Results 171 to 180 of about 16,804 (299)

Clinical Significance of a Cell‐Of‐Origin‐Based Classification in Pancreatic Ductal Adenocarcinoma

open access: yesCancer Science, EarlyView.
Schematic overview of a cell‐of‐origin‐based classification of pancreatic ductal adenocarcinoma (PDAC), highlighting distinct biological features and therapeutic implications of Acinar‐ and Ductal‐subtypes. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with limited therapeutic options and poor clinical ...
Tatsuya Kikuchi   +21 more
wiley   +1 more source

Understanding and modifying starch metabolism to limit yield losses in field-grown cassava. [PDF]

open access: yesPlant Physiol
David LC   +13 more
europepmc   +1 more source

High Specificity of sIgE to α−/β‐Gliadin and Limited Reactivity to Non‐Gluten Proteins in Wheat Allergy Dependent on Augmentation Factors (WALDA)

open access: yesClinical &Experimental Allergy, EarlyView.
This study suggest that WALDA is characterized by highly specific reactivity to gliadin proteins, with limited sensitization to non‐gluten wheat components. sIgE to α‐/β‐gliadin represents a promising diagnostic biomarker with superior specificity compared to ω5‐gliadin alone.
Valentina Faihs   +7 more
wiley   +1 more source

Mechanistic insights into substrate-targeting modification effects on interfacial kinetics of raw starch-degrading amylases. [PDF]

open access: yesAppl Environ Microbiol
Zhong L   +12 more
europepmc   +1 more source

A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy

open access: yesClinical Genetics, EarlyView.
PIP5K1C‐related lethal congenital contracture syndrome with hyperinsulinism and optic atrophy. ABSTRACT Lethal congenital contracture syndrome 3 (LCCS3, MIM #611369) is a rare autosomal recessive neuromuscular disorder caused by biallelic loss‐of‐function (LOF) variants in PIP5K1C, reported in only two families to date.
Tameemi Abdalla Moady   +3 more
wiley   +1 more source

Sensitization profiles in patients with wheat‐dependent exercise‐induced anaphylaxis: practical aspects for allergy workup

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Wheat‐dependent exercise‐induced anaphylaxis (WDEIA) occurs after ingestion of wheat/gluten in the presence of various cofactors. Here, we characterized the sensitization spectrum to various wheat flours, as revealed by skin prick test (SPT) and specific IgE (sIgE) against wheat flour, gluten, and various wheat components.
Enna M. Schwarze   +3 more
wiley   +1 more source

Design and Heterologous Production of Bagworm Silk-Inspired Proteins in <i>Aspergillus oryzae</i>. [PDF]

open access: yesComput Struct Biotechnol J
Dilokpimol A   +11 more
europepmc   +1 more source

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