Results 61 to 70 of about 11,774 (158)
, 2015 a) Aminoacid sequence of the human and murine amylin. In bold are the different aminoacid. Notice the similarity in sequence from aminoacid 1 to 17. The N-terminus is the Lys1, which comprises the α- and ε-aminogroup, the two unique primary aminogroups ...
Luiz Henrique Guerreiro (810965) +7 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend During GLP‐1RA treatment reduced appetite and energy intake, delayed gastric emptying, decreased visceral fat mass and improved glycaemic control contribute to weight loss. After treatment cessation these benefits are partially or completely reversed, resulting in weight regain, accompanied by increased appetite and energy intake,
Camille E. M. Piguet +2 more
wiley +1 more source
Amyloidogenicity, Cytotoxicity, and Receptor Activity of Bovine Amylin: Implications for Xenobiotic Transplantation and the Design of Nontoxic Amylin Variants [PDF]
, 2018 Islet amyloid formation contributes to β-cell death and dysfunction in type-2 diabetes and to the failure of islet transplants. Amylin (islet amyloid polypeptide, IAPP), a normally soluble 37 residue polypeptide hormone produced in the pancreatic β-cells,
Debbie L. Hay +17 more
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Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.Bibliometric analysis of 3736 publications (2004–2025) reveals rapid growth in GLP‐1–based T2DM research. The US leads, with Novo Nordisk and Eli Lilly as top contributors. Thematic shifts from glycemic control toward cardiovascular‐kidney‐metabolic outcomes and real‐world evidence, driven by landmark trials like LEADER and REWIND.
Yanbing Wang +6 more
wiley +1 more source
Egyptian Rheumatology and Rehabilitation, 2018 Background Insulin resistance is found in Behçet’s disease and associated with the development of metabolic syndrome. Our study explored whether amylin, which is involved in insulin resistance and development of metabolic syndrome, is observed in ...
Shimaa M Abdelwhab +3 more
doaj +1 more source
The Journal of Headache and PainBackground The upper cervical dorsal root ganglia (DRG) are important for the transmission of sensory information associated with the back of the head and neck, contributing to head pain.
Tayla A. Rees +5 more
doaj +1 more source
Amylin and its Analogs: A Friend or Foe for the Treatment of Alzheimer’s Disease?
Frontiers in Aging Neuroscience, 2014 Amylin, a gut-brain axis hormone, and amyloid-beta peptides (Aβ), a major component of the Alzheimer’s disease (AD) brain, share several features, including similar β-sheet secondary structures, binding to the same receptor and being degraded by the same
Wei Qiao (Wendy) eQiu, Haihao eZhu
doaj +1 more source
Nutrition in Clinical Practice, Volume 41, Issue 5, Page 1318-1333, October 2026.Abstract Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonists have transformed the management of type 2 diabetes and obesity. Gastrointestinal (GI) adverse events are the most common limitation of these therapies and a leading cause of discontinuation ...
Vikash Singhani +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的探讨胰淀素（amylin）在肥胖相关性肾病（ORG）发展过程中的作用。方法 14例经肾活检证实的ORG患者为观察组（ORG组）,选择同期经肾活检确诊为系膜增生性肾小球肾炎患者作为相关疾病对照组（NC）。20只Wis-tar大鼠,高脂饮食诱导ORG大鼠模型,成模后随机均分为模型对照组（NC）和Amylin组（Amylin）。采用ELISA法检测血清amylin;放射免疫法检测胰岛素水平;自动生化分析仪测定血糖、血脂;考马斯亮蓝方法检测24小时尿蛋白定量;免疫组化法检测肾小球内amylin的表达。结果 ...
刘声茂 +6 more
doaj
Neuroscience ResearchThe pancreatic peptide amylin promotes negative energy balance in part through activation of amylin receptors (AmyRs) expressed in the ventral tegmental area (VTA), but studies have been limited to male rodents.
Tyler J. Gustafson +3 more
doaj +1 more source