Results 221 to 230 of about 202,609 (344)

Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk

open access: yesCell Proliferation, EarlyView.
This graphical abstract illustrates the reciprocal crosstalk between the brain and peripheral organs, highlighting the profound impact of exercise on brain health through systemic interactions. It underscores how exercise influences the brain via signals from various organs and, conversely, how the brain modulates functions of peripheral organs.
Shirin Pourteymour   +3 more
wiley   +1 more source

Efficacy and safety of danuglipron (PF‐06882961) in adults with obesity: A randomized, placebo‐controlled, dose‐ranging phase 2b study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This randomized, double‐blind, placebo‐controlled Phase 2b study aimed to assess the efficacy, safety, and tolerability of danuglipron (PF‐06882961), an oral small‐molecule glucagon‐like peptide‐1 (GLP‐1) receptor agonist, in adults with obesity. Materials and Methods Eligible participants (aged 18–75 years; with obesity, without diabetes)
Clare Buckeridge   +9 more
wiley   +1 more source

Incretin system and glucagon secretion in patients with chronic pancreatitis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Diabetes of the exocrine pancreas (DEP) showed unclear incretin and glucagon dynamics. This cross‐sectional study compared 32 patients with chronic pancreatitis (wCP) and 60 without (w/oCP). Subjects wCP had worse beta‐cell function and lower incretin effect.
Gea Ciccarelli   +16 more
wiley   +1 more source

Diagnostic approach to chronic diarrhoea in adult horses

open access: yesEquine Veterinary Education, Volume 37, Issue 6, Page 328-336, June 2025.
Summary Chronic diarrhoea presents a diagnostic challenge for both human physicians and equine veterinarians. There is currently no consensus in the equine veterinary literature on the definition of chronic diarrhoea. The differential list is extensive and identifying diarrhoea by pathophysiologic mechanism can help remove less likely diagnoses ...
E. Sjolin, A. Lack, L. G. Arroyo
wiley   +1 more source

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