Results 41 to 50 of about 11,774 (158)

Correlations between endogen amylin hormone and some hormonal, biochemical and bone parameters in pullets

open access: yesBrazilian Journal of Poultry Science, 2014
The objective of this study was to assess the correlations of amylin (a pancreatic polypeptide hormone) with some hormonal, biochemical and bone parameters in pullets. Forty 18-week-old pullets were used.
S Guzel, N Gunes
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Structural details of the single and double layer decamers of rat amylin, human amylin and rat-human amylin mixtures.

open access: yes, 2014
(A) Single layer conformation of human amylin, (B) single layer conformation of rat amylin, (C) single layer conformation of human-rat complex, (D) Double layer conformation of human amylin with CC interface (E) Double layer conformation of rat amylin ...
Workalemahu M. Berhanu (314489)   +1 more
core   +1 more source

Pramlintide (Amylin)

open access: yes, 2001
Pramlintide is a human amylin analog, under development by Amylin (originally in collaboration with Johnson & Johnson), as an adjunct with insulin for the potential prevention of complications of type I diabetes, and as a single agent for type II ...
D. Barlocco
core   +2 more sources

Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells

open access: yesRedox Biology, 2023
Diabetes mellitus currently affects ∼10% of the population worldwide, with Type 2 predominating, and this incidence is increasing steadily. Both Type 1 and 2 are complex diseases, involving β-cell death and chronic inflammation, but the pathways involved
Ramona Clemen   +3 more
doaj   +1 more source

Non‐Nutritive Artificial Sweeteners Aspartame and Acesulfame‐K Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease in Male Ldlr−/− Mice

open access: yesiNew Medicine, EarlyView.
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu   +3 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Protecting CEACAM1 Expression Prevents Diet‐Induced Metabolic Dysfunction and Hepatic Fibrosis in Male Mice

open access: yesObesity, EarlyView.
ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour   +9 more
wiley   +1 more source

Amylin and gastrointestinal activity

open access: yes, 1998
1. Amylin is a new pancreatic islet peptide with a role in the maintenance of glucose homeostasis. 2. Amylin is predominantly present in the beta cells of the pancreas and to a lesser extent in the gastrointestinal tract and in the nervous system, where ...
F Guidobono, F. Guidobono
core   +1 more source

Brain Distribution and Sexually Dimorphic Expression of Amylin in Different Reproductive Stages of the Zebra Finch (Taeniopygia guttata) Suggest Roles of the Neuropeptide in Song Learning and Social Behaviour

open access: yesFrontiers in Neuroscience, 2020
The expression of the recently identified neuropeptide, amylin, is restricted in rodents to the postpartum preoptic area and may play a role in the control of parental behaviours and food intake.
Gergely Zachar   +10 more
doaj   +1 more source

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