Results 1 to 10 of about 3,951 (170)
Buyang Huanwu Decoction Alleviates Bleomycin-Induced Pulmonary Fibrosis via Wnt/β-catenin and TGF-β1/Smad Pathways. [PDF]
Chem BiodiversThe supernatant fraction of Buyang Huanwu Decoction, obtained by ethanol precipitation, demonstrates superior efficacy against pulmonary fibrosis. It enhances the bioavailability of key compounds and dually inhibits Wnt/β‐catenin and TGF‐β1/Smad pathways, presenting a potent therapeutic strategy.
Zhou Y +7 more
europepmc +2 more sources
Polyphasic Characterization of Acetobacter indonesiensis UNPADCC 01-5 Isolated From a Traditional Fermented Food, Oncom Merah. [PDF]
Environ Microbiol RepThe polyphasic approach (morphology, physiology, biochemistry and genetics) was used to characterize Acetobacter indonesiensis strain UNPADCC 01‐5, which was isolated from oncom merah. The strain's potential as a culture for acidic fermentations and a biofunctional agent was supported by its adaptive characteristics, which included acid tolerance ...
Syaputri Y +9 more
europepmc +2 more sources
Valorization of fruit pits from Prunus laurocerasus and Prunus cerasifera as agro-food byproducts: Bioactive properties and safety assessment for potential food additive applications. [PDF]
J Sci Food AgricAbstract BACKGROUND Food additives are widely used to extend the shelf life of foods and maintain their quality. In this study, the potential of Prunus laurocerasus and Prunus cerasifera fruit pits (endocarp and seed) as food additives was investigated in terms of cytotoxicity, antigenotoxicity, antioxidant activity, enzymatic anti‐browning, and urease
Güven ZB +4 more
europepmc +2 more sources
The pharmacokinetics of amygdalin [PDF]
Archives of Toxicology, 1982 Amygdalin (D-mandelonitrile-beta-D-gentiobioside) is a cyanogenic glycoside claimed to show anti-cancer activity, sold under the incorrect name "Laetrile". For a sensible discussion of its alleged activity and its established toxicity it is necessary that its fate in the organism is known. The pharmacokinetics of amygdalin have been investigated in the
Rauws, AG, Olling, M, Timmerman, A
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The enzymic hydrolysis of amygdalin [PDF]
Biochemical Journal, 1967 Chromatographic examination has shown that the enzymic hydrolysis of amygdalin by an almond beta-glucosidase preparation proceeds consecutively: amygdalin was hydrolysed to prunasin and glucose; prunasin to mandelonitrile and glucose; mandelonitrile to benzaldehyde and hydrocyanic acid. Gentiobiose was not formed during the enzymic hydrolysis.
D R, Haisman, D J, Knight
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CLXI.—The amygdalins. Part I [PDF]
J. Chem. Soc., Trans., 1909 n ...
Walker, J. Wallace, Krieble, Vernon K.
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Feiwei Heji Enhances Antitumor Immunity by MLL4‐Dependent Regulation of Pyroptosis in Lung Cancer
Cancer Science, EarlyView.Feiwei Heji suppresses lung tumor growth by downregulating MLL4 and activating caspase‐1/GSDMD‐associated pyroptosis. This pyroptosis‐related inflammatory response enhances CD8+ T‐cell‐mediated antitumor immunity, revealing an MLL4‐pyroptosis‐immune axis underlying the therapeutic activity of Feiwei Heji.
Nan Cheng +6 more
wiley +1 more source
Insect Molecular Biology, EarlyView.A chromosome‐level genome of Elcysma westwoodi was assembled. The genome encodes 272 detoxification‐related genes. A single‐copy bCAS was retained for cyanide detoxification. CYP405A and CYP332A were recruited into cyanogenic defence evolution. UGT33A retained a conserved GT‐B fold and catalytic domains.
Minyoung Choi, Murtaza Khan, Juil Kim
wiley +1 more source
Genomic variation drives plant flavor diversification
Journal of Integrative Plant Biology, EarlyView.This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu +5 more
wiley +1 more source