be challenging. The surgeon is sometimes confronted with an option between transmetatarsal amputation (TMA) and below-knee amputation (BKA).
Angel Ordaz MD, Conner Trimm BS, Jason Pedowitz MD, Ian M. Foran MD   +3 more
doaj   +1 more source