Results 191 to 200 of about 514,761 (295)
Preoperative level of serum amyloid A is superior to C-reactive protein in the prognosis of esophageal squamous cell carcinoma [PDF]
, 2013 Yuqi Meng +7 more
openalex +1 more source
Advanced Science, EarlyView.A minimal computational model of cellular aggregate formation in neurodegenerative disease, encompassing two competing processes: cell‐autonomous and cell‐to‐cell triggers of aggregation, is presented. Despite its simplicity, the model can reproduce the aggregate patterns observed in post‐mortem brain images from the primary tauopathy Progressive ...
Shih‐Huan Huang +8 more
wiley +1 more source
3D-QSAR of PET Agents for Imaging β-Amyloid in Alzheimer's Disease [PDF]
, 2007 Mi Kyoung Kim +4 more
openalex +1 more source
Advanced Science, EarlyView.Through multiscale simulations and experimental approaches, the molecular determinants of α‐synuclein phase separation and condensate aging, which are linked to Parkinson's disease, are uncovered. Seven motifs are identified with high β‐sheet propensity in monomeric α‐synuclein and increasing β‐sheet tendencies during condensation and pre ...
Yiming Tang +11 more
wiley +1 more source
Unraveling the complexity of amyloid polymorphism using gold nanoparticles and cryo-EM [PDF]
, 2020 Urszula Cendrowska +14 more
openalex +1 more source
Advanced Science, EarlyView.Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao +11 more
wiley +1 more source
Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition
, 2017 Erwin Cabrera +7 more
openalex +2 more sources
Fatty acids and Alzheimer's Disease: Evidence on Cognition and Cortical β-amyloid from Secondary Analyses of the Multidomain Alzheimer Preventive Trial [PDF]
, 2018 Claudie Hooper, Bruno Vellas
openalex +1 more source
Advanced Science, EarlyView.Entropy derived from gray matter eigenmodes captures cortical disorganization in Alzheimer's disease. Using multimodal MRI and amyloid‐PET data, this novel structure–function coupling biomarker enables accurate classification of clinical stages, predicts Aβ burden, and stratifies mild cognitive impairment subtypes.
Yumeng Li +5 more
wiley +1 more source