Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats. [PDF]
, 2019 The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats.
Crawford, Elena +8 more
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Impaired contextual modulation of memories in PTSD: an fMRI and psychophysiological study of extinction retention and fear renewal [PDF]
, 2014 Post-traumatic stress disorder (PTSD) patients display pervasive fear memories, expressed indiscriminately. Proposed mechanisms include enhanced fear learning and impaired extinction or extinction recall. Documented extinction recall deficits and failure
Abelson, James L +6 more
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Serotonergic innervation of the amygdala is increased in autism spectrum disorder and decreased in Williams syndrome. [PDF]
, 2020 BackgroundWilliams syndrome (WS) and autism spectrum disorder (ASD) are neurodevelopmental disorders that demonstrate overlapping genetic associations, dichotomous sociobehavioral phenotypes, and dichotomous pathological differences in neuronal ...
Bellugi, U +8 more
core
The emotional gatekeeper: a computational model of attentional selection and suppression through the pathway from the amygdala to the inhibitory thalamic reticular nucleus [PDF]
, 2016 In a complex environment that contains both opportunities and threats, it is important for an organism to flexibly direct attention based on current events and prior plans. The amygdala, the hub of the brain's emotional system, is involved in forming and
Barbas, Helen +3 more
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Visual search for basic emotional expressions in autism: impaired processing of anger, fear and sadness, but a typical happy face advantage [PDF]
, 2010 Facial expression recognition was investigated in 20 males with high functioning autism (HFA) or Asperger syndrome (AS), compared to typically developing individuals matched for chronological age (TD CA group) and verbal and non-verbal ability (TD V/NV ...
Abell +42 more
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, 2007 The amygdala is made up of several heterogeneous nuclei in the medial temporal lobe. It is anatomically situated to receive a wide variety of processed sensory information from both the environment and body. It also has the requisite projections to influence virtually all the behavioral, autonomic and hormonal components of stress.
Fanselow, MS, Ponnusamy, R
openaire +2 more sources
NeuroImageMammals rely heavily on their auditory system to perceive environmental threats, socially communicate, and care for the young. As an extension of the multiple sensory system including the auditory system, the amygdala evaluates the emotional salience of ...
Qianbing Li +7 more
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Brain and Behavior, 2020 Introduction Resting state functional magnetic resonance imaging (rsfMRI) studies demonstrate that individuals with posttraumatic stress disorder (PTSD) exhibit atypical functional connectivity (FC) between the amygdala, involved in the generation of ...
Jacklynn M. Fitzgerald +4 more
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Amygdala fMRI—A Critical Appraisal of the Extant Literature
Neuroscience InsightsEven before the advent of fMRI, the amygdala occupied a central space in the affective neurosciences. Yet this amygdala-centred view on emotion processing gained even wider acceptance after the inception of fMRI in the early 1990s, a landmark that ...
Tim Varkevisser +2 more
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