Elevated amyloid beta peptides and total tau in cerebrospinal fluid in individuals with Creatine transporter deficiency. [PDF]
Mol Genet Metab Rep, 2023 Rahhal S +14 more
europepmc +1 more source
Fractal Scaling of Cortical Matter, Amyloid Fragmentation and Plaque Formation across Rodents and Primates [PDF]
arXiv, 2014 Thermodynamic tools are well suited to connecting evolution of protein functionalities to mutations of amino acid sequences, especially for neuronal network structures. These tools enable one to quantify changes in modular structure and correlate them with corresponding changes in observable properties.
arxiv
Amyloid-Beta Peptides 40 and 42 Employ Distinct Molecular Pathways for Cell Entry and Intracellular Transit at the Blood-Brain Barrier Endothelium. [PDF]
Mol Pharmacol, 2023 Wang Z +4 more
europepmc +1 more source
Quantitative diagnosis of amyloid without Congo red staining using polarized light microscopy [PDF]
arXivAmyloidosis is a protein misfolding disease caused by the deposition of large, insoluble aggregates (amyloid fibrils) of protein in a tissue, which has been associated with various conditions, such as lymphoid disorders, Alzheimer's disease, diabetes mellitus type 2, chronic inflammatory processes, and cancers. Amyloid fibrils are commonly diagnosed by
arxiv
Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis [PDF]
, 1995 Andréa C. LeBlanc
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Opinion: The Potential Role of Amyloid Beta Peptides as Biomarkers of Subconcussion and Concussion. [PDF]
Front Neurol, 2022 Boutté AM, Thangavelu B, Anagli J.
europepmc +1 more source
Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers [PDF]
, 2019 Desmin-associated myofibrillar myopathy (MFM) has pathologic similarities to neurodegeneration-associated protein aggregate diseases. Desmin is an abundant muscle-specific intermediate filament, and disease mutations lead to its aggregation in cells ...
Arhzaouy, Khalid +6 more
core +1 more source
Quantitative Analysis of Fluorescent Sensor Arrays
Analysis &Sensing, Accepted Article.Fluorescent sensor arrays address the limitations of a single sensor by leveraging multiple sensing elements to generate unique response patterns for each of the analyte of interest. This approach has emerged as a powerful tool for identifying and analysing intricate chemical and biological environments using various multivariate analytical tools such ...
Karandeep Grover +3 more
wiley +1 more source
Amyloid beta peptides (Aβ) from Alzheimer's disease neuronal secretome induce endothelial activation in a human cerebral microvessel model. [PDF]
Neurobiol Dis, 2023 Shin YJ +8 more
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The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth [PDF]
arXiv, 2019 Many proteins have the potential to aggregate into amyloid fibrils, which are associated with a wide range of human disorders including Alzheimer's and Parkinson's disease. In contrast to that of folded proteins, the thermodynamic stability of amyloid fibrils is not well understood: specifically the balance between entropic and enthalpic terms ...
arxiv