Results 191 to 200 of about 27,274 (288)

Enhancing Cold Adaptation of Bidomain Amylases by High-Throughput Computational Engineering. [PDF]

Angew Chem Int Ed Engl
Ding N, Jiang Y, Ge R, Shao Q, Shin W, Ran X, Yang ZJ.   +6 more
europepmc   +1 more source

Structural analysis of the NifL‐NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii

The FEBS Journal, EarlyView.
Using cryo‐EM combined with biochemical and genetic approaches, we mapped the interaction surface between NifL and NifA to gain insights into the regulation of nitrogen fixation genes in A. vinelandii. Our findings suggest that NifL, a homolog of histidine kinases lacking phosphorylation activity, evolved to act as a steric block of NifA activity ...
Marcelo Bueno Batista, Jake Richardson, Michael W. Webster, Dmitry Ghilarov, John W. Peters, David M. Lawson, Ray Dixon   +6 more
wiley   +1 more source

MalS, a periplasmic α-amylase in Escherichia coli, has a binding affinity to glycogen with unique substrate specificities. [PDF]

Appl Microbiol Biotechnol
Tran PL, Yoo M, Kim SG, Park JT.
europepmc   +1 more source

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source

Bacillus subtilis T7 encodes [FeFe]-hydrogenase and lignin-targeting LPMOs for consolidated bioprocessing. [PDF]

Appl Microbiol Biotechnol
Iqbal W, Cai H, Li Z, Zhang J, Yang K, Han X, Chuancheng D, Zhang A, Anwar Y, Ullah I, Shah TA.   +10 more
europepmc   +1 more source

Characterisation of a cold‐adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS‐131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation

The FEBS Journal, EarlyView.
We investigated glucokinase from the psychrophilic Pseudoalteromonas sp. AS‐131 (PsGK), which was isolated from the Antarctic Ocean. Biochemical studies revealed that PsGK is a cold‐adapted enzyme with high thermal stability, in contrast to general cold‐adapted enzymes, which have low thermal stability.
Akane Yato, Yuki Kato, Fuyuko Hayashi, Rio Asaka, Atsuko Ogawa, Tokuro Oda, Sayaka Tsuji, Masashi Unno, Nobuaki Soh, Keiichi Watanabe, Masaki Horitani   +10 more
wiley   +1 more source

<i>Parageobacillus</i> and <i>Geobacillus</i> spp.: From Food Spoilage to Beneficial Food Applications. [PDF]

Foods
Salvador M, Condón S, Gayán E.
europepmc   +1 more source

Steatotic Liver Disease: A Key Related Risk Factor in the Emergence of Metabolic Syndrome‐Related Disorders

Hepatology Research, EarlyView.
It is speculated that the onset of obesity‐related diseases follows the sequence of obesity → SLD → MetS‐related diseases. In this study, the contribution of SLD to each MetS‐related disease was large for T2D and hypertension and SLD contributed to the onset and new onset of the disease by the 7‐year follow‐up.
Yoshihiro Kamada, Makoto Fujii, Hitoshi Nishizawa, Shiro Fukuda, Makoto Yamada, Iichiro Shimomura, Eiji Miyoshi   +6 more
wiley   +1 more source

Complete genome sequencing of Bacillus velezensis Jin12 revealed its great ability for starch degradation in flue-cured tobacco leaves. [PDF]

BMC Microbiol
Yang Y, Yang M, Zhang Y, Yang B, Miao C, Liang T, Xu Q, Hu L, Hu Z.   +8 more
europepmc   +1 more source

Peritoneal Sarcoidosis

ANZ Journal of Surgery, EarlyView.
Luiz Eduardo Correia Miranda, André Bezerra de Sena, Raphael Brito Vieira   +2 more
wiley   +1 more source