Results 61 to 70 of about 279,658 (282)

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Primate Amygdalo-Nigral Pathway for Boosting Oculomotor Action in Motivating Situations

iScience, 2020
Summary: A primary function of the primate amygdala is to modulate behavior based on emotional cues. To study the underlying neural mechanism, we first inactivated the amygdala locally and temporarily by injecting a GABA agonist.
Kazutaka Maeda, Ken-ichi Inoue, Jun Kunimatsu, Masahiko Takada, Okihide Hikosaka   +4 more
doaj   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Maternal cortisol is associated with neonatal amygdala microstructure and connectivity in a sexually dimorphic manner

eLife, 2020
The mechanisms linking maternal stress in pregnancy with infant neurodevelopment in a sexually dimorphic manner are poorly understood. We tested the hypothesis that maternal hypothalamic-pituitary-adrenal axis activity, measured by hair cortisol ...
David Q Stoye, Manuel Blesa, Gemma Sullivan, Paola Galdi, Gillian J Lamb, Gill S Black, Alan J Quigley, Michael J Thrippleton, Mark E Bastin, Rebecca M Reynolds, James P Boardman   +10 more
doaj   +1 more source

Following one's heart: cardiac rhythms gate central initiation of sympathetic reflexes [PDF]

, 2009
Central nervous processing of environmental stimuli requires integration of sensory information with ongoing autonomic control of cardiovascular function.
Critchley, Hugo D, Gray, Marcus A, Harrison, Neil A, Rylander, Karin, Wallin, B Gunnar   +4 more
core   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

Advanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy, Heta Helakari, Tommi Väyrynen, Zalán Rajna, Niko Huotari, Lauri Raitamaa, Ville Isokoski, Matti Järvelä, Mika Kaakinen, Johanna Piispala, Mika Kallio, Vesa Korhonen, Tapio Seppänen, Vesa Kiviniemi   +13 more
wiley   +1 more source

Afraid of the dark: Light acutely suppresses activity in the human amygdala.

PLoS ONE, 2021
Light improves mood. The amygdala plays a critical role in regulating emotion, including fear-related responses. In rodents the amygdala receives direct light input from the retina, and light may play a role in fear-related learning.
Elise M McGlashan, Govinda R Poudel, Sharna D Jamadar, Andrew J K Phillips, Sean W Cain   +4 more
doaj   +1 more source

Hippocampal and amygdala volumetry by MRI in elderly with normal or mildly impaired cognition using FreeSurfer software

Journal of the Mexican Federation of Radiology and Imaging, 2023
Introduction. Decreased hippocampal and amygdala volume has been associated with cognitive impairment. This study compared hippocampal and amygdala volumes in older adults with normal cognition and mild cognitive impairment (MCI) using magnetic resonance
Paloma F. Vazquez-Jimenez, Monica Rios-Silva, Efren Murillo-Zamora, Jaime A. Bricio-Barrios, Oscar R. Marrufo-Melendez, Miguel Huerta   +5 more
doaj   +1 more source

Insecure attachment during infancy predicts greater amygdala volumes in early adulthood [PDF]

, 2014
Background The quality of the early environment is hypothesized to be an influence on morphological development in key neural areas related to affective responding, but direct evidence to support this possibility is limited.
Ahnert, Ainsworth, Baare, Barros-Loscertales, Baur, Bowlby, Brain Development Cooperative Group, Caetano, Caldji, Campbell, Cassidy, Chen, Cox, Dedovic, Erp, Fearon, Fox, Free, Gerritsen, Groh, Gunnar, Halligan, Hertsgaard, Holmes, Huang, Huot, Kaufman, Ladd, Ladouceur, Luby, Lupien, Lupien, MacMaster, MacMillan, Main, McCrory, Meaney, Mehta, Morey, Moutsiana, Munn, Murray, Murray, Murray, Ono, Pannekoek, Qin, Raineki, Rao, Rao, Romanczuk-Seiferth, Rorden, Rosso, Smith, Smith, Spangler, Spitzer, Spitzer, Tottenham, Videbech, Whalen, Wolff, Woolrich   +62 more
core   +2 more sources