Results 241 to 250 of about 646,127 (297)

The microtubule nexus linking amyloid beta and tau: A simple and unifying theory for the underlying cause of Alzheimer's disease. [PDF]

PNAS Nexus
Shoff TA, Derbez-Morin M, Cai P, Julian RR.   +3 more
europepmc   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

The 2024 NIA-AA biological definition of Alzheimer's disease: linking biomarkers to clinical practice. [PDF]

Front Dement
Kobayashi G, Hirata K, Ono M, Kasuga K, Takado Y.   +4 more
europepmc   +1 more source

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

ESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer, Mauro Contini, Michele Emdin, Damiano Magrì, Alice Bonomi, Elisabetta Salvioni, Fabrizio Celeste, Alberico Del Torto, Claudio Passino, Christophe D.J. Capelle, Chiara Arzilli, Emiliano Fiori, Nicolò Capra, Christina Kronberger, Nikita Ermolaev, Andreas Kammerlander, Beatrice Musumeci, Giuseppe Vergaro, Vincenzo Castiglione, René Rettl, Giacomo Tini, Andrea Baggiano, Iacopo Fabiani, Susanna Sciomer, Roza Badr Eslam, Piergiuseppe Agostoni   +25 more
wiley   +1 more source

Real-world diagnostic performance of blood-based biomarkers for Alzheimer's disease: robust performance except after stroke and high charlson comorbidity index. [PDF]

Alzheimers Res Ther
Vigneswaran S, Verberk IMW, Rousset RZ, Gouda M, Trieu C, Claessen T, de Giessen EV, Lemstra AW, Wilson D, Pijnenburg YAL, Flier WMV, Teunissen CE, Harten ACV.   +12 more
europepmc   +1 more source

Sex Differences in Amyloid Pathology by Race, Ancestry, and Apolipoprotein E ε4 in an Admixed Autopsy Sample.

JAMA Neurol
Abu Raya M, Suemoto CK, Paes VR, Leite REP, Pasqualucci CA, Naslavsky MS, Rodriguez RD, Nitrini R, Ferriolli E, Allen IE, La Joie R, Grinberg LT.   +11 more
europepmc   +1 more source

Predicting Brain Amyloid PET Positivity Using the Amyloid Beta Composite (ABC) Index in Patients With Cognitive Impairment. [PDF]

Dement Neurocogn Disord
Lee J, Jung S, Lee AY.
europepmc   +1 more source

CSF microtubule-associated protein 1 light chain 3A and 3B levels are associated with tau pathology and Alzheimer's disease risk through amyloid deposition and microglial signaling. [PDF]

J Neuroinflammation
Guo HH, Su D, Song B, Geng Z, Wang L, Wang W, Hu W, Li X, Li W, Zhang G, Fang M, Dai Y, Hu P, Wu X, Wang K, Wei L, Alzheimer’s Disease Neuroimaging Initiative.   +16 more
europepmc   +1 more source

Integration over reduction: multimodal PET and fluid biomarkers in Alzheimer's disease and beyond. [PDF]

Curr Opin Neurol
Bluma M, Chiotis K, Nordberg A.
europepmc   +1 more source

Ventricular enlargement is associated with early Alzheimer's disease pathophysiology. [PDF]

Brain Commun
Hosseini SA, Aumont E, Rahmouni N, Woo MS, Macedo AC, Hall B, Trudel L, Chan T, Fernandez Arias J, Wang YT, Servaes S, Therriault J, Zheng Y, Socualaya KQ, Bezgin G, Tissot C, Oliva-Lopez D, Hopewell R, Hsiao CH, Saleh C, Stevenson J, Lussier F, Wu L, Chu M, Chawla S, Fonov V, Massarweh G, Iturria-Medina Y, Soucy JP, Rudko DA, Gauthier S, Karikari T, Benedet AL, Ashton NJ, Zetterberg H, Montembeault M, Vitali P, Blennow K, Collins DL, Klostranec J, Pascoal TA, Rosa-Neto P.   +41 more
europepmc   +1 more source