Results 181 to 190 of about 405,002 (265)

Plasma Membrane Remodeling During Microglial Activation: A Hypothesis Linking Microglial Shape and Lipid Droplet Formation. [PDF]

Glia
Rebeck GW, Shautidze G, Sepulveda J, Healey GS, Narayan PS.   +4 more
europepmc   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Longitudinal Evaluation of ¹⁸F-MK-6240 Along the Alzheimer Disease Continuum. [PDF]

J Nucl Med
Giarratana AO, Jonaitis E, Przybelski RJ, Cody K, Betthauser TJ, Cadman R, Alberson SF, Christian BT, Johnson SC.   +8 more
europepmc   +1 more source

Protein‐Independent Liquid–Liquid Phase Separation of Adenosine Triphosphate Under Crowded Conditions

Chemistry – A European Journal, EarlyView.
ATP itself is able to undergo liquid–liquid phase separation in the presence of the macromolecular crowding agent PEG and physiological ATP concentrations are sufficient for phase separation in the presence of mM Mg2+ and crowders, mimicking intracellular conditions.
Robert Dec, Wojciech Dzwolak, Roland Winter   +2 more
wiley   +1 more source

Raman Optical Activity as a Tool to Monitor Polynucleotide Conformation in Solutions

Chemistry – A European Journal, EarlyView.
Raman optical activity (ROA) studies of nucleic acids have been hindered by limited computational tools to link the spectra to the structure. The study shows that accurate density functional simulations are possible for model nucleotides, bringing more information about molecular geometry and dynamics in solutions.
Mohammed Siddhique Para Kkadan, Josef Kapitán, Jiří Kessler, Ondřej Zapletal, Valery Andrushchenko, Petr Bouř   +5 more
wiley   +1 more source

Site-Specific Raman Probes Reveal Droplet Aging and Residue-Level Fibril Polymorphism in TDP-43_CTD. [PDF]

J Am Chem Soc
Watson MD, Lee JC.
europepmc   +1 more source

Amyloid Disease

International Journal of Clinical Practice, 1954
openaire   +2 more sources

Fibrilpaint: A Class of Amyloid‐Targeting Peptides

Chemistry – A European Journal, EarlyView.
FibrilPaints are modular peptides engineered to recognize amyloid fibrils. By systematically varying charge, sequence, and termini, their binding behavior can be tuned while retaining recognition. Successful binding ″paints″ fibrils for visualization and opens routes toward targeted degradation and diagnostic applications.
Júlia Aragonès Pedrola, Françoise A. Dekker, Katrin Guttmann, Litske M. van Leeuwen, Shalini Singh, Guy Mayer, Tommaso Garfagnini, Assaf Friedler, Stefan G. D. Rüdiger   +8 more
wiley   +1 more source

Abnormal amyloid PET usually represents intermediate/high Alzheimer's disease neuropathologic change. [PDF]

Alzheimers Dement
Burkett BJ, Wiste HJ, Johnson DR, Boeve BF, Kantarci K, Petersen RC, Knopman DS, Vemuri P, Graff-Radford J, Lowe V, Cogswell PM, Pillai J, Schwarz CG, Nguyen AT, Murray ME, Dickson DW, Jack CR.   +16 more
europepmc   +1 more source